Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | SERINE_TYPE_ENDOPEPTIDASE_ACTIVITY |
| Enrichment Score (ES) | 0.6538979 |
| Normalized Enrichment Score (NES) | 1.9244902 |
| Nominal p-value | 0.0022522523 |
| FDR q-value | 0.0060300063 |
| FWER p-Value | 0.348 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | KLKB1 | KLKB1 Entrez, Source | kallikrein B, plasma (Fletcher factor) 1 | 29 | 0.564 | 0.1566 | Yes |
| 2 | PLG | PLG Entrez, Source | plasminogen | 81 | 0.434 | 0.2750 | Yes |
| 3 | F9 | F9 Entrez, Source | coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) | 289 | 0.270 | 0.3357 | Yes |
| 4 | F10 | F10 Entrez, Source | coagulation factor X | 342 | 0.251 | 0.4026 | Yes |
| 5 | PCSK6 | PCSK6 Entrez, Source | proprotein convertase subtilisin/kexin type 6 | 567 | 0.190 | 0.4393 | Yes |
| 6 | MASP2 | MASP2 Entrez, Source | mannan-binding lectin serine peptidase 2 | 718 | 0.171 | 0.4763 | Yes |
| 7 | PROC | PROC Entrez, Source | protein C (inactivator of coagulation factors Va and VIIIa) | 739 | 0.168 | 0.5223 | Yes |
| 8 | PRSS2 | PRSS2 Entrez, Source | protease, serine, 2 (trypsin 2) | 818 | 0.161 | 0.5617 | Yes |
| 9 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 1087 | 0.138 | 0.5804 | Yes |
| 10 | CFI | CFI Entrez, Source | complement factor I | 1261 | 0.126 | 0.6030 | Yes |
| 11 | CORIN | CORIN Entrez, Source | corin, serine peptidase | 1759 | 0.103 | 0.5946 | Yes |
| 12 | F12 | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 1808 | 0.101 | 0.6194 | Yes |
| 13 | HGFAC | HGFAC Entrez, Source | HGF activator | 2074 | 0.092 | 0.6253 | Yes |
| 14 | PCSK9 | PCSK9 Entrez, Source | proprotein convertase subtilisin/kexin type 9 | 2250 | 0.086 | 0.6365 | Yes |
| 15 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 2335 | 0.084 | 0.6539 | Yes |
| 16 | ACR | ACR Entrez, Source | acrosin | 4402 | 0.039 | 0.5098 | No |
| 17 | PREP | PREP Entrez, Source | prolyl endopeptidase | 4451 | 0.039 | 0.5171 | No |
| 18 | PCSK2 | PCSK2 Entrez, Source | proprotein convertase subtilisin/kexin type 2 | 5237 | 0.026 | 0.4654 | No |
| 19 | PRSS1 | PRSS1 Entrez, Source | protease, serine, 1 (trypsin 1) | 5744 | 0.018 | 0.4325 | No |
| 20 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 6121 | 0.012 | 0.4078 | No |
| 21 | GZMB | GZMB Entrez, Source | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 6123 | 0.012 | 0.4112 | No |
| 22 | TOR1A | TOR1A Entrez, Source | torsin family 1, member A (torsin A) | 7125 | -0.002 | 0.3366 | No |
| 23 | APEH | APEH Entrez, Source | N-acylaminoacyl-peptide hydrolase | 9171 | -0.035 | 0.1929 | No |
| 24 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 9195 | -0.035 | 0.2012 | No |
| 25 | KLK8 | KLK8 Entrez, Source | kallikrein 8 (neuropsin/ovasin) | 10533 | -0.065 | 0.1191 | No |
| 26 | HTRA2 | HTRA2 Entrez, Source | HtrA serine peptidase 2 | 11309 | -0.091 | 0.0865 | No |
| 27 | C1R | C1R Entrez, Source | complement component 1, r subcomponent | 11480 | -0.099 | 0.1015 | No |
| 28 | HTRA1 | HTRA1 Entrez, Source | HtrA serine peptidase 1 | 12167 | -0.136 | 0.0882 | No |
