Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | TGFBETA_EARLY_UP |
| Enrichment Score (ES) | -0.6847922 |
| Normalized Enrichment Score (NES) | -2.004085 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006406323 |
| FWER p-Value | 0.158 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 473 | 0.209 | -0.0003 | No |
| 2 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 1644 | 0.107 | -0.0703 | No |
| 3 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 2212 | 0.088 | -0.0981 | No |
| 4 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 2800 | 0.071 | -0.1302 | No |
| 5 | DVL1 | DVL1 Entrez, Source | dishevelled, dsh homolog 1 (Drosophila) | 2814 | 0.071 | -0.1192 | No |
| 6 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 3018 | 0.066 | -0.1233 | No |
| 7 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 3728 | 0.051 | -0.1680 | No |
| 8 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 3989 | 0.047 | -0.1797 | No |
| 9 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4057 | 0.045 | -0.1771 | No |
| 10 | WNT2B | WNT2B Entrez, Source | wingless-type MMTV integration site family, member 2B | 4771 | 0.033 | -0.2252 | No |
| 11 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 5548 | 0.021 | -0.2799 | No |
| 12 | NID1 | NID1 Entrez, Source | nidogen 1 | 7761 | -0.011 | -0.4443 | No |
| 13 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 8051 | -0.016 | -0.4634 | No |
| 14 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 8281 | -0.020 | -0.4773 | No |
| 15 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 8308 | -0.020 | -0.4759 | No |
| 16 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 8656 | -0.026 | -0.4977 | No |
| 17 | LRRC17 | LRRC17 Entrez, Source | leucine rich repeat containing 17 | 8928 | -0.031 | -0.5129 | No |
| 18 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 8953 | -0.031 | -0.5094 | No |
| 19 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 9146 | -0.035 | -0.5180 | No |
| 20 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 9287 | -0.038 | -0.5222 | No |
| 21 | RHOG | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 9303 | -0.038 | -0.5169 | No |
| 22 | CDH6 | CDH6 Entrez, Source | cadherin 6, type 2, K-cadherin (fetal kidney) | 9721 | -0.046 | -0.5405 | No |
| 23 | FN1 | FN1 Entrez, Source | fibronectin 1 | 10062 | -0.053 | -0.5571 | No |
| 24 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 11466 | -0.098 | -0.6460 | No |
| 25 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11527 | -0.101 | -0.6336 | No |
| 26 | JUP | JUP Entrez, Source | junction plakoglobin | 12003 | -0.125 | -0.6482 | No |
| 27 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 12491 | -0.169 | -0.6563 | Yes |
| 28 | RND3 | RND3 Entrez, Source | Rho family GTPase 3 | 12492 | -0.169 | -0.6279 | Yes |
| 29 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12541 | -0.177 | -0.6016 | Yes |
| 30 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12629 | -0.189 | -0.5763 | Yes |
| 31 | PXN | PXN Entrez, Source | paxillin | 12740 | -0.211 | -0.5490 | Yes |
| 32 | ZYX | ZYX Entrez, Source | zyxin | 12928 | -0.262 | -0.5190 | Yes |
| 33 | RHOQ | RHOQ Entrez, Source | ras homolog gene family, member Q | 13120 | -0.369 | -0.4713 | Yes |
| 34 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13125 | -0.378 | -0.4080 | Yes |
| 35 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13174 | -0.431 | -0.3390 | Yes |
| 36 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13193 | -0.458 | -0.2632 | Yes |
| 37 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13198 | -0.463 | -0.1857 | Yes |
| 38 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13330 | -1.167 | 0.0009 | Yes |
