Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | SMITH_HCV_INDUCED_HCC_UP |
| Enrichment Score (ES) | 0.55911195 |
| Normalized Enrichment Score (NES) | 1.542093 |
| Nominal p-value | 0.033613447 |
| FDR q-value | 0.09639443 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 231 | 0.293 | 0.1484 | Yes |
| 2 | PMVK | PMVK Entrez, Source | phosphomevalonate kinase | 385 | 0.237 | 0.2710 | Yes |
| 3 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 462 | 0.212 | 0.3855 | Yes |
| 4 | SDC2 | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 817 | 0.161 | 0.4499 | Yes |
| 5 | AMACR | AMACR Entrez, Source | alpha-methylacyl-CoA racemase | 1143 | 0.134 | 0.5014 | Yes |
| 6 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 1308 | 0.124 | 0.5591 | Yes |
| 7 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4390 | 0.040 | 0.3503 | No |
| 8 | COPS5 | COPS5 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 5028 | 0.029 | 0.3187 | No |
| 9 | PXMP3 | PXMP3 Entrez, Source | peroxisomal membrane protein 3, 35kDa (Zellweger syndrome) | 5340 | 0.024 | 0.3090 | No |
| 10 | NCOA2 | NCOA2 Entrez, Source | nuclear receptor coactivator 2 | 5627 | 0.020 | 0.2988 | No |
| 11 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 5789 | 0.018 | 0.2966 | No |
| 12 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 6476 | 0.007 | 0.2489 | No |
| 13 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 6567 | 0.006 | 0.2453 | No |
| 14 | TBCE | TBCE Entrez, Source | tubulin-specific chaperone e | 6963 | 0.000 | 0.2158 | No |
| 15 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 8401 | -0.021 | 0.1201 | No |
| 16 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 8887 | -0.030 | 0.1005 | No |
| 17 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9129 | -0.035 | 0.1020 | No |
| 18 | GSTM4 | GSTM4 Entrez, Source | glutathione S-transferase M4 | 10178 | -0.056 | 0.0550 | No |
| 19 | ANXA7 | ANXA7 Entrez, Source | annexin A7 | 11132 | -0.083 | 0.0305 | No |
| 20 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 11757 | -0.112 | 0.0468 | No |
| 21 | IMPA2 | IMPA2 Entrez, Source | inositol(myo)-1(or 4)-monophosphatase 2 | 12041 | -0.127 | 0.0977 | No |
