Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | UVC_TTD_4HR_DN |
| Enrichment Score (ES) | -0.5296052 |
| Normalized Enrichment Score (NES) | -1.9078138 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.019221434 |
| FWER p-Value | 0.544 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 329 | 0.257 | -0.0058 | No |
| 2 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 420 | 0.224 | 0.0040 | No |
| 3 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 613 | 0.184 | 0.0031 | No |
| 4 | CRY1 | CRY1 Entrez, Source | cryptochrome 1 (photolyase-like) | 734 | 0.169 | 0.0066 | No |
| 5 | PRKCBP1 | PRKCBP1 Entrez, Source | protein kinase C binding protein 1 | 932 | 0.150 | 0.0028 | No |
| 6 | PTPN2 | PTPN2 Entrez, Source | protein tyrosine phosphatase, non-receptor type 2 | 1107 | 0.137 | -0.0002 | No |
| 7 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 1449 | 0.116 | -0.0174 | No |
| 8 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 1483 | 0.114 | -0.0115 | No |
| 9 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 1693 | 0.105 | -0.0195 | No |
| 10 | GULP1 | GULP1 Entrez, Source | GULP, engulfment adaptor PTB domain containing 1 | 1862 | 0.099 | -0.0249 | No |
| 11 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 1965 | 0.095 | -0.0255 | No |
| 12 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 2656 | 0.075 | -0.0722 | No |
| 13 | HOMER1 | HOMER1 Entrez, Source | homer homolog 1 (Drosophila) | 2707 | 0.073 | -0.0705 | No |
| 14 | PTPN12 | PTPN12 Entrez, Source | protein tyrosine phosphatase, non-receptor type 12 | 3086 | 0.065 | -0.0943 | No |
| 15 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 3182 | 0.063 | -0.0969 | No |
| 16 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 3374 | 0.059 | -0.1070 | No |
| 17 | PEX14 | PEX14 Entrez, Source | peroxisomal biogenesis factor 14 | 3565 | 0.054 | -0.1173 | No |
| 18 | RBM16 | RBM16 Entrez, Source | RNA binding motif protein 16 | 3735 | 0.051 | -0.1263 | No |
| 19 | TMEM23 | TMEM23 Entrez, Source | transmembrane protein 23 | 3767 | 0.050 | -0.1249 | No |
| 20 | ZHX3 | ZHX3 Entrez, Source | zinc fingers and homeoboxes 3 | 3978 | 0.047 | -0.1373 | No |
| 21 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 3999 | 0.046 | -0.1354 | No |
| 22 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 4030 | 0.046 | -0.1343 | No |
| 23 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | -0.1346 | No |
| 24 | EDG2 | EDG2 Entrez, Source | endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 | 4234 | 0.042 | -0.1431 | No |
| 25 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 4822 | 0.032 | -0.1851 | No |
| 26 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 4948 | 0.030 | -0.1924 | No |
| 27 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 5439 | 0.023 | -0.2278 | No |
| 28 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 5490 | 0.022 | -0.2299 | No |
| 29 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 5502 | 0.022 | -0.2291 | No |
| 30 | CEP350 | CEP350 Entrez, Source | centrosomal protein 350kDa | 5735 | 0.018 | -0.2453 | No |
| 31 | RBM39 | RBM39 Entrez, Source | RNA binding motif protein 39 | 5798 | 0.017 | -0.2487 | No |
| 32 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 5856 | 0.016 | -0.2518 | No |
| 33 | ARNT2 | ARNT2 Entrez, Source | aryl-hydrocarbon receptor nuclear translocator 2 | 5871 | 0.016 | -0.2517 | No |
| 34 | STK39 | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 5922 | 0.015 | -0.2543 | No |
| 35 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 6006 | 0.014 | -0.2596 | No |
| 36 | RSN | RSN Entrez, Source | restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) | 6102 | 0.013 | -0.2658 | No |
| 37 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 6114 | 0.013 | -0.2657 | No |
| 38 | TSPAN5 | TSPAN5 Entrez, Source | tetraspanin 5 | 6410 | 0.008 | -0.2875 | No |
| 39 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6703 | 0.004 | -0.3093 | No |
| 40 | MGAT5 | MGAT5 Entrez, Source | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 6814 | 0.002 | -0.3174 | No |
