Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | SERUM_FIBROBLAST_CELLCYCLE |
| Enrichment Score (ES) | -0.7365305 |
| Normalized Enrichment Score (NES) | -2.2948852 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 291 | 0.268 | 0.0068 | No |
| 2 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2527 | 0.079 | -0.1530 | No |
| 3 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 2566 | 0.078 | -0.1475 | No |
| 4 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 3790 | 0.050 | -0.2342 | No |
| 5 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4390 | 0.040 | -0.2750 | No |
| 6 | LYAR | LYAR Entrez, Source | - | 4619 | 0.036 | -0.2883 | No |
| 7 | CCNF | CCNF Entrez, Source | cyclin F | 4623 | 0.036 | -0.2847 | No |
| 8 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 4842 | 0.032 | -0.2977 | No |
| 9 | CIITA | CIITA Entrez, Source | class II, major histocompatibility complex, transactivator | 5468 | 0.022 | -0.3424 | No |
| 10 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5968 | 0.015 | -0.3784 | No |
| 11 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 6623 | 0.005 | -0.4270 | No |
| 12 | DONSON | DONSON Entrez, Source | downstream neighbor of SON | 6882 | 0.002 | -0.4463 | No |
| 13 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 8170 | -0.017 | -0.5413 | No |
| 14 | MAPK13 | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 8524 | -0.023 | -0.5653 | No |
| 15 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 8736 | -0.027 | -0.5783 | No |
| 16 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 9018 | -0.033 | -0.5960 | No |
| 17 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9129 | -0.035 | -0.6005 | No |
| 18 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 10798 | -0.072 | -0.7183 | No |
| 19 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 10999 | -0.079 | -0.7249 | No |
| 20 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 11154 | -0.084 | -0.7276 | Yes |
| 21 | TUBB2C | TUBB2C Entrez, Source | tubulin, beta 2C | 11159 | -0.084 | -0.7189 | Yes |
| 22 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 11249 | -0.088 | -0.7162 | Yes |
| 23 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 11402 | -0.095 | -0.7175 | Yes |
| 24 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 11411 | -0.095 | -0.7079 | Yes |
| 25 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 11676 | -0.108 | -0.7162 | Yes |
| 26 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11689 | -0.109 | -0.7055 | Yes |
| 27 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 11725 | -0.110 | -0.6963 | Yes |
| 28 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 11731 | -0.111 | -0.6848 | Yes |
| 29 | ABCC5 | ABCC5 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 11735 | -0.111 | -0.6732 | Yes |
| 30 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 11736 | -0.111 | -0.6614 | Yes |
| 31 | AURKA | AURKA Entrez, Source | aurora kinase A | 11917 | -0.119 | -0.6622 | Yes |
| 32 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12313 | -0.149 | -0.6759 | Yes |
| 33 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12449 | -0.164 | -0.6685 | Yes |
| 34 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12466 | -0.166 | -0.6520 | Yes |
| 35 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12607 | -0.185 | -0.6427 | Yes |
| 36 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 12752 | -0.214 | -0.6307 | Yes |
| 37 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 12767 | -0.216 | -0.6086 | Yes |
| 38 | CDCA8 | CDCA8 Entrez, Source | cell division cycle associated 8 | 12816 | -0.228 | -0.5878 | Yes |
| 39 | CDCA1 | CDCA1 Entrez, Source | cell division cycle associated 1 | 12849 | -0.236 | -0.5649 | Yes |
| 40 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12851 | -0.238 | -0.5395 | Yes |
| 41 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12949 | -0.272 | -0.5177 | Yes |
| 42 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12987 | -0.285 | -0.4900 | Yes |
| 43 | TUBB | TUBB Entrez, Source | tubulin, beta | 13001 | -0.292 | -0.4598 | Yes |
| 44 | TACC3 | TACC3 Entrez, Source | transforming, acidic coiled-coil containing protein 3 | 13008 | -0.294 | -0.4288 | Yes |
| 45 | HN1 | HN1 Entrez, Source | hematological and neurological expressed 1 | 13029 | -0.307 | -0.3975 | Yes |
| 46 | ADAMTS1 | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 13036 | -0.311 | -0.3647 | Yes |
| 47 | ANKRD10 | ANKRD10 Entrez, Source | ankyrin repeat domain 10 | 13047 | -0.318 | -0.3314 | Yes |
| 48 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 13078 | -0.337 | -0.2976 | Yes |
| 49 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13086 | -0.343 | -0.2614 | Yes |
| 50 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13193 | -0.458 | -0.2204 | Yes |
| 51 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.1602 | Yes |
| 52 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13280 | -0.659 | -0.0906 | Yes |
| 53 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13314 | -0.890 | 0.0021 | Yes |
