Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | SANA_TNFA_ENDOTHELIAL_DN |
| Enrichment Score (ES) | -0.56292033 |
| Normalized Enrichment Score (NES) | -1.791663 |
| Nominal p-value | 0.003533569 |
| FDR q-value | 0.039137293 |
| FWER p-Value | 0.982 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 391 | 0.235 | 0.0012 | No |
| 2 | NT5E | NT5E Entrez, Source | 5'-nucleotidase, ecto (CD73) | 752 | 0.167 | -0.0040 | No |
| 3 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 1532 | 0.112 | -0.0480 | No |
| 4 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 1708 | 0.105 | -0.0475 | No |
| 5 | PCTP | PCTP Entrez, Source | phosphatidylcholine transfer protein | 1826 | 0.100 | -0.0432 | No |
| 6 | EMCN | EMCN Entrez, Source | endomucin | 1920 | 0.097 | -0.0376 | No |
| 7 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2131 | 0.090 | -0.0416 | No |
| 8 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 2189 | 0.088 | -0.0343 | No |
| 9 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 2205 | 0.088 | -0.0239 | No |
| 10 | JAG2 | JAG2 Entrez, Source | jagged 2 | 2207 | 0.088 | -0.0125 | No |
| 11 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 2239 | 0.087 | -0.0035 | No |
| 12 | ACE | ACE Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 2622 | 0.076 | -0.0224 | No |
| 13 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 2628 | 0.076 | -0.0129 | No |
| 14 | MTUS1 | MTUS1 Entrez, Source | mitochondrial tumor suppressor 1 | 2646 | 0.075 | -0.0043 | No |
| 15 | ANTXR1 | ANTXR1 Entrez, Source | anthrax toxin receptor 1 | 3443 | 0.057 | -0.0568 | No |
| 16 | CALCRL | CALCRL Entrez, Source | calcitonin receptor-like | 3492 | 0.056 | -0.0531 | No |
| 17 | ATP5A1 | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 3850 | 0.049 | -0.0736 | No |
| 18 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 4357 | 0.040 | -0.1064 | No |
| 19 | PRKCH | PRKCH Entrez, Source | protein kinase C, eta | 4516 | 0.038 | -0.1134 | No |
| 20 | BGN | BGN Entrez, Source | biglycan | 5847 | 0.017 | -0.2113 | No |
| 21 | ARL5A | ARL5A Entrez, Source | ADP-ribosylation factor-like 5A | 6062 | 0.013 | -0.2257 | No |
| 22 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 6320 | 0.009 | -0.2438 | No |
| 23 | TPT1 | TPT1 Entrez, Source | tumor protein, translationally-controlled 1 | 6352 | 0.009 | -0.2450 | No |
| 24 | APLN | APLN Entrez, Source | apelin, AGTRL1 ligand | 6690 | 0.004 | -0.2698 | No |
| 25 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 7002 | -0.000 | -0.2932 | No |
| 26 | VWF | VWF Entrez, Source | von Willebrand factor | 7187 | -0.003 | -0.3067 | No |
| 27 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 7269 | -0.004 | -0.3122 | No |
| 28 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 7429 | -0.006 | -0.3234 | No |
| 29 | DNAH11 | DNAH11 Entrez, Source | dynein, axonemal, heavy chain 11 | 7759 | -0.011 | -0.3466 | No |
| 30 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 8154 | -0.017 | -0.3741 | No |
| 31 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 8384 | -0.021 | -0.3885 | No |
| 32 | PALMD | PALMD Entrez, Source | palmdelphin | 9671 | -0.045 | -0.4794 | No |
| 33 | HTR1B | HTR1B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1B | 10114 | -0.055 | -0.5056 | No |
| 34 | ATP1B3 | ATP1B3 Entrez, Source | ATPase, Na+/K+ transporting, beta 3 polypeptide | 10160 | -0.056 | -0.5017 | No |
| 35 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 10171 | -0.056 | -0.4951 | No |
| 36 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 10391 | -0.061 | -0.5036 | No |
| 37 | ARL6IP1 | ARL6IP1 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 1 | 10457 | -0.063 | -0.5002 | No |
| 38 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 10984 | -0.078 | -0.5296 | No |
| 39 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 11136 | -0.083 | -0.5301 | No |
| 40 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 11209 | -0.086 | -0.5243 | No |
| 41 | HDAC2 | HDAC2 Entrez, Source | histone deacetylase 2 | 11317 | -0.091 | -0.5204 | No |
| 42 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 11603 | -0.105 | -0.5282 | No |
| 43 | SMYD2 | SMYD2 Entrez, Source | SET and MYND domain containing 2 | 11621 | -0.105 | -0.5157 | No |
| 44 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 11669 | -0.108 | -0.5051 | No |
| 45 | CLU | CLU Entrez, Source | clusterin | 12046 | -0.128 | -0.5167 | No |
| 46 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12661 | -0.197 | -0.5372 | Yes |
| 47 | TXNIP | TXNIP Entrez, Source | thioredoxin interacting protein | 12699 | -0.205 | -0.5132 | Yes |
| 48 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | -0.4937 | Yes |
| 49 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 12920 | -0.259 | -0.4646 | Yes |
| 50 | DNAJB4 | DNAJB4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 4 | 13141 | -0.392 | -0.4299 | Yes |
| 51 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 13214 | -0.489 | -0.3714 | Yes |
| 52 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 13229 | -0.509 | -0.3060 | Yes |
| 53 | PEA15 | PEA15 Entrez, Source | phosphoprotein enriched in astrocytes 15 | 13253 | -0.561 | -0.2343 | Yes |
| 54 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13260 | -0.571 | -0.1601 | Yes |
| 55 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | 0.0005 | Yes |
