Details for gene set STRUCTURAL_MOLECULE

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos
Phenotype	class.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in class	single_gel_72h
GeneSet	STRUCTURAL_MOLECULE_ACTIVITY
Enrichment Score (ES)	-0.570057
Normalized Enrichment Score (NES)	-2.0743093
Nominal p-value	0.0
FDR q-value	0.0022622119
FWER p-Value	0.042

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DMD	DMD Entrez, Source	dystrophin (muscular dystrophy, Duchenne and Becker types)	686	0.175	-0.0357	No
2	SPTBN4	SPTBN4 Entrez, Source	spectrin, beta, non-erythrocytic 4	804	0.162	-0.0295	No
3	RPL39	RPL39 Entrez, Source	ribosomal protein L39	960	0.148	-0.0275	No
4	MAL	MAL Entrez, Source	mal, T-cell differentiation protein	964	0.148	-0.0141	No
5	MGP	MGP Entrez, Source	matrix Gla protein	1003	0.144	-0.0036	No
6	MYH6	MYH6 Entrez, Source	myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)	1352	0.121	-0.0187	No
7	CHI3L1	CHI3L1 Entrez, Source	chitinase 3-like 1 (cartilage glycoprotein-39)	1617	0.108	-0.0287	No
8	MRPL12	MRPL12 Entrez, Source	mitochondrial ribosomal protein L12	1652	0.107	-0.0214	No
9	MATN1	MATN1 Entrez, Source	matrilin 1, cartilage matrix protein	1676	0.106	-0.0133	No
10	FBN2	FBN2 Entrez, Source	fibrillin 2 (congenital contractural arachnodactyly)	1754	0.103	-0.0096	No
11	MRPS7	MRPS7 Entrez, Source	mitochondrial ribosomal protein S7	1930	0.096	-0.0139	No
12	MYL3	MYL3 Entrez, Source	myosin, light chain 3, alkali; ventricular, skeletal, slow	2130	0.090	-0.0207	No
13	MYL2	MYL2 Entrez, Source	myosin, light chain 2, regulatory, cardiac, slow	3684	0.052	-0.1333	No
14	MYOC	MYOC Entrez, Source	myocilin, trabecular meshwork inducible glucocorticoid response	4241	0.042	-0.1715	No
15	MRPL23	MRPL23 Entrez, Source	mitochondrial ribosomal protein L23	4352	0.040	-0.1761	No
16	COL4A4	COL4A4 Entrez, Source	collagen, type IV, alpha 4	4358	0.040	-0.1728	No
17	SEPT4	SEPT4 Entrez, Source	septin 4	4795	0.033	-0.2027	No
18	DSPP	DSPP Entrez, Source	dentin sialophosphoprotein	4820	0.032	-0.2016	No
19	RPL35	RPL35 Entrez, Source	ribosomal protein L35	4821	0.032	-0.1986	No
20	MRPL41	MRPL41 Entrez, Source	mitochondrial ribosomal protein L41	4921	0.030	-0.2033	No
21	RPL21	RPL21 Entrez, Source	ribosomal protein L21	5125	0.027	-0.2161	No
22	SEPT5	SEPT5 Entrez, Source	septin 5	5197	0.026	-0.2190	No
23	RPS25	RPS25 Entrez, Source	ribosomal protein S25	5241	0.026	-0.2199	No
24	ADD3	ADD3 Entrez, Source	adducin 3 (gamma)	5403	0.023	-0.2300	No
25	PRELP	PRELP Entrez, Source	proline/arginine-rich end leucine-rich repeat protein	5708	0.019	-0.2512	No
26	ANK1	ANK1 Entrez, Source	ankyrin 1, erythrocytic	5713	0.019	-0.2498	No
