Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classsingle_gel_72h
GeneSetUVC_TTD_ALL_DN
Enrichment Score (ES)-0.4811139
Normalized Enrichment Score (NES)-1.8006598
Nominal p-value0.0
FDR q-value0.037226748
FWER p-Value0.969
Table: GSEA Results Summary



Fig 1: Enrichment plot: UVC_TTD_ALL_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CXCL12CXCL12
Entrez,  Source
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)500.5000.0252No
2DPYDDPYD
Entrez,  Source
dihydropyrimidine dehydrogenase3030.2650.0214No
3PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B3290.2570.0345No
4MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)4200.2240.0406No
5BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 26130.1840.0368No
6CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)7340.1690.0374No
7MGLLMGLL
Entrez,  Source
monoglyceride lipase7540.1670.0456No
8PRKCBP1PRKCBP1
Entrez,  Source
protein kinase C binding protein 19320.1500.0409No
9PTPN2PTPN2
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 211070.1370.0357No
10IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 114490.1160.0165No
11DLC1DLC1
Entrez,  Source
deleted in liver cancer 114830.1140.0206No
12GTF2F2GTF2F2
Entrez,  Source
general transcription factor IIF, polypeptide 2, 30kDa15690.1100.0205No
13MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)16090.1080.0239No
14KLF10KLF10
Entrez,  Source
Kruppel-like factor 1016930.1050.0237No
15FUT8FUT8
Entrez,  Source
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)17010.1050.0292No
16GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 118620.0990.0228No
17IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 319650.0950.0206No
18MBNL1MBNL1
Entrez,  Source
muscleblind-like (Drosophila)22910.0850.0009No
19PTPRMPTPRM
Entrez,  Source
protein tyrosine phosphatase, receptor type, M26390.075-0.0211No
20FGF5FGF5
Entrez,  Source
fibroblast growth factor 526560.075-0.0180No
21HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)27070.073-0.0175No
22FLNBFLNB
Entrez,  Source
filamin B, beta (actin binding protein 278)29300.068-0.0304No
23PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 1230860.065-0.0384No
24BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase31820.063-0.0420No
25FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES33740.059-0.0530No
26PEX14PEX14
Entrez,  Source
peroxisomal biogenesis factor 1435650.054-0.0643No
27RBM16RBM16
Entrez,  Source
RNA binding motif protein 1637350.051-0.0741No
28TMEM23TMEM23
Entrez,  Source
transmembrane protein 2337670.050-0.0736No
29ENC1ENC1
Entrez,  Source
ectodermal-neural cortex (with BTB-like domain)39170.048-0.0821No
30ZHX3ZHX3
Entrez,  Source
zinc fingers and homeoboxes 339780.047-0.0839No
31PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha39990.046-0.0828No
32FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)40300.046-0.0824No
33EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)40790.045-0.0834No
34EDG2EDG2
Entrez,  Source
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 242340.042-0.0926No
35HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like48220.032-0.1353No
36CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)49200.030-0.1409No
37ORC2LORC2L
Entrez,  Source
origin recognition complex, subunit 2-like (yeast)49480.030-0.1412No
38ATRXATRX
Entrez,  Source
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)50300.029-0.1457No
39GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)51190.027-0.1508No
40ATP2B1ATP2B1
Entrez,  Source
ATPase, Ca++ transporting, plasma membrane 154390.023-0.1736No
41MDN1MDN1
Entrez,  Source
MDN1, midasin homolog (yeast)54900.022-0.1762No
42MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 355020.022-0.1757No
43CEP350CEP350
Entrez,  Source
centrosomal protein 350kDa57350.018-0.1923No
44RBM39RBM39
Entrez,  Source
RNA binding motif protein 3957980.017-0.1960No
45MAPK6MAPK6
Entrez,  Source
mitogen-activated protein kinase 658560.016-0.1993No
46ARNT2ARNT2
Entrez,  Source
aryl-hydrocarbon receptor nuclear translocator 258710.016-0.1995No
47STK39STK39
Entrez,  Source
serine threonine kinase 39 (STE20/SPS1 homolog, yeast)59220.015-0.2024No
48SPOPSPOP
Entrez,  Source
speckle-type POZ protein60060.014-0.2078No
49RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)61020.013-0.2143No
50LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog61140.013-0.2144No
