Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$ARNT_02 |
| Enrichment Score (ES) | -0.49686462 |
| Normalized Enrichment Score (NES) | -1.735469 |
| Nominal p-value | 0.0015649452 |
| FDR q-value | 0.051302757 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 425 | 0.223 | -0.0144 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 445 | 0.217 | 0.0014 | No |
| 3 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 455 | 0.214 | 0.0177 | No |
| 4 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 542 | 0.194 | 0.0266 | No |
| 5 | GPM6B | GPM6B Entrez, Source | glycoprotein M6B | 593 | 0.187 | 0.0376 | No |
| 6 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 854 | 0.157 | 0.0304 | No |
| 7 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 1046 | 0.140 | 0.0272 | No |
| 8 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 1150 | 0.133 | 0.0299 | No |
| 9 | RAB24 | RAB24 Entrez, Source | RAB24, member RAS oncogene family | 1895 | 0.098 | -0.0185 | No |
| 10 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 2000 | 0.094 | -0.0189 | No |
| 11 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 2032 | 0.093 | -0.0139 | No |
| 12 | SLCO1C1 | SLCO1C1 Entrez, Source | solute carrier organic anion transporter family, member 1C1 | 2080 | 0.091 | -0.0102 | No |
| 13 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 2235 | 0.087 | -0.0150 | No |
| 14 | SEC23IP | SEC23IP Entrez, Source | SEC23 interacting protein | 2398 | 0.082 | -0.0207 | No |
| 15 | RRAGB | RRAGB Entrez, Source | Ras-related GTP binding B | 2465 | 0.081 | -0.0193 | No |
| 16 | PRSS15 | PRSS15 Entrez, Source | protease, serine, 15 | 2507 | 0.080 | -0.0161 | No |
| 17 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 2636 | 0.075 | -0.0198 | No |
| 18 | THUMPD2 | THUMPD2 Entrez, Source | THUMP domain containing 2 | 2676 | 0.074 | -0.0168 | No |
| 19 | GNAS | GNAS Entrez, Source | GNAS complex locus | 2815 | 0.071 | -0.0216 | No |
| 20 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3058 | 0.065 | -0.0347 | No |
| 21 | FXYD6 | FXYD6 Entrez, Source | FXYD domain containing ion transport regulator 6 | 3201 | 0.062 | -0.0405 | No |
| 22 | CANX | CANX Entrez, Source | calnexin | 3355 | 0.059 | -0.0474 | No |
| 23 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 3412 | 0.058 | -0.0471 | No |
| 24 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 3601 | 0.054 | -0.0570 | No |
| 25 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 3696 | 0.052 | -0.0600 | No |
| 26 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 3836 | 0.049 | -0.0666 | No |
| 27 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 4018 | 0.046 | -0.0766 | No |
| 28 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 5021 | 0.029 | -0.1501 | No |
| 29 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 5022 | 0.029 | -0.1478 | No |
| 30 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 5090 | 0.028 | -0.1507 | No |
| 31 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 5208 | 0.026 | -0.1574 | No |
| 32 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 5283 | 0.025 | -0.1611 | No |
| 33 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 5354 | 0.024 | -0.1645 | No |
| 34 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 5562 | 0.021 | -0.1784 | No |
| 35 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5676 | 0.019 | -0.1855 | No |
| 36 | ATP6V1H | ATP6V1H Entrez, Source | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 5858 | 0.016 | -0.1978 | No |
| 37 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 6037 | 0.014 | -0.2102 | No |
| 38 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 6063 | 0.013 | -0.2110 | No |
| 39 | HOXA1 | HOXA1 Entrez, Source | homeobox A1 | 6083 | 0.013 | -0.2114 | No |
| 40 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 6157 | 0.012 | -0.2160 | No |
| 41 | SLC38A5 | SLC38A5 Entrez, Source | solute carrier family 38, member 5 | 6165 | 0.012 | -0.2156 | No |
| 42 | GGN | GGN Entrez, Source | gametogenetin | 6394 | 0.008 | -0.2322 | No |
| 43 | NCL | NCL Entrez, Source | nucleolin | 6959 | 0.000 | -0.2748 | No |
| 44 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 7135 | -0.002 | -0.2878 | No |
| 45 | LTBR | LTBR Entrez, Source | lymphotoxin beta receptor (TNFR superfamily, member 3) | 7154 | -0.002 | -0.2890 | No |
| 46 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 7196 | -0.003 | -0.2919 | No |
| 47 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 7199 | -0.003 | -0.2918 | No |
| 48 | CLTC | CLTC Entrez, Source | clathrin, heavy chain (Hc) | 7722 | -0.011 | -0.3304 | No |
| 49 | CUL5 | CUL5 Entrez, Source | cullin 5 | 7748 | -0.011 | -0.3314 | No |
| 50 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 7831 | -0.013 | -0.3366 | No |
| 51 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 7948 | -0.014 | -0.3442 | No |
| 52 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 8085 | -0.016 | -0.3532 | No |
| 53 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 8205 | -0.018 | -0.3608 | No |
| 54 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 8304 | -0.020 | -0.3666 | No |
