Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | UEDA_MOUSE_LIVER |
| Enrichment Score (ES) | 0.4961991 |
| Normalized Enrichment Score (NES) | 1.8742276 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0085714 |
| FWER p-Value | 0.59 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 37 | 0.535 | 0.0304 | Yes |
| 2 | AQP9 | AQP9 Entrez, Source | aquaporin 9 | 38 | 0.530 | 0.0634 | Yes |
| 3 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 71 | 0.452 | 0.0891 | Yes |
| 4 | ELOVL6 | ELOVL6 Entrez, Source | ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 83 | 0.433 | 0.1152 | Yes |
| 5 | FASN | FASN Entrez, Source | fatty acid synthase | 101 | 0.417 | 0.1398 | Yes |
| 6 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 136 | 0.372 | 0.1604 | Yes |
| 7 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 178 | 0.330 | 0.1777 | Yes |
| 8 | ASL | ASL Entrez, Source | argininosuccinate lyase | 183 | 0.323 | 0.1975 | Yes |
| 9 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 195 | 0.312 | 0.2161 | Yes |
| 10 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 203 | 0.308 | 0.2347 | Yes |
| 11 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 211 | 0.305 | 0.2531 | Yes |
| 12 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 322 | 0.259 | 0.2609 | Yes |
| 13 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 328 | 0.257 | 0.2765 | Yes |
| 14 | FOXA3 | FOXA3 Entrez, Source | forkhead box A3 | 340 | 0.252 | 0.2913 | Yes |
| 15 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 362 | 0.244 | 0.3049 | Yes |
| 16 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 419 | 0.224 | 0.3146 | Yes |
| 17 | AK3L1 | AK3L1 Entrez, Source | adenylate kinase 3-like 1 | 442 | 0.218 | 0.3265 | Yes |
| 18 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 462 | 0.212 | 0.3383 | Yes |
| 19 | ERBB3 | ERBB3 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 588 | 0.187 | 0.3405 | Yes |
| 20 | CYP8B1 | CYP8B1 Entrez, Source | cytochrome P450, family 8, subfamily B, polypeptide 1 | 594 | 0.187 | 0.3517 | Yes |
| 21 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 599 | 0.186 | 0.3630 | Yes |
| 22 | FBXO8 | FBXO8 Entrez, Source | F-box protein 8 | 604 | 0.186 | 0.3742 | Yes |
| 23 | SERPINF2 | SERPINF2 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 607 | 0.185 | 0.3856 | Yes |
| 24 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 613 | 0.184 | 0.3967 | Yes |
| 25 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 632 | 0.182 | 0.4066 | Yes |
| 26 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 693 | 0.174 | 0.4129 | Yes |
| 27 | CRY1 | CRY1 Entrez, Source | cryptochrome 1 (photolyase-like) | 734 | 0.169 | 0.4203 | Yes |
| 28 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 852 | 0.158 | 0.4213 | Yes |
| 29 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 884 | 0.154 | 0.4285 | Yes |
| 30 | TMEM150 | TMEM150 Entrez, Source | transmembrane protein 150 | 885 | 0.154 | 0.4381 | Yes |
| 31 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 965 | 0.148 | 0.4413 | Yes |
| 32 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 979 | 0.147 | 0.4494 | Yes |
| 33 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 1030 | 0.142 | 0.4545 | Yes |
| 34 | LGALS9 | LGALS9 Entrez, Source | lectin, galactoside-binding, soluble, 9 (galectin 9) | 1031 | 0.142 | 0.4633 | Yes |
| 35 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 1046 | 0.140 | 0.4710 | Yes |
| 36 | FKBP4 | FKBP4 Entrez, Source | FK506 binding protein 4, 59kDa | 1164 | 0.132 | 0.4704 | Yes |
| 37 | CES3 | CES3 Entrez, Source | carboxylesterase 3 (brain) | 1183 | 0.131 | 0.4772 | Yes |
| 38 | PDIA4 | PDIA4 Entrez, Source | protein disulfide isomerase family A, member 4 | 1197 | 0.130 | 0.4843 | Yes |
| 39 | ARL6IP2 | ARL6IP2 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 2 | 1204 | 0.130 | 0.4919 | Yes |
| 40 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 1252 | 0.127 | 0.4962 | Yes |
| 41 | KLF9 | KLF9 Entrez, Source | Kruppel-like factor 9 | 1556 | 0.110 | 0.4802 | No |
| 42 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 1697 | 0.105 | 0.4761 | No |
| 43 | TSPAN4 | TSPAN4 Entrez, Source | tetraspanin 4 | 1713 | 0.105 | 0.4815 | No |
| 44 | MKNK2 | MKNK2 Entrez, Source | MAP kinase interacting serine/threonine kinase 2 | 1755 | 0.103 | 0.4848 | No |
| 45 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 1814 | 0.101 | 0.4867 | No |
| 46 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 2353 | 0.084 | 0.4512 | No |
| 47 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 2453 | 0.081 | 0.4488 | No |
| 48 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 2459 | 0.081 | 0.4534 | No |
| 49 | PER2 | PER2 Entrez, Source | period homolog 2 (Drosophila) | 2513 | 0.079 | 0.4544 | No |
| 50 | CHKA | CHKA Entrez, Source | choline kinase alpha | 2612 | 0.076 | 0.4517 | No |
| 51 | ST3GAL5 | ST3GAL5 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3413 | 0.058 | 0.3948 | No |
| 52 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 3800 | 0.050 | 0.3688 | No |
