Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | PPARAPATHWAY |
| Enrichment Score (ES) | 0.45926404 |
| Normalized Enrichment Score (NES) | 1.4812356 |
| Nominal p-value | 0.025229357 |
| FDR q-value | 0.1329996 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 2 | 1.112 | 0.1494 | Yes |
| 2 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 6 | 0.908 | 0.2713 | Yes |
| 3 | APOA2 | APOA2 Entrez, Source | apolipoprotein A-II | 22 | 0.601 | 0.3510 | Yes |
| 4 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 104 | 0.416 | 0.4008 | Yes |
| 5 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 266 | 0.281 | 0.4265 | Yes |
| 6 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 566 | 0.190 | 0.4295 | Yes |
| 7 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 583 | 0.188 | 0.4536 | Yes |
| 8 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 800 | 0.163 | 0.4593 | Yes |
| 9 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 1252 | 0.127 | 0.4424 | No |
| 10 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1609 | 0.108 | 0.4302 | No |
| 11 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 1781 | 0.102 | 0.4310 | No |
| 12 | SRA1 | SRA1 Entrez, Source | steroid receptor RNA activator 1 | 2136 | 0.090 | 0.4165 | No |
| 13 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 2241 | 0.087 | 0.4204 | No |
| 14 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 2401 | 0.082 | 0.4195 | No |
| 15 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 2496 | 0.080 | 0.4232 | No |
| 16 | PRKAR2A | PRKAR2A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 2568 | 0.078 | 0.4283 | No |
| 17 | HSD17B4 | HSD17B4 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 4 | 2625 | 0.076 | 0.4342 | No |
| 18 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2765 | 0.072 | 0.4335 | No |
| 19 | MRPL11 | MRPL11 Entrez, Source | mitochondrial ribosomal protein L11 | 3529 | 0.055 | 0.3836 | No |
| 20 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 3999 | 0.046 | 0.3545 | No |
| 21 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 4169 | 0.043 | 0.3477 | No |
| 22 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 4760 | 0.033 | 0.3078 | No |
| 23 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 4806 | 0.032 | 0.3087 | No |
| 24 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 6673 | 0.004 | 0.1690 | No |
| 25 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6739 | 0.003 | 0.1646 | No |
| 26 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 8113 | -0.016 | 0.0636 | No |
| 27 | SP1 | SP1 Entrez, Source | Sp1 transcription factor | 8115 | -0.016 | 0.0657 | No |
| 28 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 8175 | -0.018 | 0.0636 | No |
| 29 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 8561 | -0.024 | 0.0379 | No |
| 30 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 9755 | -0.047 | -0.0455 | No |
| 31 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 10137 | -0.055 | -0.0667 | No |
| 32 | NCOR1 | NCOR1 Entrez, Source | nuclear receptor co-repressor 1 | 10165 | -0.056 | -0.0612 | No |
| 33 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 10251 | -0.058 | -0.0598 | No |
| 34 | LPL | LPL Entrez, Source | lipoprotein lipase | 10988 | -0.078 | -0.1046 | No |
| 35 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 10990 | -0.078 | -0.0942 | No |
| 36 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 11002 | -0.079 | -0.0844 | No |
| 37 | JUN | JUN Entrez, Source | jun oncogene | 11756 | -0.111 | -0.1261 | No |
| 38 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12441 | -0.162 | -0.1556 | No |
| 39 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 12536 | -0.176 | -0.1390 | No |
| 40 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 12903 | -0.254 | -0.1324 | No |
| 41 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13042 | -0.314 | -0.1005 | No |
| 42 | PDGFA | PDGFA Entrez, Source | platelet-derived growth factor alpha polypeptide | 13176 | -0.433 | -0.0523 | No |
| 43 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13211 | -0.481 | 0.0098 | No |