| 55 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 8431 | -0.022 | -0.3744 | No |
| 56 | AVPI1 | AVPI1 Entrez, Source | arginine vasopressin-induced 1 | 8442 | -0.022 | -0.3734 | No |
| 57 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 8550 | -0.024 | -0.3796 | No |
| 58 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 8687 | -0.026 | -0.3878 | No |
| 59 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 8973 | -0.032 | -0.4068 | No |
| 60 | TUBA4 | TUBA4 Entrez, Source | tubulin, alpha 4 | 8987 | -0.032 | -0.4053 | No |
| 61 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 9118 | -0.034 | -0.4124 | No |
| 62 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 9179 | -0.035 | -0.4141 | No |
| 63 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 9276 | -0.037 | -0.4184 | No |
| 64 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 9286 | -0.038 | -0.4161 | No |
| 65 | HRH3 | HRH3 Entrez, Source | histamine receptor H3 | 9350 | -0.039 | -0.4178 | No |
| 66 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 9368 | -0.039 | -0.4160 | No |
| 67 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 9683 | -0.045 | -0.4361 | No |
| 68 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 9688 | -0.045 | -0.4328 | No |
| 69 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 9765 | -0.047 | -0.4348 | No |
| 70 | BAX | BAX Entrez, Source | BCL2-associated X protein | 9773 | -0.047 | -0.4316 | No |
| 71 | ZIC1 | ZIC1 Entrez, Source | Zic family member 1 (odd-paired homolog, Drosophila) | 9968 | -0.051 | -0.4422 | No |
| 72 | NEUROD2 | NEUROD2 Entrez, Source | neurogenic differentiation 2 | 10039 | -0.053 | -0.4433 | No |
| 73 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 10118 | -0.055 | -0.4448 | No |
| 74 | RNF44 | RNF44 Entrez, Source | ring finger protein 44 | 10288 | -0.059 | -0.4529 | No |
| 75 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 10318 | -0.060 | -0.4504 | No |
| 76 | PDCD6IP | PDCD6IP Entrez, Source | programmed cell death 6 interacting protein | 10508 | -0.064 | -0.4596 | No |
| 77 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 10722 | -0.070 | -0.4701 | No |
| 78 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11071 | -0.081 | -0.4900 | No |
| 79 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 11163 | -0.084 | -0.4902 | Yes |
| 80 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 11219 | -0.087 | -0.4875 | Yes |
| 81 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 11249 | -0.088 | -0.4827 | Yes |
| 82 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 11252 | -0.088 | -0.4759 | Yes |
| 83 | SNX16 | SNX16 Entrez, Source | sorting nexin 16 | 11420 | -0.096 | -0.4809 | Yes |
| 84 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 11499 | -0.099 | -0.4789 | Yes |
| 85 | SPG21 | SPG21 Entrez, Source | spastic paraplegia 21, maspardin (autosomal recessive, Mast syndrome) | 11507 | -0.100 | -0.4715 | Yes |
| 86 | TRIM3 | TRIM3 Entrez, Source | tripartite motif-containing 3 | 11524 | -0.100 | -0.4648 | Yes |
| 87 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11527 | -0.101 | -0.4570 | Yes |
| 88 | CAMK2D | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | 11618 | -0.105 | -0.4554 | Yes |
| 89 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 12016 | -0.126 | -0.4754 | Yes |
| 90 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12086 | -0.130 | -0.4703 | Yes |
| 91 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 12127 | -0.133 | -0.4627 | Yes |
| 92 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 12212 | -0.140 | -0.4580 | Yes |
| 93 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 12448 | -0.164 | -0.4627 | Yes |
| 94 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 12459 | -0.165 | -0.4504 | Yes |
| 95 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 12472 | -0.167 | -0.4381 | Yes |
| 96 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 12528 | -0.175 | -0.4284 | Yes |
| 97 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 12602 | -0.184 | -0.4192 | Yes |
| 98 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 12628 | -0.189 | -0.4061 | Yes |
| 99 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 12640 | -0.193 | -0.3917 | Yes |
| 100 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12735 | -0.210 | -0.3821 | Yes |
| 101 | SNN | SNN Entrez, Source | stannin | 12747 | -0.213 | -0.3660 | Yes |
| 102 | STX6 | STX6 Entrez, Source | syntaxin 6 | 12878 | -0.244 | -0.3565 | Yes |
| 103 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 12998 | -0.290 | -0.3425 | Yes |
| 104 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13183 | -0.443 | -0.3212 | Yes |
| 105 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13187 | -0.451 | -0.2857 | Yes |
| 106 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13218 | -0.493 | -0.2489 | Yes |
| 107 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13242 | -0.532 | -0.2085 | Yes |
| 108 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 13291 | -0.715 | -0.1554 | Yes |
| 109 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | -0.0963 | Yes |
| 110 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 13335 | -1.251 | 0.0005 | Yes |
