Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON |
| Enrichment Score (ES) | -0.72848624 |
| Normalized Enrichment Score (NES) | -1.8914835 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021884331 |
| FWER p-Value | 0.624 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | -0.0150 | No |
| 2 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 804 | 0.162 | 0.0100 | No |
| 3 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 5403 | 0.023 | -0.3303 | No |
| 4 | ANK1 | ANK1 Entrez, Source | ankyrin 1, erythrocytic | 5713 | 0.019 | -0.3496 | No |
| 5 | GFAP | GFAP Entrez, Source | glial fibrillary acidic protein | 5960 | 0.015 | -0.3650 | No |
| 6 | SORBS3 | SORBS3 Entrez, Source | sorbin and SH3 domain containing 3 | 6233 | 0.011 | -0.3832 | No |
| 7 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 7686 | -0.010 | -0.4900 | No |
| 8 | HIP1 | HIP1 Entrez, Source | huntingtin interacting protein 1 | 9248 | -0.037 | -0.5996 | No |
| 9 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 9358 | -0.039 | -0.5997 | No |
| 10 | BFSP1 | BFSP1 Entrez, Source | beaded filament structural protein 1, filensin | 10212 | -0.057 | -0.6518 | No |
| 11 | ACTL7B | ACTL7B Entrez, Source | actin-like 7B | 10635 | -0.068 | -0.6694 | No |
| 12 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 10830 | -0.073 | -0.6687 | No |
| 13 | DES | DES Entrez, Source | desmin | 11462 | -0.098 | -0.6956 | Yes |
| 14 | ACTB | ACTB Entrez, Source | actin, beta | 11552 | -0.102 | -0.6811 | Yes |
| 15 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12086 | -0.130 | -0.6939 | Yes |
| 16 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 12548 | -0.178 | -0.6913 | Yes |
| 17 | DSP | DSP Entrez, Source | desmoplakin | 12648 | -0.194 | -0.6583 | Yes |
| 18 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12846 | -0.236 | -0.6240 | Yes |
| 19 | VIM | VIM Entrez, Source | vimentin | 13227 | -0.506 | -0.5471 | Yes |
| 20 | MSN | MSN Entrez, Source | moesin | 13329 | -1.080 | -0.3295 | Yes |
| 21 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
