Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY |
| Enrichment Score (ES) | -0.48778924 |
| Normalized Enrichment Score (NES) | -1.7061929 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.061618887 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PRLR | PRLR Entrez, Source | prolactin receptor | 257 | 0.285 | 0.0046 | No |
| 2 | ADRB2 | ADRB2 Entrez, Source | adrenergic, beta-2-, receptor, surface | 617 | 0.184 | -0.0070 | No |
| 3 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 829 | 0.160 | -0.0095 | No |
| 4 | BCL2L10 | BCL2L10 Entrez, Source | BCL2-like 10 (apoptosis facilitator) | 975 | 0.147 | -0.0081 | No |
| 5 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 986 | 0.146 | 0.0035 | No |
| 6 | CENTD2 | CENTD2 Entrez, Source | centaurin, delta 2 | 1137 | 0.135 | 0.0035 | No |
| 7 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 1518 | 0.112 | -0.0157 | No |
| 8 | CCKBR | CCKBR Entrez, Source | cholecystokinin B receptor | 1665 | 0.106 | -0.0178 | No |
| 9 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 1748 | 0.103 | -0.0153 | No |
| 10 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1856 | 0.099 | -0.0151 | No |
| 11 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 1997 | 0.094 | -0.0177 | No |
| 12 | C5AR1 | C5AR1 Entrez, Source | complement component 5a receptor 1 | 2296 | 0.085 | -0.0331 | No |
| 13 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 2335 | 0.084 | -0.0288 | No |
| 14 | PICK1 | PICK1 Entrez, Source | protein interacting with PRKCA 1 | 2572 | 0.077 | -0.0402 | No |
| 15 | PLCB2 | PLCB2 Entrez, Source | phospholipase C, beta 2 | 2782 | 0.072 | -0.0499 | No |
| 16 | GNAS | GNAS Entrez, Source | GNAS complex locus | 2815 | 0.071 | -0.0463 | No |
| 17 | UBE2N | UBE2N Entrez, Source | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 2977 | 0.067 | -0.0529 | No |
| 18 | CD4 | CD4 Entrez, Source | CD4 molecule | 2984 | 0.067 | -0.0477 | No |
| 19 | CALCA | CALCA Entrez, Source | calcitonin/calcitonin-related polypeptide, alpha | 3026 | 0.066 | -0.0452 | No |
| 20 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 3416 | 0.058 | -0.0697 | No |
| 21 | AVPR2 | AVPR2 Entrez, Source | arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) | 3571 | 0.054 | -0.0768 | No |
| 22 | AVPR1B | AVPR1B Entrez, Source | arginine vasopressin receptor 1B | 3691 | 0.052 | -0.0814 | No |
| 23 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 4018 | 0.046 | -0.1022 | No |
| 24 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 4030 | 0.046 | -0.0991 | No |
| 25 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | -0.0990 | No |
| 26 | EDG2 | EDG2 Entrez, Source | endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 | 4234 | 0.042 | -0.1071 | No |
| 27 | ACR | ACR Entrez, Source | acrosin | 4402 | 0.039 | -0.1164 | No |
| 28 | CRHR1 | CRHR1 Entrez, Source | corticotropin releasing hormone receptor 1 | 4458 | 0.038 | -0.1173 | No |
| 29 | GHRHR | GHRHR Entrez, Source | growth hormone releasing hormone receptor | 4537 | 0.037 | -0.1200 | No |
| 30 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4891 | 0.031 | -0.1441 | No |
| 31 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 4920 | 0.030 | -0.1437 | No |
| 32 | ADRB3 | ADRB3 Entrez, Source | adrenergic, beta-3-, receptor | 5121 | 0.027 | -0.1565 | No |
| 33 | ADRB1 | ADRB1 Entrez, Source | adrenergic, beta-1-, receptor | 5390 | 0.023 | -0.1748 | No |
| 34 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 5815 | 0.017 | -0.2054 | No |
| 35 | ADCYAP1 | ADCYAP1 Entrez, Source | adenylate cyclase activating polypeptide 1 (pituitary) | 5921 | 0.015 | -0.2120 | No |
