Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | TRANSFERASE_ACTIVITY__TRANSFERRING_ONE_CARBON_GROUPS |
| Enrichment Score (ES) | 0.5708768 |
| Normalized Enrichment Score (NES) | 1.5890436 |
| Nominal p-value | 0.01871102 |
| FDR q-value | 0.07207672 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PEMT | PEMT Entrez, Source | phosphatidylethanolamine N-methyltransferase | 8 | 0.798 | 0.2607 | Yes |
| 2 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 106 | 0.415 | 0.3892 | Yes |
| 3 | AS3MT | AS3MT Entrez, Source | arsenic (+3 oxidation state) methyltransferase | 242 | 0.289 | 0.4736 | Yes |
| 4 | GAMT | GAMT Entrez, Source | guanidinoacetate N-methyltransferase | 295 | 0.267 | 0.5572 | Yes |
| 5 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 816 | 0.161 | 0.5709 | Yes |
| 6 | COQ3 | COQ3 Entrez, Source | coenzyme Q3 homolog, methyltransferase (S. cerevisiae) | 1406 | 0.118 | 0.5654 | No |
| 7 | DNMT3B | DNMT3B Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 beta | 2369 | 0.083 | 0.5206 | No |
| 8 | GART | GART Entrez, Source | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | 2994 | 0.067 | 0.4956 | No |
| 9 | PNMT | PNMT Entrez, Source | phenylethanolamine N-methyltransferase | 3761 | 0.051 | 0.4546 | No |
| 10 | PCMT1 | PCMT1 Entrez, Source | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 4670 | 0.035 | 0.3979 | No |
| 11 | LCMT1 | LCMT1 Entrez, Source | leucine carboxyl methyltransferase 1 | 5536 | 0.021 | 0.3399 | No |
| 12 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 6816 | 0.002 | 0.2447 | No |
| 13 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 9156 | -0.035 | 0.0805 | No |
| 14 | CARM1 | CARM1 Entrez, Source | coactivator-associated arginine methyltransferase 1 | 9227 | -0.036 | 0.0872 | No |
| 15 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 9405 | -0.040 | 0.0869 | No |
| 16 | ATIC | ATIC Entrez, Source | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 9649 | -0.045 | 0.0832 | No |
| 17 | PRMT1 | PRMT1 Entrez, Source | protein arginine methyltransferase 1 | 10787 | -0.072 | 0.0215 | No |
| 18 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 11580 | -0.103 | -0.0041 | No |
| 19 | FBXO11 | FBXO11 Entrez, Source | F-box protein 11 | 11862 | -0.117 | 0.0131 | No |
| 20 | MGMT | MGMT Entrez, Source | O-6-methylguanine-DNA methyltransferase | 11936 | -0.121 | 0.0472 | No |
| 21 | TPMT | TPMT Entrez, Source | thiopurine S-methyltransferase | 12545 | -0.178 | 0.0598 | No |
