Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | PROSTAGLANDIN_SYNTHESIS_REGULATION |
| Enrichment Score (ES) | -0.6418917 |
| Normalized Enrichment Score (NES) | -1.7679474 |
| Nominal p-value | 0.0018248175 |
| FDR q-value | 0.041991867 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 370 | 0.242 | 0.0258 | No |
| 2 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 1288 | 0.125 | -0.0154 | No |
| 3 | EDNRB | EDNRB Entrez, Source | endothelin receptor type B | 1747 | 0.103 | -0.0269 | No |
| 4 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 1781 | 0.102 | -0.0068 | No |
| 5 | TBXAS1 | TBXAS1 Entrez, Source | thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) | 2199 | 0.088 | -0.0186 | No |
| 6 | PTGER2 | PTGER2 Entrez, Source | prostaglandin E receptor 2 (subtype EP2), 53kDa | 2838 | 0.070 | -0.0509 | No |
| 7 | SCGB1A1 | SCGB1A1 Entrez, Source | secretoglobin, family 1A, member 1 (uteroglobin) | 3503 | 0.056 | -0.0884 | No |
| 8 | PTGER1 | PTGER1 Entrez, Source | prostaglandin E receptor 1 (subtype EP1), 42kDa | 3754 | 0.051 | -0.0959 | No |
| 9 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 4542 | 0.037 | -0.1468 | No |
| 10 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 4803 | 0.032 | -0.1591 | No |
| 11 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 4887 | 0.031 | -0.1585 | No |
| 12 | ANXA8 | ANXA8 Entrez, Source | annexin A8 | 5494 | 0.022 | -0.1991 | No |
| 13 | PTGFR | PTGFR Entrez, Source | prostaglandin F receptor (FP) | 5917 | 0.015 | -0.2274 | No |
| 14 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 6738 | 0.003 | -0.2882 | No |
| 15 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9062 | -0.033 | -0.4553 | No |
| 16 | PRL | PRL Entrez, Source | prolactin | 9700 | -0.046 | -0.4930 | No |
| 17 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 10102 | -0.054 | -0.5111 | No |
| 18 | EDNRA | EDNRA Entrez, Source | endothelin receptor type A | 11845 | -0.116 | -0.6161 | Yes |
| 19 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12040 | -0.127 | -0.6025 | Yes |
| 20 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 12179 | -0.137 | -0.5824 | Yes |
| 21 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 12414 | -0.160 | -0.5646 | Yes |
| 22 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12661 | -0.197 | -0.5395 | Yes |
| 23 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12706 | -0.206 | -0.4972 | Yes |
| 24 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13069 | -0.331 | -0.4510 | Yes |
| 25 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13165 | -0.424 | -0.3643 | Yes |
| 26 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 13172 | -0.431 | -0.2692 | Yes |
| 27 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | 0.0005 | Yes |