27	TFPI2	TFPI2 Entrez, Source	tissue factor pathway inhibitor 2	5729	0.018	-0.2493	No
28	RPL4	RPL4 Entrez, Source	ribosomal protein L4	5769	0.018	-0.2506	No
29	RPL13	RPL13 Entrez, Source	ribosomal protein L13	5821	0.017	-0.2529	No
30	FBN1	FBN1 Entrez, Source	fibrillin 1	5918	0.015	-0.2587	No
31	GFAP	GFAP Entrez, Source	glial fibrillary acidic protein	5960	0.015	-0.2604	No
32	TTN	TTN Entrez, Source	titin	5994	0.014	-0.2616	No
33	MYBPC1	MYBPC1 Entrez, Source	myosin binding protein C, slow type	6054	0.013	-0.2648	No
34	RPL41	RPL41 Entrez, Source	ribosomal protein L41	6066	0.013	-0.2644	No
35	RPS18	RPS18 Entrez, Source	ribosomal protein S18	6172	0.012	-0.2713	No
36	SORBS3	SORBS3 Entrez, Source	sorbin and SH3 domain containing 3	6233	0.011	-0.2748	No
37	RPL14	RPL14 Entrez, Source	ribosomal protein L14	6253	0.010	-0.2753	No
38	RPS3A	RPS3A Entrez, Source	ribosomal protein S3A	6320	0.009	-0.2794	No
39	RPS13	RPS13 Entrez, Source	ribosomal protein S13	6324	0.009	-0.2788	No
40	RPL24	RPL24 Entrez, Source	ribosomal protein L24	6383	0.008	-0.2825	No
41	RPL37	RPL37 Entrez, Source	ribosomal protein L37	6404	0.008	-0.2833	No
42	RPS20	RPS20 Entrez, Source	ribosomal protein S20	6408	0.008	-0.2828	No
43	RPS26	RPS26 Entrez, Source	ribosomal protein S26	6430	0.007	-0.2837	No
44	RPS9	RPS9 Entrez, Source	ribosomal protein S9	6448	0.007	-0.2843	No
45	RPS12	RPS12 Entrez, Source	ribosomal protein S12	6467	0.007	-0.2851	No
46	RPL29	RPL29 Entrez, Source	ribosomal protein L29	6480	0.007	-0.2853	No
47	RPS17	RPS17 Entrez, Source	ribosomal protein S17	6495	0.006	-0.2858	No
48	RPS21	RPS21 Entrez, Source	ribosomal protein S21	6500	0.006	-0.2855	No
49	RPS29	RPS29 Entrez, Source	ribosomal protein S29	6511	0.006	-0.2857	No
50	RPS15	RPS15 Entrez, Source	ribosomal protein S15	6527	0.006	-0.2863	No
51	RPL18	RPL18 Entrez, Source	ribosomal protein L18	6533	0.006	-0.2861	No
52	RPS3	RPS3 Entrez, Source	ribosomal protein S3	6546	0.006	-0.2865	No
53	MEPE	MEPE Entrez, Source	matrix, extracellular phosphoglycoprotein with ASARM motif (bone)	6555	0.006	-0.2865	No
54	RPL28	RPL28 Entrez, Source	ribosomal protein L28	6566	0.006	-0.2868	No
55	RPS24	RPS24 Entrez, Source	ribosomal protein S24	6594	0.005	-0.2883	No
56	RPLP1	RPLP1 Entrez, Source	ribosomal protein, large, P1	6614	0.005	-0.2893	No
57	RPL7	RPL7 Entrez, Source	ribosomal protein L7	6616	0.005	-0.2889	No
58	RPL31	RPL31 Entrez, Source	ribosomal protein L31	6641	0.005	-0.2903	No
59	RPS14	RPS14 Entrez, Source	ribosomal protein S14	6720	0.004	-0.2958	No
60	MYH11	MYH11 Entrez, Source	myosin, heavy chain 11, smooth muscle	6721	0.004	-0.2955	No
61	RPS15A	RPS15A Entrez, Source	ribosomal protein S15a	6742	0.003	-0.2967	No
