Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | RESPONSE_TO_HYPOXIA |
| Enrichment Score (ES) | -0.67017967 |
| Normalized Enrichment Score (NES) | -1.7720333 |
| Nominal p-value | 0.007707129 |
| FDR q-value | 0.04118547 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 2628 | 0.076 | -0.1715 | No |
| 2 | NARFL | NARFL Entrez, Source | nuclear prelamin A recognition factor-like | 2903 | 0.069 | -0.1687 | No |
| 3 | CLDN3 | CLDN3 Entrez, Source | claudin 3 | 3644 | 0.053 | -0.2062 | No |
| 4 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 5283 | 0.025 | -0.3207 | No |
| 5 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 5606 | 0.020 | -0.3379 | No |
| 6 | ARNT2 | ARNT2 Entrez, Source | aryl-hydrocarbon receptor nuclear translocator 2 | 5871 | 0.016 | -0.3523 | No |
| 7 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 7492 | -0.007 | -0.4714 | No |
| 8 | CHRNA7 | CHRNA7 Entrez, Source | cholinergic receptor, nicotinic, alpha 7 | 7665 | -0.010 | -0.4809 | No |
| 9 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 7875 | -0.013 | -0.4921 | No |
| 10 | EGLN1 | EGLN1 Entrez, Source | egl nine homolog 1 (C. elegans) | 8000 | -0.015 | -0.4963 | No |
| 11 | CHRNA4 | CHRNA4 Entrez, Source | cholinergic receptor, nicotinic, alpha 4 | 8499 | -0.023 | -0.5258 | No |
| 12 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 8561 | -0.024 | -0.5222 | No |
| 13 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 9459 | -0.041 | -0.5756 | No |
| 14 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 9737 | -0.046 | -0.5806 | No |
| 15 | CHRNB2 | CHRNB2 Entrez, Source | cholinergic receptor, nicotinic, beta 2 (neuronal) | 9835 | -0.049 | -0.5713 | No |
| 16 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 11002 | -0.079 | -0.6321 | Yes |
| 17 | SMAD4 | SMAD4 Entrez, Source | SMAD, mothers against DPP homolog 4 (Drosophila) | 11091 | -0.082 | -0.6109 | Yes |
| 18 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 11882 | -0.118 | -0.6300 | Yes |
| 19 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12112 | -0.132 | -0.6022 | Yes |
| 20 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 12528 | -0.175 | -0.5737 | Yes |
| 21 | PLOD1 | PLOD1 Entrez, Source | procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 | 12626 | -0.189 | -0.5167 | Yes |
| 22 | CD24 | CD24 Entrez, Source | CD24 molecule | 13341 | -1.675 | 0.0001 | Yes |
