Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | OXSTRESS_RPE_HNETBH_DN |
| Enrichment Score (ES) | -0.5835782 |
| Normalized Enrichment Score (NES) | -1.7023973 |
| Nominal p-value | 0.0051282053 |
| FDR q-value | 0.062430996 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 214 | 0.304 | 0.0498 | No |
| 2 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 2071 | 0.092 | -0.0698 | No |
| 3 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 2927 | 0.068 | -0.1193 | No |
| 4 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 3063 | 0.065 | -0.1153 | No |
| 5 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3241 | 0.061 | -0.1153 | No |
| 6 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 3628 | 0.053 | -0.1328 | No |
| 7 | FASTK | FASTK Entrez, Source | Fas-activated serine/threonine kinase | 4138 | 0.044 | -0.1615 | No |
| 8 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 4722 | 0.034 | -0.1980 | No |
| 9 | IL3 | IL3 Entrez, Source | interleukin 3 (colony-stimulating factor, multiple) | 5080 | 0.028 | -0.2188 | No |
| 10 | BRAF | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 5266 | 0.025 | -0.2272 | No |
| 11 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 6114 | 0.013 | -0.2881 | No |
| 12 | TSG101 | TSG101 Entrez, Source | tumor susceptibility gene 101 | 6868 | 0.002 | -0.3443 | No |
| 13 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 7495 | -0.007 | -0.3898 | No |
| 14 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 7659 | -0.010 | -0.3999 | No |
| 15 | ERBB4 | ERBB4 Entrez, Source | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 8064 | -0.016 | -0.4268 | No |
| 16 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 8916 | -0.030 | -0.4842 | No |
| 17 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 9083 | -0.034 | -0.4893 | No |
| 18 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 9612 | -0.044 | -0.5195 | No |
| 19 | S100A1 | S100A1 Entrez, Source | S100 calcium binding protein A1 | 9735 | -0.046 | -0.5186 | No |
| 20 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 10008 | -0.052 | -0.5278 | No |
| 21 | GAK | GAK Entrez, Source | cyclin G associated kinase | 10046 | -0.053 | -0.5191 | No |
| 22 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 10210 | -0.057 | -0.5190 | No |
| 23 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 10761 | -0.072 | -0.5448 | No |
| 24 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 10796 | -0.072 | -0.5317 | No |
| 25 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 10828 | -0.073 | -0.5182 | No |
| 26 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 10999 | -0.079 | -0.5139 | No |
| 27 | CAPN2 | CAPN2 Entrez, Source | calpain 2, (m/II) large subunit | 11927 | -0.120 | -0.5576 | Yes |
| 28 | CLU | CLU Entrez, Source | clusterin | 12046 | -0.128 | -0.5387 | Yes |
| 29 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 12355 | -0.153 | -0.5286 | Yes |
| 30 | CD47 | CD47 Entrez, Source | CD47 molecule | 12700 | -0.205 | -0.5101 | Yes |
| 31 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 12819 | -0.229 | -0.4693 | Yes |
| 32 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | -0.4202 | Yes |
| 33 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 12930 | -0.262 | -0.3690 | Yes |
| 34 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13200 | -0.467 | -0.2879 | Yes |
| 35 | CPE | CPE Entrez, Source | carboxypeptidase E | 13337 | -1.377 | 0.0004 | Yes |
