Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | PYRIMIDINE_METABOLISM |
| Enrichment Score (ES) | 0.5525837 |
| Normalized Enrichment Score (NES) | 1.6251236 |
| Nominal p-value | 0.022573363 |
| FDR q-value | 0.060044613 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DPYS | DPYS Entrez, Source | dihydropyrimidinase | 90 | 0.425 | 0.1568 | Yes |
| 2 | UPB1 | UPB1 Entrez, Source | ureidopropionase, beta | 177 | 0.330 | 0.2774 | Yes |
| 3 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 303 | 0.265 | 0.3700 | Yes |
| 4 | AK3L1 | AK3L1 Entrez, Source | adenylate kinase 3-like 1 | 442 | 0.218 | 0.4435 | Yes |
| 5 | POLR1B | POLR1B Entrez, Source | polymerase (RNA) I polypeptide B, 128kDa | 672 | 0.177 | 0.4943 | Yes |
| 6 | NT5E | NT5E Entrez, Source | 5'-nucleotidase, ecto (CD73) | 752 | 0.167 | 0.5526 | Yes |
| 7 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 2764 | 0.072 | 0.4293 | No |
| 8 | ENTPD1 | ENTPD1 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 1 | 2818 | 0.071 | 0.4526 | No |
| 9 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 3035 | 0.066 | 0.4617 | No |
| 10 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3161 | 0.063 | 0.4766 | No |
| 11 | POLR2C | POLR2C Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 3222 | 0.062 | 0.4958 | No |
| 12 | POLG | POLG Entrez, Source | polymerase (DNA directed), gamma | 3231 | 0.062 | 0.5189 | No |
| 13 | UPP1 | UPP1 Entrez, Source | uridine phosphorylase 1 | 4127 | 0.044 | 0.4687 | No |
| 14 | AK3 | AK3 Entrez, Source | adenylate kinase 3 | 5540 | 0.021 | 0.3707 | No |
| 15 | CTPS2 | CTPS2 Entrez, Source | CTP synthase II | 5705 | 0.019 | 0.3656 | No |
| 16 | POLR2F | POLR2F Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide F | 5780 | 0.018 | 0.3668 | No |
| 17 | NUDT2 | NUDT2 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | 5879 | 0.016 | 0.3656 | No |
| 18 | DHODH | DHODH Entrez, Source | dihydroorotate dehydrogenase | 5933 | 0.015 | 0.3675 | No |
| 19 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 6095 | 0.013 | 0.3603 | No |
| 20 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 6256 | 0.010 | 0.3523 | No |
| 21 | NME2 | NME2 Entrez, Source | non-metastatic cells 2, protein (NM23B) expressed in | 6499 | 0.006 | 0.3366 | No |
| 22 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | 0.3016 | No |
| 23 | CMPK | CMPK Entrez, Source | cytidylate kinase | 7736 | -0.011 | 0.2481 | No |
| 24 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 9135 | -0.035 | 0.1564 | No |
| 25 | CANT1 | CANT1 Entrez, Source | calcium activated nucleotidase 1 | 9798 | -0.048 | 0.1251 | No |
| 26 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 9909 | -0.050 | 0.1362 | No |
| 27 | POLR2G | POLR2G Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide G | 10010 | -0.052 | 0.1488 | No |
| 28 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 10990 | -0.078 | 0.1053 | No |
| 29 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12607 | -0.185 | 0.0552 | No |