| 36 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 5959 | 0.015 | -0.2136 | No |
| 37 | IFNB1 | IFNB1 Entrez, Source | interferon, beta 1, fibroblast | 6100 | 0.013 | -0.2231 | No |
| 38 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6158 | 0.012 | -0.2264 | No |
| 39 | ARHGAP27 | ARHGAP27 Entrez, Source | Rho GTPase activating protein 27 | 6496 | 0.006 | -0.2513 | No |
| 40 | MAP3K10 | MAP3K10 Entrez, Source | mitogen-activated protein kinase kinase kinase 10 | 6666 | 0.004 | -0.2637 | No |
| 41 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 6707 | 0.004 | -0.2664 | No |
| 42 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 6755 | 0.003 | -0.2697 | No |
| 43 | LYK5 | LYK5 Entrez, Source | - | 6784 | 0.003 | -0.2716 | No |
| 44 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 6861 | 0.002 | -0.2771 | No |
| 45 | CARTPT | CARTPT Entrez, Source | CART prepropeptide | 7367 | -0.006 | -0.3149 | No |
| 46 | NCSTN | NCSTN Entrez, Source | nicastrin | 7456 | -0.007 | -0.3209 | No |
| 47 | GAP43 | GAP43 Entrez, Source | growth associated protein 43 | 7485 | -0.007 | -0.3224 | No |
| 48 | PSENEN | PSENEN Entrez, Source | presenilin enhancer 2 homolog (C. elegans) | 7540 | -0.008 | -0.3258 | No |
| 49 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 7574 | -0.009 | -0.3276 | No |
| 50 | CHRNA7 | CHRNA7 Entrez, Source | cholinergic receptor, nicotinic, alpha 7 | 7665 | -0.010 | -0.3336 | No |
| 51 | SERINC1 | SERINC1 Entrez, Source | serine incorporator 1 | 7788 | -0.012 | -0.3418 | No |
| 52 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7883 | -0.013 | -0.3478 | No |
| 53 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 7982 | -0.015 | -0.3539 | No |
| 54 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 8085 | -0.016 | -0.3603 | No |
| 55 | NMUR2 | NMUR2 Entrez, Source | neuromedin U receptor 2 | 8190 | -0.018 | -0.3667 | No |
| 56 | GLP1R | GLP1R Entrez, Source | glucagon-like peptide 1 receptor | 8209 | -0.018 | -0.3665 | No |
| 57 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 8226 | -0.018 | -0.3661 | No |
| 58 | PIK3CB | PIK3CB Entrez, Source | phosphoinositide-3-kinase, catalytic, beta polypeptide | 8414 | -0.022 | -0.3785 | No |
| 59 | DRD5 | DRD5 Entrez, Source | dopamine receptor D5 | 8445 | -0.022 | -0.3789 | No |
| 60 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8480 | -0.023 | -0.3795 | No |
| 61 | DIABLO | DIABLO Entrez, Source | diablo homolog (Drosophila) | 8809 | -0.028 | -0.4019 | No |
| 62 | NMUR1 | NMUR1 Entrez, Source | neuromedin U receptor 1 | 8876 | -0.029 | -0.4044 | No |
| 63 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 9043 | -0.033 | -0.4142 | No |
| 64 | GNG3 | GNG3 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 3 | 9082 | -0.034 | -0.4142 | No |
| 65 | VCP | VCP Entrez, Source | valosin-containing protein | 9139 | -0.035 | -0.4155 | No |
| 66 | GRM4 | GRM4 Entrez, Source | glutamate receptor, metabotropic 4 | 9141 | -0.035 | -0.4127 | No |
| 67 | HIP1 | HIP1 Entrez, Source | huntingtin interacting protein 1 | 9248 | -0.037 | -0.4176 | No |
| 68 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 9287 | -0.038 | -0.4173 | No |
| 69 | EREG | EREG Entrez, Source | epiregulin | 9343 | -0.039 | -0.4182 | No |
| 70 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 9459 | -0.041 | -0.4235 | No |
| 71 | MADD | MADD Entrez, Source | MAP-kinase activating death domain | 9699 | -0.046 | -0.4377 | No |
| 72 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 9737 | -0.046 | -0.4366 | No |
| 73 | BAX | BAX Entrez, Source | BCL2-associated X protein | 9773 | -0.047 | -0.4352 | No |
