Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | STRIATED_MUSCLE_CONTRACTION |
| Enrichment Score (ES) | -0.68722075 |
| Normalized Enrichment Score (NES) | -1.8554116 |
| Nominal p-value | 0.0036968577 |
| FDR q-value | 0.027916752 |
| FWER p-Value | 0.788 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | -0.0102 | No |
| 2 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 1352 | 0.121 | -0.0316 | No |
| 3 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 2130 | 0.090 | -0.0687 | No |
| 4 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 2763 | 0.072 | -0.0991 | No |
| 5 | TNNI1 | TNNI1 Entrez, Source | troponin I type 1 (skeletal, slow) | 3145 | 0.063 | -0.1127 | No |
| 6 | MYH6 /// MYH7 | 3344 | 0.059 | -0.1137 | No | ||
| 7 | TNNT1 | TNNT1 Entrez, Source | troponin T type 1 (skeletal, slow) | 3563 | 0.055 | -0.1172 | No |
| 8 | MYL2 | MYL2 Entrez, Source | myosin, light chain 2, regulatory, cardiac, slow | 3684 | 0.052 | -0.1139 | No |
| 9 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4891 | 0.031 | -0.1971 | No |
| 10 | TTN | TTN Entrez, Source | titin | 5994 | 0.014 | -0.2765 | No |
| 11 | MYBPC1 | MYBPC1 Entrez, Source | myosin binding protein C, slow type | 6054 | 0.013 | -0.2778 | No |
| 12 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 6538 | 0.006 | -0.3127 | No |
| 13 | MYH8 | MYH8 Entrez, Source | myosin, heavy chain 8, skeletal muscle, perinatal | 6915 | 0.001 | -0.3407 | No |
| 14 | TNNI2 | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 7460 | -0.007 | -0.3799 | No |
| 15 | MYH3 | MYH3 Entrez, Source | myosin, heavy chain 3, skeletal muscle, embryonic | 8743 | -0.027 | -0.4698 | No |
| 16 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 9345 | -0.039 | -0.5058 | No |
| 17 | DES | DES Entrez, Source | desmin | 11462 | -0.098 | -0.6416 | No |
| 18 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11968 | -0.123 | -0.6505 | Yes |
| 19 | TMOD1 | TMOD1 Entrez, Source | tropomodulin 1 | 12458 | -0.165 | -0.6484 | Yes |
| 20 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12537 | -0.177 | -0.6126 | Yes |
| 21 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 12793 | -0.222 | -0.5793 | Yes |
| 22 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12871 | -0.243 | -0.5279 | Yes |
| 23 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.4683 | Yes |
| 24 | VIM | VIM Entrez, Source | vimentin | 13227 | -0.506 | -0.3652 | Yes |
| 25 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
