Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | TYROSINE_METABOLISM |
| Enrichment Score (ES) | 0.68699574 |
| Normalized Enrichment Score (NES) | 1.9308501 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0058417516 |
| FWER p-Value | 0.328 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 24 | 0.594 | 0.1402 | Yes |
| 2 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 53 | 0.495 | 0.2565 | Yes |
| 3 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.3487 | Yes |
| 4 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 126 | 0.385 | 0.4398 | Yes |
| 5 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 163 | 0.343 | 0.5191 | Yes |
| 6 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 201 | 0.309 | 0.5902 | Yes |
| 7 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 219 | 0.299 | 0.6606 | Yes |
| 8 | TAT | TAT Entrez, Source | tyrosine aminotransferase | 674 | 0.176 | 0.6687 | Yes |
| 9 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 1116 | 0.136 | 0.6681 | Yes |
| 10 | COMT | COMT Entrez, Source | catechol-O-methyltransferase | 1267 | 0.126 | 0.6870 | Yes |
| 11 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 1779 | 0.102 | 0.6730 | No |
| 12 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 2053 | 0.092 | 0.6746 | No |
| 13 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 2897 | 0.069 | 0.6278 | No |
| 14 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 3427 | 0.057 | 0.6018 | No |
| 15 | PNMT | PNMT Entrez, Source | phenylethanolamine N-methyltransferase | 3761 | 0.051 | 0.5889 | No |
| 16 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 3800 | 0.050 | 0.5980 | No |
| 17 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4383 | 0.040 | 0.5638 | No |
| 18 | TH | TH Entrez, Source | tyrosine hydroxylase | 5089 | 0.028 | 0.5175 | No |
| 19 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 5916 | 0.015 | 0.4592 | No |
| 20 | DBH | DBH Entrez, Source | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 8258 | -0.019 | 0.2881 | No |
| 21 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 8401 | -0.021 | 0.2825 | No |
| 22 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 9824 | -0.048 | 0.1873 | No |
| 23 | TPO | TPO Entrez, Source | thyroid peroxidase | 11532 | -0.101 | 0.0833 | No |
| 24 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 12784 | -0.220 | 0.0419 | No |