51AMPHAMPH
Entrez,  Source
amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)62910.010-0.2272No
52TSPAN5TSPAN5
Entrez,  Source
tetraspanin 564100.008-0.2357No
53DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 166730.004-0.2553No
54EIF4EEIF4E
Entrez,  Source
eukaryotic translation initiation factor 4E67030.004-0.2573No
55MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase68140.002-0.2655No
56TDRD3TDRD3
Entrez,  Source
tudor domain containing 368360.002-0.2670No
57PHLPPPHLPP
Entrez,  Source
PH domain and leucine rich repeat protein phosphatase69040.001-0.2720No
58MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 47050-0.001-0.2829No
59ZRF1ZRF1
Entrez,  Source
zuotin related factor 17203-0.003-0.2943No
60ZNF148ZNF148
Entrez,  Source
zinc finger protein 1487480-0.007-0.3148No
61SLC4A7SLC4A7
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 77486-0.007-0.3147No
62REV3LREV3L
Entrez,  Source
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)7625-0.009-0.3247No
63ITSN1ITSN1
Entrez,  Source
intersectin 1 (SH3 domain protein)7659-0.010-0.3266No
64TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 37754-0.011-0.3331No
65ACVR1ACVR1
Entrez,  Source
activin A receptor, type I7793-0.012-0.3352No
66SKAP2SKAP2
Entrez,  Source
src kinase associated phosphoprotein 27850-0.013-0.3387No
67MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)7962-0.014-0.3463No
68ACVR2AACVR2A
Entrez,  Source
activin A receptor, type IIA7984-0.015-0.3471No
69RGS7RGS7
Entrez,  Source
regulator of G-protein signalling 77991-0.015-0.3467No
70MYO1BMYO1B
Entrez,  Source
myosin IB8141-0.017-0.3570No
71DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A8340-0.020-0.3708No
72AFAPAFAP
Entrez,  Source
-8351-0.021-0.3704No
73PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase8393-0.021-0.3722No
74CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)8561-0.024-0.3835No
75OGTOGT
Entrez,  Source
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)8678-0.026-0.3908No
76NUP153NUP153
Entrez,  Source
nucleoporin 153kDa8693-0.026-0.3903No
77PPP1R12APPP1R12A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12A8798-0.028-0.3966No
78SIPA1L1SIPA1L1
Entrez,  Source
signal-induced proliferation-associated 1 like 18860-0.029-0.3995No
79PKN2PKN2
Entrez,  Source
protein kinase N28882-0.030-0.3994No
80ATF2ATF2
Entrez,  Source
activating transcription factor 29097-0.034-0.4137No
81MARCH7MARCH7
Entrez,  Source
membrane-associated ring finger (C3HC4) 79196-0.036-0.4190No
82FARS2FARS2
Entrez,  Source
phenylalanine-tRNA synthetase 2 (mitochondrial)9209-0.036-0.4179No
83PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa9229-0.036-0.4172No
84CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)9266-0.037-0.4178No
85SERPINB2SERPINB2
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 29372-0.039-0.4235No
86FUBP1FUBP1
Entrez,  Source
far upstream element (FUSE) binding protein 19417-0.040-0.4245No
87SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)9459-0.041-0.4252No
88ARIH1ARIH1
Entrez,  Source
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)9532-0.042-0.4282No
89NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 39534-0.042-0.4259No
90TCF12TCF12
Entrez,  Source
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)9690-0.045-0.4350No
91STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)9831-0.048-0.4428No
92WDR7WDR7
Entrez,  Source
WD repeat domain 79952-0.051-0.4489No
93NUP98NUP98
Entrez,  Source
nucleoporin 98kDa9998-0.052-0.4493No
94PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)10034-0.053-0.4489No
95CNOT4CNOT4
Entrez,  Source
CCR4-NOT transcription complex, subunit 410146-0.055-0.4541No
96SEPT9SEPT9
Entrez,  Source
septin 910261-0.058-0.4594No
97CUTL1CUTL1
Entrez,  Source
cut-like 1, CCAAT displacement protein (Drosophila)10279-0.058-0.4573No
98UBL3UBL3
Entrez,  Source
ubiquitin-like 310310-0.059-0.4562No
99SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)10513-0.064-0.4677No
100PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)10642-0.068-0.4735No
101NRG1NRG1
Entrez,  Source
neuregulin 110701-0.070-0.4739No
102PPP2R2APPP2R2A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform10720-0.070-0.4712No
103MTMR3MTMR3
Entrez,  Source
myotubularin related protein 310836-0.073-0.4756No
104CNOT2CNOT2
Entrez,  Source