| 74 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 9785 | -0.048 | -0.4321 | No |
| 75 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 9869 | -0.049 | -0.4342 | No |
| 76 | GIPR | GIPR Entrez, Source | gastric inhibitory polypeptide receptor | 9933 | -0.051 | -0.4347 | No |
| 77 | ADORA3 | ADORA3 Entrez, Source | adenosine A3 receptor | 10043 | -0.053 | -0.4385 | No |
| 78 | DBNL | DBNL Entrez, Source | drebrin-like | 10207 | -0.057 | -0.4460 | No |
| 79 | TAOK2 | TAOK2 Entrez, Source | TAO kinase 2 | 10217 | -0.057 | -0.4419 | No |
| 80 | ADRA2C | ADRA2C Entrez, Source | adrenergic, alpha-2C-, receptor | 10223 | -0.057 | -0.4374 | No |
| 81 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 10518 | -0.065 | -0.4542 | No |
| 82 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 10642 | -0.068 | -0.4577 | No |
| 83 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 10691 | -0.070 | -0.4555 | No |
| 84 | RALBP1 | RALBP1 Entrez, Source | ralA binding protein 1 | 10747 | -0.071 | -0.4537 | No |
| 85 | ADRA2A | ADRA2A Entrez, Source | adrenergic, alpha-2A-, receptor | 10829 | -0.073 | -0.4536 | No |
| 86 | GNA15 | GNA15 Entrez, Source | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 10833 | -0.073 | -0.4477 | No |
| 87 | CD81 | CD81 Entrez, Source | CD81 molecule | 11022 | -0.079 | -0.4552 | No |
| 88 | CALCR | CALCR Entrez, Source | calcitonin receptor | 11062 | -0.081 | -0.4514 | No |
| 89 | XRCC4 | XRCC4 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 4 | 11084 | -0.081 | -0.4461 | No |
| 90 | THY1 | THY1 Entrez, Source | Thy-1 cell surface antigen | 11169 | -0.084 | -0.4453 | No |
| 91 | PKN1 | PKN1 Entrez, Source | protein kinase N1 | 11530 | -0.101 | -0.4641 | No |
| 92 | EDNRA | EDNRA Entrez, Source | endothelin receptor type A | 11845 | -0.116 | -0.4780 | Yes |
| 93 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 11882 | -0.118 | -0.4708 | Yes |
| 94 | MTCH1 | MTCH1 Entrez, Source | mitochondrial carrier homolog 1 (C. elegans) | 12038 | -0.127 | -0.4718 | Yes |
| 95 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 12233 | -0.142 | -0.4744 | Yes |
| 96 | EDG5 | EDG5 Entrez, Source | endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 | 12247 | -0.143 | -0.4633 | Yes |
| 97 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 12403 | -0.158 | -0.4617 | Yes |
| 98 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 12427 | -0.161 | -0.4499 | Yes |
| 99 | PROK2 | PROK2 Entrez, Source | prokineticin 2 | 12439 | -0.162 | -0.4370 | Yes |
| 100 | APH1A | APH1A Entrez, Source | anterior pharynx defective 1 homolog A (C. elegans) | 12733 | -0.210 | -0.4415 | Yes |
| 101 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12826 | -0.231 | -0.4289 | Yes |
| 102 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13080 | -0.340 | -0.4194 | Yes |
| 103 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13085 | -0.343 | -0.3909 | Yes |
| 104 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 13103 | -0.358 | -0.3619 | Yes |
| 105 | PLCE1 | PLCE1 Entrez, Source | phospholipase C, epsilon 1 | 13110 | -0.363 | -0.3318 | Yes |
| 106 | AVPR1A | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 13117 | -0.366 | -0.3014 | Yes |
| 107 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 13156 | -0.411 | -0.2696 | Yes |
| 108 | SERINC5 | SERINC5 Entrez, Source | serine incorporator 5 | 13225 | -0.503 | -0.2324 | Yes |
| 109 | SERINC2 | SERINC2 Entrez, Source | serine incorporator 2 | 13234 | -0.520 | -0.1892 | Yes |
| 110 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13282 | -0.665 | -0.1367 | Yes |
| 111 | CD24 | CD24 Entrez, Source | CD24 molecule | 13341 | -1.675 | 0.0001 | Yes |
