Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$CP2_02 |
| Enrichment Score (ES) | -0.5456467 |
| Normalized Enrichment Score (NES) | -1.8817607 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.023638124 |
| FWER p-Value | 0.678 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 472 | 0.210 | -0.0149 | No |
| 2 | CNTN6 | CNTN6 Entrez, Source | contactin 6 | 494 | 0.204 | 0.0037 | No |
| 3 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 1487 | 0.114 | -0.0599 | No |
| 4 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1526 | 0.112 | -0.0517 | No |
| 5 | FEV | FEV Entrez, Source | FEV (ETS oncogene family) | 1641 | 0.107 | -0.0497 | No |
| 6 | RGS8 | RGS8 Entrez, Source | regulator of G-protein signalling 8 | 1979 | 0.094 | -0.0657 | No |
| 7 | ARHGAP5 | ARHGAP5 Entrez, Source | Rho GTPase activating protein 5 | 2217 | 0.088 | -0.0750 | No |
| 8 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 2854 | 0.070 | -0.1160 | No |
| 9 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 2983 | 0.067 | -0.1191 | No |
| 10 | GPC3 | GPC3 Entrez, Source | glypican 3 | 3083 | 0.065 | -0.1201 | No |
| 11 | NTRK3 | NTRK3 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 3 | 3188 | 0.063 | -0.1218 | No |
| 12 | SCAMP5 | SCAMP5 Entrez, Source | secretory carrier membrane protein 5 | 3259 | 0.061 | -0.1210 | No |
| 13 | MAPRE3 | MAPRE3 Entrez, Source | microtubule-associated protein, RP/EB family, member 3 | 3542 | 0.055 | -0.1369 | No |
| 14 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 3601 | 0.054 | -0.1359 | No |
| 15 | GRB7 | GRB7 Entrez, Source | growth factor receptor-bound protein 7 | 3678 | 0.052 | -0.1365 | No |
| 16 | CS | CS Entrez, Source | citrate synthase | 4175 | 0.043 | -0.1696 | No |
| 17 | PRKCH | PRKCH Entrez, Source | protein kinase C, eta | 4516 | 0.038 | -0.1916 | No |
| 18 | CITED1 | CITED1 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 4671 | 0.035 | -0.1997 | No |
| 19 | DCX | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 4710 | 0.034 | -0.1992 | No |
| 20 | PTHLH | PTHLH Entrez, Source | parathyroid hormone-like hormone | 5115 | 0.027 | -0.2270 | No |
| 21 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 5181 | 0.027 | -0.2293 | No |
| 22 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 5235 | 0.026 | -0.2307 | No |
| 23 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 5277 | 0.025 | -0.2314 | No |
| 24 | AQP6 | AQP6 Entrez, Source | aquaporin 6, kidney specific | 5330 | 0.024 | -0.2329 | No |
| 25 | XPNPEP1 | XPNPEP1 Entrez, Source | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 5450 | 0.022 | -0.2396 | No |
| 26 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 5487 | 0.022 | -0.2402 | No |
| 27 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 5562 | 0.021 | -0.2437 | No |
| 28 | EFNA3 | EFNA3 Entrez, Source | ephrin-A3 | 5988 | 0.014 | -0.2744 | No |
| 29 | RPL41 | RPL41 Entrez, Source | ribosomal protein L41 | 6066 | 0.013 | -0.2789 | No |
| 30 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 6114 | 0.013 | -0.2812 | No |
| 31 | KCNC2 | KCNC2 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 2 | 6267 | 0.010 | -0.2916 | No |
| 32 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 6400 | 0.008 | -0.3008 | No |
| 33 | RHBDF1 | RHBDF1 Entrez, Source | rhomboid 5 homolog 1 (Drosophila) | 7142 | -0.002 | -0.3565 | No |
| 34 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 7348 | -0.005 | -0.3715 | No |
| 35 | KIF5A | KIF5A Entrez, Source | kinesin family member 5A | 7406 | -0.006 | -0.3752 | No |
| 36 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 7459 | -0.007 | -0.3785 | No |
| 37 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 7495 | -0.007 | -0.3804 | No |
| 38 | EPN3 | EPN3 Entrez, Source | epsin 3 | 7663 | -0.010 | -0.3920 | No |
| 39 | PRKACA | PRKACA Entrez, Source | protein kinase, cAMP-dependent, catalytic, alpha | 7732 | -0.011 | -0.3960 | No |
| 40 | LHX2 | LHX2 Entrez, Source | LIM homeobox 2 | 7755 | -0.011 | -0.3966 | No |
| 41 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 7831 | -0.013 | -0.4010 | No |
| 42 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 7871 | -0.013 | -0.4026 | No |
| 43 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 7987 | -0.015 | -0.4099 | No |
| 44 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 8175 | -0.018 | -0.4222 | No |
| 45 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 8249 | -0.019 | -0.4259 | No |
| 46 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 8491 | -0.023 | -0.4418 | No |
| 47 | RASSF1 | RASSF1 Entrez, Source | Ras association (RalGDS/AF-6) domain family 1 | 8495 | -0.023 | -0.4397 | No |
