Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | OXSTRESS_RPETWO_DN |
| Enrichment Score (ES) | -0.52546346 |
| Normalized Enrichment Score (NES) | -1.7970529 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.038228374 |
| FWER p-Value | 0.973 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 49 | 0.501 | 0.0420 | No |
| 2 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 214 | 0.304 | 0.0574 | No |
| 3 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 1404 | 0.119 | -0.0215 | No |
| 4 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1526 | 0.112 | -0.0204 | No |
| 5 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1609 | 0.108 | -0.0167 | No |
| 6 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 2071 | 0.092 | -0.0431 | No |
| 7 | HGFAC | HGFAC Entrez, Source | HGF activator | 2074 | 0.092 | -0.0349 | No |
| 8 | HGF | HGF Entrez, Source | hepatocyte growth factor (hepapoietin A; scatter factor) | 2125 | 0.090 | -0.0304 | No |
| 9 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2527 | 0.079 | -0.0534 | No |
| 10 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 2759 | 0.072 | -0.0643 | No |
| 11 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2765 | 0.072 | -0.0580 | No |
| 12 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 2927 | 0.068 | -0.0640 | No |
| 13 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 2929 | 0.068 | -0.0578 | No |
| 14 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2940 | 0.068 | -0.0524 | No |
| 15 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 3063 | 0.065 | -0.0556 | No |
| 16 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3241 | 0.061 | -0.0634 | No |
| 17 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 3628 | 0.053 | -0.0876 | No |
| 18 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 3797 | 0.050 | -0.0957 | No |
| 19 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 3828 | 0.049 | -0.0935 | No |
| 20 | FASTK | FASTK Entrez, Source | Fas-activated serine/threonine kinase | 4138 | 0.044 | -0.1128 | No |
| 21 | PHB | PHB Entrez, Source | prohibitin | 4309 | 0.041 | -0.1219 | No |
| 22 | STCH | STCH Entrez, Source | stress 70 protein chaperone, microsome-associated, 60kDa | 4413 | 0.039 | -0.1260 | No |
| 23 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 4470 | 0.038 | -0.1268 | No |
| 24 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 4490 | 0.038 | -0.1247 | No |
| 25 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 4722 | 0.034 | -0.1391 | No |
| 26 | IL3 | IL3 Entrez, Source | interleukin 3 (colony-stimulating factor, multiple) | 5080 | 0.028 | -0.1635 | No |
| 27 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 5137 | 0.027 | -0.1652 | No |
| 28 | BRAF | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 5266 | 0.025 | -0.1725 | No |
| 29 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6041 | 0.014 | -0.2297 | No |
| 30 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 6114 | 0.013 | -0.2340 | No |
| 31 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6158 | 0.012 | -0.2361 | No |
| 32 | HINT1 | HINT1 Entrez, Source | histidine triad nucleotide binding protein 1 | 6763 | 0.003 | -0.2814 | No |
| 33 | TSG101 | TSG101 Entrez, Source | tumor susceptibility gene 101 | 6868 | 0.002 | -0.2891 | No |
| 34 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 7446 | -0.007 | -0.3320 | No |
| 35 | UBE2A | UBE2A Entrez, Source | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 7458 | -0.007 | -0.3322 | No |
| 36 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 7495 | -0.007 | -0.3342 | No |
| 37 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 7659 | -0.010 | -0.3456 | No |
| 38 | ERBB4 | ERBB4 Entrez, Source | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 8064 | -0.016 | -0.3747 | No |
| 39 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 8308 | -0.020 | -0.3912 | No |
| 40 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 8312 | -0.020 | -0.3896 | No |
| 41 | CDK9 | CDK9 Entrez, Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 8367 | -0.021 | -0.3917 | No |
| 42 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 8656 | -0.026 | -0.4111 | No |
| 43 | SPINT2 | SPINT2 Entrez, Source | serine peptidase inhibitor, Kunitz type, 2 | 8659 | -0.026 | -0.4089 | No |
| 44 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 8916 | -0.030 | -0.4255 | No |
| 45 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 9083 | -0.034 | -0.4349 | No |
| 46 | CSNK1G2 | CSNK1G2 Entrez, Source | casein kinase 1, gamma 2 | 9127 | -0.035 | -0.4350 | No |
| 47 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 9612 | -0.044 | -0.4675 | No |
| 48 | S100A1 | S100A1 Entrez, Source | S100 calcium binding protein A1 | 9735 | -0.046 | -0.4725 | No |
| 49 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 10008 | -0.052 | -0.4882 | No |
| 50 | GAK | GAK Entrez, Source | cyclin G associated kinase | 10046 | -0.053 | -0.4862 | No |
| 51 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 10210 | -0.057 | -0.4933 | No |
| 52 | RNH1 | RNH1 Entrez, Source | ribonuclease/angiogenin inhibitor 1 | 10580 | -0.066 | -0.5151 | No |
| 53 | TSC2 | TSC2 Entrez, Source | tuberous sclerosis 2 | 10719 | -0.070 | -0.5190 | Yes |
| 54 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 10726 | -0.071 | -0.5131 | Yes |
| 55 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 10761 | -0.072 | -0.5091 | Yes |
| 56 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 10796 | -0.072 | -0.5050 | Yes |
| 57 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 10828 | -0.073 | -0.5007 | Yes |
| 58 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 10949 | -0.077 | -0.5027 | Yes |
| 59 | GTF2B | GTF2B Entrez, Source | general transcription factor IIB | 10959 | -0.077 | -0.4964 | Yes |
| 60 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 10999 | -0.079 | -0.4921 | Yes |
| 61 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 11246 | -0.088 | -0.5027 | Yes |
| 62 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 11499 | -0.099 | -0.5126 | Yes |
| 63 | ACTB | ACTB Entrez, Source | actin, beta | 11552 | -0.102 | -0.5073 | Yes |
| 64 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 11553 | -0.102 | -0.4980 | Yes |
| 65 | ITGAL | ITGAL Entrez, Source | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 11774 | -0.112 | -0.5043 | Yes |
| 66 | CAPN2 | CAPN2 Entrez, Source | calpain 2, (m/II) large subunit | 11927 | -0.120 | -0.5048 | Yes |
| 67 | CLU | CLU Entrez, Source | clusterin | 12046 | -0.128 | -0.5020 | Yes |
| 68 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 12070 | -0.129 | -0.4920 | Yes |
| 69 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 12170 | -0.136 | -0.4870 | Yes |
| 70 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 12256 | -0.144 | -0.4803 | Yes |
| 71 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 12262 | -0.145 | -0.4674 | Yes |
| 72 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 12348 | -0.153 | -0.4599 | Yes |
| 73 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 12355 | -0.153 | -0.4463 | Yes |
| 74 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 12553 | -0.179 | -0.4449 | Yes |
| 75 | CD47 | CD47 Entrez, Source | CD47 molecule | 12700 | -0.205 | -0.4372 | Yes |
| 76 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 12819 | -0.229 | -0.4251 | Yes |
| 77 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | -0.4060 | Yes |
| 78 | ZYX | ZYX Entrez, Source | zyxin | 12928 | -0.262 | -0.3875 | Yes |
| 79 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 12930 | -0.262 | -0.3637 | Yes |
| 80 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13200 | -0.467 | -0.3413 | Yes |
| 81 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13271 | -0.644 | -0.2878 | Yes |
| 82 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13282 | -0.665 | -0.2279 | Yes |
| 83 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13330 | -1.167 | -0.1249 | Yes |
| 84 | CPE | CPE Entrez, Source | carboxypeptidase E | 13337 | -1.377 | 0.0004 | Yes |