| 41 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 6904 | 0.001 | -0.3241 | No |
| 42 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7050 | -0.001 | -0.3350 | No |
| 43 | ZRF1 | ZRF1 Entrez, Source | zuotin related factor 1 | 7203 | -0.003 | -0.3462 | No |
| 44 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 7480 | -0.007 | -0.3666 | No |
| 45 | SLC4A7 | SLC4A7 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 7486 | -0.007 | -0.3664 | No |
| 46 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 7625 | -0.009 | -0.3762 | No |
| 47 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 7659 | -0.010 | -0.3779 | No |
| 48 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 7754 | -0.011 | -0.3842 | No |
| 49 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 7793 | -0.012 | -0.3862 | No |
| 50 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 7962 | -0.014 | -0.3978 | No |
| 51 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 7984 | -0.015 | -0.3983 | No |
| 52 | RGS7 | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 7991 | -0.015 | -0.3977 | No |
| 53 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 8340 | -0.020 | -0.4225 | No |
| 54 | AFAP | AFAP Entrez, Source | - | 8351 | -0.021 | -0.4217 | No |
| 55 | PARG | PARG Entrez, Source | poly (ADP-ribose) glycohydrolase | 8393 | -0.021 | -0.4233 | No |
| 56 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 8561 | -0.024 | -0.4341 | No |
| 57 | OGT | OGT Entrez, Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 8678 | -0.026 | -0.4409 | No |
| 58 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 8693 | -0.026 | -0.4401 | No |
| 59 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 8798 | -0.028 | -0.4458 | No |
| 60 | SIPA1L1 | SIPA1L1 Entrez, Source | signal-induced proliferation-associated 1 like 1 | 8860 | -0.029 | -0.4483 | No |
| 61 | PKN2 | PKN2 Entrez, Source | protein kinase N2 | 8882 | -0.030 | -0.4477 | No |
| 62 | ATF2 | ATF2 Entrez, Source | activating transcription factor 2 | 9097 | -0.034 | -0.4614 | No |
| 63 | MARCH7 | MARCH7 Entrez, Source | membrane-associated ring finger (C3HC4) 7 | 9196 | -0.036 | -0.4661 | No |
| 64 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 9229 | -0.036 | -0.4659 | No |
| 65 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 9417 | -0.040 | -0.4770 | No |
| 66 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 9459 | -0.041 | -0.4771 | No |
| 67 | ARIH1 | ARIH1 Entrez, Source | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 9532 | -0.042 | -0.4794 | No |
| 68 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 9534 | -0.042 | -0.4764 | No |
| 69 | TCF12 | TCF12 Entrez, Source | transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) | 9690 | -0.045 | -0.4847 | No |
| 70 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 9831 | -0.048 | -0.4917 | No |
| 71 | WDR7 | WDR7 Entrez, Source | WD repeat domain 7 | 9952 | -0.051 | -0.4970 | No |
| 72 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 9998 | -0.052 | -0.4966 | No |
| 73 | PUM2 | PUM2 Entrez, Source | pumilio homolog 2 (Drosophila) | 10034 | -0.053 | -0.4953 | No |
| 74 | CNOT4 | CNOT4 Entrez, Source | CCR4-NOT transcription complex, subunit 4 | 10146 | -0.055 | -0.4996 | No |
| 75 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 10279 | -0.058 | -0.5053 | No |
| 76 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 10310 | -0.059 | -0.5031 | No |
| 77 | SLIT1 | SLIT1 Entrez, Source | slit homolog 1 (Drosophila) | 10513 | -0.064 | -0.5136 | No |
| 78 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 10642 | -0.068 | -0.5183 | No |
| 79 | PPP2R2A | PPP2R2A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 10720 | -0.070 | -0.5189 | No |
| 80 | MTMR3 | MTMR3 Entrez, Source | myotubularin related protein 3 | 10836 | -0.073 | -0.5221 | No |
| 81 | CNOT2 | CNOT2 Entrez, Source | CCR4-NOT transcription complex, subunit 2 | 10885 | -0.075 | -0.5202 | No |