62	RPS23	RPS23 Entrez, Source	ribosomal protein S23	6845	0.002	-0.3042	No
63	RPS11	RPS11 Entrez, Source	ribosomal protein S11	6874	0.002	-0.3062	No
64	RPL27	RPL27 Entrez, Source	ribosomal protein L27	6890	0.001	-0.3072	No
65	RPL3	RPL3 Entrez, Source	ribosomal protein L3	6956	0.000	-0.3121	No
66	RPL30	RPL30 Entrez, Source	ribosomal protein L30	6985	-0.000	-0.3142	No
67	RPL8	RPL8 Entrez, Source	ribosomal protein L8	7041	-0.001	-0.3183	No
68	RPS10	RPS10 Entrez, Source	ribosomal protein S10	7076	-0.001	-0.3207	No
69	RPL26	RPL26 Entrez, Source	ribosomal protein L26	7117	-0.002	-0.3236	No
70	RPS8	RPS8 Entrez, Source	ribosomal protein S8	7121	-0.002	-0.3236	No
71	RPS2	RPS2 Entrez, Source	ribosomal protein S2	7135	-0.002	-0.3244	No
72	RPL9	RPL9 Entrez, Source	ribosomal protein L9	7163	-0.003	-0.3262	No
73	RPL6	RPL6 Entrez, Source	ribosomal protein L6	7233	-0.003	-0.3311	No
74	RPS27	RPS27 Entrez, Source	ribosomal protein S27 (metallopanstimulin 1)	7325	-0.005	-0.3375	No
75	RPL15	RPL15 Entrez, Source	ribosomal protein L15	7353	-0.005	-0.3391	No
76	MAPK8IP2	MAPK8IP2 Entrez, Source	mitogen-activated protein kinase 8 interacting protein 2	7361	-0.005	-0.3391	No
77	RPS5	RPS5 Entrez, Source	ribosomal protein S5	7405	-0.006	-0.3418	No
78	RPL13A	RPL13A Entrez, Source	ribosomal protein L13a	7446	-0.007	-0.3442	No
79	RPS4X	RPS4X Entrez, Source	ribosomal protein S4, X-linked	7462	-0.007	-0.3447	No
80	PLEC1	PLEC1 Entrez, Source	plectin 1, intermediate filament binding protein 500kDa	7482	-0.007	-0.3455	No
81	RPL5	RPL5 Entrez, Source	ribosomal protein L5	7524	-0.008	-0.3479	No
82	RPL22	RPL22 Entrez, Source	ribosomal protein L22	7541	-0.008	-0.3483	No
83	RPS19	RPS19 Entrez, Source	ribosomal protein S19	7575	-0.009	-0.3500	No
84	NEFL	NEFL Entrez, Source	neurofilament, light polypeptide 68kDa	7686	-0.010	-0.3574	No
85	MYBPH	MYBPH Entrez, Source	myosin binding protein H	7699	-0.010	-0.3573	No
86	RPS6	RPS6 Entrez, Source	ribosomal protein S6	7886	-0.013	-0.3702	No
87	ODF2	ODF2 Entrez, Source	outer dense fiber of sperm tails 2	7957	-0.014	-0.3741	No
88	RPL19	RPL19 Entrez, Source	ribosomal protein L19	7963	-0.014	-0.3732	No
89	MATR3	MATR3 Entrez, Source	matrin 3	8066	-0.016	-0.3794	No
90	SPAG4	SPAG4 Entrez, Source	sperm associated antigen 4	8137	-0.017	-0.3832	No
91	RPS16	RPS16 Entrez, Source	ribosomal protein S16	8144	-0.017	-0.3821	No
92	RPL11	RPL11 Entrez, Source	ribosomal protein L11	8243	-0.019	-0.3877	No
93	BFAR	BFAR Entrez, Source	bifunctional apoptosis regulator	8254	-0.019	-0.3867	No
94	IMPG2	IMPG2 Entrez, Source	interphotoreceptor matrix proteoglycan 2	8358	-0.021	-0.3926	No
