Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | TRYPTOPHAN_METABOLISM |
| Enrichment Score (ES) | 0.7439213 |
| Normalized Enrichment Score (NES) | 2.3122852 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 6 | 0.908 | 0.1473 | Yes |
| 2 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 24 | 0.594 | 0.2426 | Yes |
| 3 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 64 | 0.478 | 0.3175 | Yes |
| 4 | HAAO | HAAO Entrez, Source | 3-hydroxyanthranilate 3,4-dioxygenase | 120 | 0.390 | 0.3769 | Yes |
| 5 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 144 | 0.362 | 0.4340 | Yes |
| 6 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 201 | 0.309 | 0.4801 | Yes |
| 7 | ACMSD | ACMSD Entrez, Source | aminocarboxymuconate semialdehyde decarboxylase | 208 | 0.306 | 0.5295 | Yes |
| 8 | CAT | CAT Entrez, Source | catalase | 290 | 0.269 | 0.5672 | Yes |
| 9 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 358 | 0.245 | 0.6021 | Yes |
| 10 | CYP51A1 | CYP51A1 Entrez, Source | cytochrome P450, family 51, subfamily A, polypeptide 1 | 366 | 0.244 | 0.6412 | Yes |
| 11 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 390 | 0.235 | 0.6777 | Yes |
| 12 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 560 | 0.191 | 0.6960 | Yes |
| 13 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 633 | 0.182 | 0.7202 | Yes |
| 14 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 695 | 0.174 | 0.7439 | Yes |
| 15 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 1369 | 0.121 | 0.7130 | No |
| 16 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 1779 | 0.102 | 0.6988 | No |
| 17 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 2174 | 0.089 | 0.6837 | No |
| 18 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 2239 | 0.087 | 0.6930 | No |
| 19 | AANAT | AANAT Entrez, Source | arylalkylamine N-acetyltransferase | 2341 | 0.084 | 0.6990 | No |
| 20 | CYP1A1 | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 2351 | 0.084 | 0.7120 | No |
| 21 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 2897 | 0.069 | 0.6823 | No |
| 22 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 3427 | 0.057 | 0.6518 | No |
| 23 | TPH1 | TPH1 Entrez, Source | tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) | 4036 | 0.046 | 0.6136 | No |
| 24 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 4819 | 0.032 | 0.5600 | No |
| 25 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 5218 | 0.026 | 0.5344 | No |
| 26 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 5520 | 0.021 | 0.5152 | No |
| 27 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6175 | 0.012 | 0.4680 | No |
| 28 | ASMT | ASMT Entrez, Source | acetylserotonin O-methyltransferase | 6518 | 0.006 | 0.4433 | No |
| 29 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 6596 | 0.005 | 0.4384 | No |
| 30 | CYP2C9 | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 6753 | 0.003 | 0.4271 | No |
| 31 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 8401 | -0.021 | 0.3068 | No |
| 32 | SDS | SDS Entrez, Source | serine dehydratase | 8683 | -0.026 | 0.2900 | No |
| 33 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 9012 | -0.032 | 0.2706 | No |
| 34 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 9824 | -0.048 | 0.2175 | No |
| 35 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 10311 | -0.059 | 0.1906 | No |
| 36 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 10674 | -0.069 | 0.1747 | No |
| 37 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 10801 | -0.073 | 0.1770 | No |
| 38 | CYP4B1 | CYP4B1 Entrez, Source | cytochrome P450, family 4, subfamily B, polypeptide 1 | 11195 | -0.086 | 0.1614 | No |
