Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | PAR1PATHWAY |
| Enrichment Score (ES) | -0.75086087 |
| Normalized Enrichment Score (NES) | -1.7581615 |
| Nominal p-value | 0.0037105752 |
| FDR q-value | 0.044731867 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 2335 | 0.084 | -0.1413 | No |
| 2 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 2401 | 0.082 | -0.1129 | No |
| 3 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 3999 | 0.046 | -0.2140 | No |
| 4 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 4760 | 0.033 | -0.2576 | No |
| 5 | F2RL3 | F2RL3 Entrez, Source | coagulation factor II (thrombin) receptor-like 3 | 5162 | 0.027 | -0.2769 | No |
| 6 | GNA12 | GNA12 Entrez, Source | guanine nucleotide binding protein (G protein) alpha 12 | 5751 | 0.018 | -0.3137 | No |
| 7 | ARHGEF1 | ARHGEF1 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 1 | 6303 | 0.010 | -0.3512 | No |
| 8 | ROCK1 | ROCK1 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 1 | 11231 | -0.087 | -0.6858 | No |
| 9 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 12099 | -0.132 | -0.6978 | Yes |
| 10 | PLCB1 | PLCB1 Entrez, Source | phospholipase C, beta 1 (phosphoinositide-specific) | 12183 | -0.138 | -0.6486 | Yes |
| 11 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 12403 | -0.158 | -0.6012 | Yes |
| 12 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 12536 | -0.176 | -0.5400 | Yes |
| 13 | PTK2B | PTK2B Entrez, Source | PTK2B protein tyrosine kinase 2 beta | 12874 | -0.243 | -0.4671 | Yes |
| 14 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13262 | -0.580 | -0.2623 | Yes |
| 15 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13282 | -0.665 | 0.0045 | Yes |