| 48 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 8687 | -0.026 | -0.4516 | No |
| 49 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9430 | -0.040 | -0.5036 | No |
| 50 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 9431 | -0.040 | -0.4996 | No |
| 51 | CAMK2G | CAMK2G Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma | 9525 | -0.042 | -0.5025 | No |
| 52 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 9663 | -0.045 | -0.5084 | No |
| 53 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9743 | -0.047 | -0.5097 | No |
| 54 | KCNE3 | KCNE3 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 3 | 9875 | -0.049 | -0.5147 | No |
| 55 | GNB3 | GNB3 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 9976 | -0.052 | -0.5171 | No |
| 56 | BTBD14B | BTBD14B Entrez, Source | BTB (POZ) domain containing 14B | 10049 | -0.053 | -0.5173 | No |
| 57 | DHH | DHH Entrez, Source | desert hedgehog homolog (Drosophila) | 10100 | -0.054 | -0.5157 | No |
| 58 | C1QTNF5 | C1QTNF5 Entrez, Source | C1q and tumor necrosis factor related protein 5 | 10143 | -0.055 | -0.5134 | No |
| 59 | FGF9 | FGF9 Entrez, Source | fibroblast growth factor 9 (glia-activating factor) | 10145 | -0.055 | -0.5080 | No |
| 60 | CAPN6 | CAPN6 Entrez, Source | calpain 6 | 10215 | -0.057 | -0.5075 | No |
| 61 | RAB10 | RAB10 Entrez, Source | RAB10, member RAS oncogene family | 10219 | -0.057 | -0.5021 | No |
| 62 | CLDN4 | CLDN4 Entrez, Source | claudin 4 | 10487 | -0.064 | -0.5159 | No |
| 63 | ADRA1A | ADRA1A Entrez, Source | adrenergic, alpha-1A-, receptor | 10505 | -0.064 | -0.5108 | No |
| 64 | ADNP | ADNP Entrez, Source | activity-dependent neuroprotector | 10585 | -0.066 | -0.5102 | No |
| 65 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 10717 | -0.070 | -0.5131 | No |
| 66 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 10984 | -0.078 | -0.5255 | No |
| 67 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 11252 | -0.088 | -0.5369 | Yes |
| 68 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 11367 | -0.093 | -0.5363 | Yes |
| 69 | HPCAL1 | HPCAL1 Entrez, Source | hippocalcin-like 1 | 11438 | -0.097 | -0.5320 | Yes |
| 70 | FLOT2 | FLOT2 Entrez, Source | flotillin 2 | 11454 | -0.098 | -0.5234 | Yes |
| 71 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11474 | -0.098 | -0.5151 | Yes |
| 72 | RYR1 | RYR1 Entrez, Source | ryanodine receptor 1 (skeletal) | 11608 | -0.105 | -0.5148 | Yes |
| 73 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 11663 | -0.108 | -0.5082 | Yes |
| 74 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 11745 | -0.111 | -0.5033 | Yes |
| 75 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 11876 | -0.118 | -0.5014 | Yes |
| 76 | NNAT | NNAT Entrez, Source | neuronatin | 12027 | -0.127 | -0.5002 | Yes |
| 77 | TLN1 | TLN1 Entrez, Source | talin 1 | 12039 | -0.127 | -0.4884 | Yes |
| 78 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 12198 | -0.139 | -0.4866 | Yes |
| 79 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 12212 | -0.140 | -0.4736 | Yes |
| 80 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 12239 | -0.143 | -0.4614 | Yes |
| 81 | NISCH | NISCH Entrez, Source | nischarin | 12301 | -0.148 | -0.4513 | Yes |
| 82 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 12403 | -0.158 | -0.4433 | Yes |
| 83 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12441 | -0.162 | -0.4300 | Yes |
| 84 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 12528 | -0.175 | -0.4191 | Yes |
| 85 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 12582 | -0.181 | -0.4051 | Yes |
| 86 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12690 | -0.203 | -0.3931 | Yes |
| 87 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 12784 | -0.220 | -0.3783 | Yes |
| 88 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12826 | -0.231 | -0.3585 | Yes |
| 89 | GPRC5C | GPRC5C Entrez, Source | G protein-coupled receptor, family C, group 5, member C | 12872 | -0.243 | -0.3379 | Yes |
| 90 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 12900 | -0.253 | -0.3149 | Yes |
| 91 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13183 | -0.443 | -0.2922 | Yes |
| 92 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 13214 | -0.489 | -0.2460 | Yes |
| 93 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13242 | -0.532 | -0.1954 | Yes |
| 94 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13271 | -0.644 | -0.1337 | Yes |
| 95 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13279 | -0.655 | -0.0693 | Yes |
| 96 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13300 | -0.747 | 0.0032 | Yes |
