Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS |
| Enrichment Score (ES) | -0.60653913 |
| Normalized Enrichment Score (NES) | -1.7967316 |
| Nominal p-value | 0.007017544 |
| FDR q-value | 0.037982248 |
| FWER p-Value | 0.973 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CFHR1 | CFHR1 Entrez, Source | complement factor H-related 1 | 271 | 0.278 | 0.0345 | No |
| 2 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 1090 | 0.138 | 0.0003 | No |
| 3 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1526 | 0.112 | -0.0103 | No |
| 4 | CD40LG | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 2885 | 0.069 | -0.0987 | No |
| 5 | UBE2N | UBE2N Entrez, Source | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 2977 | 0.067 | -0.0923 | No |
| 6 | CALCA | CALCA Entrez, Source | calcitonin/calcitonin-related polypeptide, alpha | 3026 | 0.066 | -0.0828 | No |
| 7 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 3374 | 0.059 | -0.0973 | No |
| 8 | IFNG | IFNG Entrez, Source | interferon, gamma | 4058 | 0.045 | -0.1397 | No |
| 9 | IL12A | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 5271 | 0.025 | -0.2258 | No |
| 10 | PTPRC | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 5608 | 0.020 | -0.2471 | No |
| 11 | IL12B | IL12B Entrez, Source | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 6003 | 0.014 | -0.2739 | No |
| 12 | IL4 | IL4 Entrez, Source | interleukin 4 | 6466 | 0.007 | -0.3073 | No |
| 13 | SART1 | SART1 Entrez, Source | squamous cell carcinoma antigen recognised by T cells | 6969 | 0.000 | -0.3449 | No |
| 14 | CD28 | CD28 Entrez, Source | CD28 molecule | 7763 | -0.011 | -0.4023 | No |
| 15 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7883 | -0.013 | -0.4086 | No |
| 16 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 8368 | -0.021 | -0.4408 | No |
| 17 | EREG | EREG Entrez, Source | epiregulin | 9343 | -0.039 | -0.5064 | No |
| 18 | MC4R | MC4R Entrez, Source | melanocortin 4 receptor | 10643 | -0.068 | -0.5905 | No |
| 19 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 10788 | -0.072 | -0.5871 | No |
| 20 | C2 | C2 Entrez, Source | complement component 2 | 11048 | -0.080 | -0.5907 | Yes |
| 21 | IL7 | IL7 Entrez, Source | interleukin 7 | 11123 | -0.083 | -0.5799 | Yes |
| 22 | THY1 | THY1 Entrez, Source | Thy-1 cell surface antigen | 11169 | -0.084 | -0.5666 | Yes |
| 23 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 11246 | -0.088 | -0.5550 | Yes |
| 24 | KL | KL Entrez, Source | klotho | 11354 | -0.093 | -0.5447 | Yes |
| 25 | ATP6AP2 | ATP6AP2 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 2 | 11554 | -0.102 | -0.5395 | Yes |
| 26 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12011 | -0.126 | -0.5489 | Yes |
| 27 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12112 | -0.132 | -0.5303 | Yes |
| 28 | PROK2 | PROK2 Entrez, Source | prokineticin 2 | 12439 | -0.162 | -0.5228 | Yes |
| 29 | SPHK1 | SPHK1 Entrez, Source | sphingosine kinase 1 | 12507 | -0.172 | -0.4939 | Yes |
| 30 | CD47 | CD47 Entrez, Source | CD47 molecule | 12700 | -0.205 | -0.4678 | Yes |
| 31 | TNFSF13 | TNFSF13 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 13 | 13014 | -0.298 | -0.4324 | Yes |
| 32 | FST | FST Entrez, Source | follistatin | 13045 | -0.318 | -0.3719 | Yes |
| 33 | CD276 | CD276 Entrez, Source | CD276 molecule | 13052 | -0.320 | -0.3092 | Yes |
| 34 | CD24 | CD24 Entrez, Source | CD24 molecule | 13341 | -1.675 | 0.0001 | Yes |