| 53 | DNAJB11 | DNAJB11 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 11 | 3986 | 0.047 | 0.3577 | No |
| 54 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 4020 | 0.046 | 0.3580 | No |
| 55 | TARS | TARS Entrez, Source | threonyl-tRNA synthetase | 4081 | 0.045 | 0.3563 | No |
| 56 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 4177 | 0.043 | 0.3518 | No |
| 57 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 4353 | 0.040 | 0.3411 | No |
| 58 | CD9 | CD9 Entrez, Source | CD9 molecule | 4896 | 0.031 | 0.3021 | No |
| 59 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4996 | 0.029 | 0.2964 | No |
| 60 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 5361 | 0.024 | 0.2704 | No |
| 61 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 5391 | 0.023 | 0.2696 | No |
| 62 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 5562 | 0.021 | 0.2581 | No |
| 63 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 5729 | 0.018 | 0.2467 | No |
| 64 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 5815 | 0.017 | 0.2413 | No |
| 65 | SQSTM1 | SQSTM1 Entrez, Source | sequestosome 1 | 6130 | 0.012 | 0.2184 | No |
| 66 | HES6 | HES6 Entrez, Source | hairy and enhancer of split 6 (Drosophila) | 6341 | 0.009 | 0.2031 | No |
| 67 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 6773 | 0.003 | 0.1707 | No |
| 68 | BRI3 | BRI3 Entrez, Source | brain protein I3 | 6885 | 0.002 | 0.1624 | No |
| 69 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 7124 | -0.002 | 0.1445 | No |
| 70 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 7472 | -0.007 | 0.1188 | No |
| 71 | NR1D2 | NR1D2 Entrez, Source | nuclear receptor subfamily 1, group D, member 2 | 7779 | -0.012 | 0.0964 | No |
| 72 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 7875 | -0.013 | 0.0900 | No |
| 73 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 8154 | -0.017 | 0.0701 | No |
| 74 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 8284 | -0.020 | 0.0616 | No |
| 75 | ABCB4 | ABCB4 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | 8306 | -0.020 | 0.0612 | No |
| 76 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 8491 | -0.023 | 0.0487 | No |
| 77 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 9325 | -0.038 | -0.0118 | No |
| 78 | DAZAP2 | DAZAP2 Entrez, Source | DAZ associated protein 2 | 9364 | -0.039 | -0.0123 | No |
| 79 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 9785 | -0.048 | -0.0411 | No |
| 80 | CLDN1 | CLDN1 Entrez, Source | claudin 1 | 10094 | -0.054 | -0.0610 | No |
| 81 | PCAF | PCAF Entrez, Source | p300/CBP-associated factor | 10191 | -0.056 | -0.0647 | No |
| 82 | PNRC1 | PNRC1 Entrez, Source | proline-rich nuclear receptor coactivator 1 | 10356 | -0.060 | -0.0734 | No |
| 83 | THRAP3 | THRAP3 Entrez, Source | thyroid hormone receptor associated protein 3 | 10383 | -0.061 | -0.0715 | No |
| 84 | LSR | LSR Entrez, Source | lipolysis stimulated lipoprotein receptor | 10501 | -0.064 | -0.0764 | No |
| 85 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 10691 | -0.070 | -0.0863 | No |
| 86 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 10705 | -0.070 | -0.0830 | No |
| 87 | MESDC2 | MESDC2 Entrez, Source | mesoderm development candidate 2 | 10843 | -0.074 | -0.0887 | No |
| 88 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 10871 | -0.074 | -0.0862 | No |
| 89 | MGEA5 | MGEA5 Entrez, Source | meningioma expressed antigen 5 (hyaluronidase) | 11364 | -0.093 | -0.1175 | No |
| 90 | FDX1 | FDX1 Entrez, Source | ferredoxin 1 | 11489 | -0.099 | -0.1207 | No |
| 91 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 11553 | -0.102 | -0.1192 | No |
| 92 | SLC9A3R1 | SLC9A3R1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 11571 | -0.103 | -0.1141 | No |
| 93 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 11654 | -0.107 | -0.1136 | No |
| 94 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12310 | -0.149 | -0.1538 | No |
| 95 | FGF1 | FGF1 Entrez, Source | fibroblast growth factor 1 (acidic) | 12527 | -0.175 | -0.1593 | No |
| 96 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 12574 | -0.181 | -0.1515 | No |
| 97 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12680 | -0.201 | -0.1470 | No |
| 98 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 12691 | -0.203 | -0.1351 | No |
| 99 | CD47 | CD47 Entrez, Source | CD47 molecule | 12700 | -0.205 | -0.1230 | No |
| 100 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 12937 | -0.264 | -0.1244 | No |
| 101 | TUBB | TUBB Entrez, Source | tubulin, beta | 13001 | -0.292 | -0.1110 | No |
| 102 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 13081 | -0.341 | -0.0958 | No |
| 103 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 13087 | -0.346 | -0.0747 | No |
| 104 | AVPR1A | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 13117 | -0.366 | -0.0541 | No |
| 105 | LMO7 | LMO7 Entrez, Source | LIM domain 7 | 13209 | -0.477 | -0.0314 | No |
| 106 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13282 | -0.665 | 0.0045 | No |