| 82 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 10891 | -0.075 | -0.5151 | No |
| 83 | XRCC4 | XRCC4 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 4 | 11084 | -0.081 | -0.5236 | Yes |
| 84 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 11105 | -0.082 | -0.5190 | Yes |
| 85 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 11154 | -0.084 | -0.5164 | Yes |
| 86 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 11211 | -0.086 | -0.5143 | Yes |
| 87 | SYNJ2 | SYNJ2 Entrez, Source | synaptojanin 2 | 11227 | -0.087 | -0.5090 | Yes |
| 88 | STRN3 | STRN3 Entrez, Source | striatin, calmodulin binding protein 3 | 11294 | -0.090 | -0.5073 | Yes |
| 89 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 11431 | -0.096 | -0.5105 | Yes |
| 90 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11474 | -0.098 | -0.5063 | Yes |
| 91 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 11555 | -0.102 | -0.5048 | Yes |
| 92 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 11731 | -0.111 | -0.5099 | Yes |
| 93 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 11749 | -0.111 | -0.5029 | Yes |
| 94 | KIF2A | KIF2A Entrez, Source | kinesin heavy chain member 2A | 11783 | -0.113 | -0.4971 | Yes |
| 95 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 11790 | -0.113 | -0.4892 | Yes |
| 96 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 11842 | -0.116 | -0.4844 | Yes |
| 97 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11904 | -0.119 | -0.4802 | Yes |
| 98 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12112 | -0.132 | -0.4861 | Yes |
| 99 | MTF2 | MTF2 Entrez, Source | metal response element binding transcription factor 2 | 12173 | -0.137 | -0.4805 | Yes |
| 100 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 12294 | -0.147 | -0.4787 | Yes |
| 101 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12381 | -0.156 | -0.4736 | Yes |
| 102 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 12395 | -0.157 | -0.4630 | Yes |
| 103 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 12403 | -0.158 | -0.4518 | Yes |
| 104 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 12574 | -0.181 | -0.4513 | Yes |
| 105 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 12594 | -0.184 | -0.4391 | Yes |
| 106 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 12600 | -0.184 | -0.4258 | Yes |
| 107 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 12697 | -0.204 | -0.4179 | Yes |
| 108 | NIPBL | NIPBL Entrez, Source | Nipped-B homolog (Drosophila) | 12794 | -0.223 | -0.4087 | Yes |
| 109 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12889 | -0.247 | -0.3975 | Yes |
| 110 | CEP170 | CEP170 Entrez, Source | centrosomal protein 170kDa | 12890 | -0.249 | -0.3790 | Yes |
| 111 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 12906 | -0.254 | -0.3613 | Yes |
| 112 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 12914 | -0.257 | -0.3428 | Yes |
| 113 | TRIO | TRIO Entrez, Source | triple functional domain (PTPRF interacting) | 12955 | -0.274 | -0.3255 | Yes |
| 114 | SPBC25 | SPBC25 Entrez, Source | spindle pole body component 25 homolog (S. cerevisiae) | 12974 | -0.280 | -0.3061 | Yes |
| 115 | ZNF292 | ZNF292 Entrez, Source | zinc finger protein 292 | 13006 | -0.293 | -0.2867 | Yes |
| 116 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 13035 | -0.310 | -0.2659 | Yes |
| 117 | RRAS2 | RRAS2 Entrez, Source | related RAS viral (r-ras) oncogene homolog 2 | 13055 | -0.322 | -0.2434 | Yes |
| 118 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13073 | -0.336 | -0.2199 | Yes |
| 119 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 13180 | -0.438 | -0.1954 | Yes |
| 120 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13260 | -0.571 | -0.1590 | Yes |
| 121 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13262 | -0.580 | -0.1161 | Yes |
| 122 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13308 | -0.800 | -0.0603 | Yes |
| 123 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13312 | -0.847 | 0.0023 | Yes |