CCR4-NOT transcription complex, subunit 210885-0.075-0.4749No
105ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein10891-0.075-0.4710No
106ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 1110901-0.075-0.4673No
107XRCC4XRCC4
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 411084-0.081-0.4764Yes
108PTPRKPTPRK
Entrez,  Source
protein tyrosine phosphatase, receptor type, K11105-0.082-0.4732Yes
109NFIBNFIB
Entrez,  Source
nuclear factor I/B11136-0.083-0.4706Yes
110BARD1BARD1
Entrez,  Source
BRCA1 associated RING domain 111154-0.084-0.4671Yes
111HAS2HAS2
Entrez,  Source
hyaluronan synthase 211211-0.086-0.4663Yes
112SYNJ2SYNJ2
Entrez,  Source
synaptojanin 211227-0.087-0.4624Yes
113STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 311294-0.090-0.4622Yes
114ATXN1ATXN1
Entrez,  Source
ataxin 111431-0.096-0.4669Yes
115GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11474-0.098-0.4644Yes
116MNAT1MNAT1
Entrez,  Source
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)11555-0.102-0.4646Yes
117PRIM2APRIM2A
Entrez,  Source
primase, polypeptide 2A, 58kDa11731-0.111-0.4715Yes
118CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 211749-0.111-0.4663Yes
119KIF2AKIF2A
Entrez,  Source
kinesin heavy chain member 2A11783-0.113-0.4623Yes
120ARHGEF7ARHGEF7
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 711790-0.113-0.4562Yes
121IL1RAPIL1RAP
Entrez,  Source
interleukin 1 receptor accessory protein11842-0.116-0.4533Yes
122PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 211904-0.119-0.4511Yes
123COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 212008-0.126-0.4516Yes
124TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 212112-0.132-0.4518Yes
125CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)12154-0.135-0.4471Yes
126MTF2MTF2
Entrez,  Source
metal response element binding transcription factor 212173-0.137-0.4405Yes
127CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 212294-0.147-0.4411Yes
128GPR176GPR176
Entrez,  Source
G protein-coupled receptor 17612322-0.150-0.4345Yes
129PCTK2PCTK2
Entrez,  Source
PCTAIRE protein kinase 212381-0.156-0.4298Yes
130CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase12395-0.157-0.4217Yes
131GNAQGNAQ
Entrez,  Source
guanine nucleotide binding protein (G protein), q polypeptide12403-0.158-0.4131Yes
132PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 112574-0.181-0.4155Yes
133CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b12594-0.184-0.4063Yes
134ABI1ABI1
Entrez,  Source
abl-interactor 112600-0.184-0.3960Yes
135VEGFCVEGFC
Entrez,  Source
vascular endothelial growth factor C12697-0.204-0.3915Yes
136NIPBLNIPBL
Entrez,  Source
Nipped-B homolog (Drosophila)12794-0.223-0.3858Yes
137TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)12889-0.247-0.3786Yes
138CEP170CEP170
Entrez,  Source
centrosomal protein 170kDa12890-0.249-0.3642Yes
139UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase12906-0.254-0.3506Yes
140CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 112914-0.257-0.3363Yes
141TRIOTRIO
Entrez,  Source
triple functional domain (PTPRF interacting)12955-0.274-0.3234Yes
142SPBC25SPBC25
Entrez,  Source
spindle pole body component 25 homolog (S. cerevisiae)12974-0.280-0.3086Yes
143ZNF292ZNF292
Entrez,  Source
zinc finger protein 29213006-0.293-0.2939Yes
144ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 213035-0.310-0.2781Yes
145RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 213055-0.322-0.2609Yes
146RUNX1RUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)13073-0.336-0.2427Yes
147CCND1CCND1
Entrez,  Source
cyclin D113085-0.343-0.2237Yes
148SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 113125-0.378-0.2048Yes
149SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113180-0.438-0.1835Yes
150CTGFCTGF
Entrez,  Source
connective tissue growth factor13260-0.571-0.1564Yes
151PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513261-0.575-0.1231Yes
152GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 113262-0.580-0.0895Yes
153F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)13308-0.800-0.0466Yes
154PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha13312-0.8470.0023Yes
Table: GSEA details [plain text format]



Fig 2: UVC_TTD_ALL_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: UVC_TTD_ALL_DN: Random ES distribution   
Gene set null distribution of ES for UVC_TTD_ALL_DN