95	CORO1A	CORO1A Entrez, Source	coronin, actin binding protein, 1A	8440	-0.022	-0.3966	No
96	MYH7	MYH7 Entrez, Source	myosin, heavy chain 7, cardiac muscle, beta	8532	-0.024	-0.4014	No
97	IVL	IVL Entrez, Source	involucrin	8669	-0.026	-0.4093	No
98	HIP1	HIP1 Entrez, Source	huntingtin interacting protein 1	9248	-0.037	-0.4496	No
99	MYOM1	MYOM1 Entrez, Source	myomesin 1 (skelemin) 185kDa	9345	-0.039	-0.4533	No
100	TUBG1	TUBG1 Entrez, Source	tubulin, gamma 1	9358	-0.039	-0.4506	No
101	BFSP1	BFSP1 Entrez, Source	beaded filament structural protein 1, filensin	10212	-0.057	-0.5099	No
102	IMPG1	IMPG1 Entrez, Source	interphotoreceptor matrix proteoglycan 1	10305	-0.059	-0.5113	No
103	ACTL7B	ACTL7B Entrez, Source	actin-like 7B	10635	-0.068	-0.5299	No
104	MAPT	MAPT Entrez, Source	microtubule-associated protein tau	10830	-0.073	-0.5379	No
105	MPZL1	MPZL1 Entrez, Source	myelin protein zero-like 1	11172	-0.085	-0.5558	No
106	FBLN2	FBLN2 Entrez, Source	fibulin 2	11361	-0.093	-0.5614	Yes
107	DES	DES Entrez, Source	desmin	11462	-0.098	-0.5599	Yes
108	ACTB	ACTB Entrez, Source	actin, beta	11552	-0.102	-0.5572	Yes
109	NUMA1	NUMA1 Entrez, Source	nuclear mitotic apparatus protein 1	11712	-0.110	-0.5591	Yes
110	COMP	COMP Entrez, Source	cartilage oligomeric matrix protein	11817	-0.115	-0.5564	Yes
111	ACTN3	ACTN3 Entrez, Source	actinin, alpha 3	11968	-0.123	-0.5563	Yes
112	ARPC5	ARPC5 Entrez, Source	actin related protein 2/3 complex, subunit 5, 16kDa	12086	-0.130	-0.5531	Yes
113	SEPT7	SEPT7 Entrez, Source	septin 7	12144	-0.134	-0.5450	Yes
114	SMTN	SMTN Entrez, Source	smoothelin	12423	-0.161	-0.5512	Yes
115	ARPC1B	ARPC1B Entrez, Source	actin related protein 2/3 complex, subunit 1B, 41kDa	12548	-0.178	-0.5440	Yes
116	DSP	DSP Entrez, Source	desmoplakin	12648	-0.194	-0.5335	Yes
117	ACTC1	ACTC1 Entrez, Source	actin, alpha, cardiac muscle 1	12692	-0.203	-0.5180	Yes
118	TPM4	TPM4 Entrez, Source	tropomyosin 4	12793	-0.222	-0.5050	Yes
119	SORBS2	SORBS2 Entrez, Source	sorbin and SH3 domain containing 2	12846	-0.236	-0.4871	Yes
120	EFEMP2	EFEMP2 Entrez, Source	EGF-containing fibulin-like extracellular matrix protein 2	12959	-0.276	-0.4700	Yes
121	TPM1	TPM1 Entrez, Source	tropomyosin 1 (alpha)	13011	-0.297	-0.4463	Yes
122	LAMC1	LAMC1 Entrez, Source	laminin, gamma 1 (formerly LAMB2)	13018	-0.300	-0.4190	Yes
123	LMNB1	LMNB1 Entrez, Source	lamin B1	13086	-0.343	-0.3923	Yes
124	VIM	VIM Entrez, Source	vimentin	13227	-0.506	-0.3561	Yes
125	MSN	MSN Entrez, Source	moesin	13329	-1.080	-0.2637	Yes
126	ANXA1	ANXA1 Entrez, Source	annexin A1	13336	-1.272	-0.1464	Yes
127	ACTA1	ACTA1 Entrez, Source	actin, alpha 1, skeletal muscle	13340	-1.586	0.0002	Yes