Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$E2F1_Q4_01 |
| Enrichment Score (ES) | -0.49112245 |
| Normalized Enrichment Score (NES) | -1.7056593 |
| Nominal p-value | 0.0016233766 |
| FDR q-value | 0.061600134 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 37 | 0.535 | 0.0523 | No |
| 2 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 436 | 0.220 | 0.0449 | No |
| 3 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | 0.0442 | No |
| 4 | HTF9C | HTF9C Entrez, Source | - | 1256 | 0.127 | 0.0143 | No |
| 5 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1609 | 0.108 | -0.0011 | No |
| 6 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1646 | 0.107 | 0.0072 | No |
| 7 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2243 | 0.086 | -0.0289 | No |
| 8 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 2263 | 0.086 | -0.0215 | No |
| 9 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 2318 | 0.085 | -0.0168 | No |
| 10 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2527 | 0.079 | -0.0244 | No |
| 11 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 2669 | 0.074 | -0.0274 | No |
| 12 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 2719 | 0.073 | -0.0235 | No |
| 13 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 2896 | 0.069 | -0.0297 | No |
| 14 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 2936 | 0.068 | -0.0256 | No |
| 15 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 3098 | 0.064 | -0.0312 | No |
| 16 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3161 | 0.063 | -0.0293 | No |
| 17 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 3680 | 0.052 | -0.0630 | No |
| 18 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 3701 | 0.052 | -0.0592 | No |
| 19 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 3750 | 0.051 | -0.0576 | No |
| 20 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 3790 | 0.050 | -0.0554 | No |
| 21 | CHGB | CHGB Entrez, Source | chromogranin B (secretogranin 1) | 3840 | 0.049 | -0.0540 | No |
| 22 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 3898 | 0.048 | -0.0533 | No |
| 23 | XTP3TPA | XTP3TPA Entrez, Source | - | 4144 | 0.044 | -0.0673 | No |
| 24 | PELO | PELO Entrez, Source | pelota homolog (Drosophila) | 4563 | 0.037 | -0.0950 | No |
| 25 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 5030 | 0.029 | -0.1273 | No |
| 26 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5066 | 0.028 | -0.1270 | No |
| 27 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 5107 | 0.028 | -0.1272 | No |
| 28 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 5188 | 0.026 | -0.1305 | No |
| 29 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 5518 | 0.021 | -0.1531 | No |
| 30 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 5597 | 0.020 | -0.1569 | No |
| 31 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5968 | 0.015 | -0.1833 | No |
| 32 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5972 | 0.015 | -0.1821 | No |
| 33 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 6036 | 0.014 | -0.1854 | No |
| 34 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 6063 | 0.013 | -0.1860 | No |
| 35 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 6208 | 0.011 | -0.1957 | No |
| 36 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 6801 | 0.003 | -0.2401 | No |
| 37 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6821 | 0.002 | -0.2413 | No |
| 38 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 6857 | 0.002 | -0.2437 | No |
| 39 | NCL | NCL Entrez, Source | nucleolin | 6959 | 0.000 | -0.2513 | No |
| 40 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | -0.2518 | No |
| 41 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 7147 | -0.002 | -0.2651 | No |
| 42 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 7175 | -0.003 | -0.2669 | No |
| 43 | NUP155 | NUP155 Entrez, Source | nucleoporin 155kDa | 7188 | -0.003 | -0.2675 | No |
| 44 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7214 | -0.003 | -0.2690 | No |
| 45 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 7575 | -0.009 | -0.2953 | No |
| 46 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 7648 | -0.010 | -0.2997 | No |
| 47 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 8004 | -0.015 | -0.3250 | No |
| 48 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 8170 | -0.017 | -0.3356 | No |
| 49 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 8231 | -0.019 | -0.3382 | No |
| 50 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8480 | -0.023 | -0.3546 | No |
| 51 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8589 | -0.025 | -0.3602 | No |
| 52 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 8693 | -0.026 | -0.3653 | No |
| 53 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 8771 | -0.028 | -0.3683 | No |
| 54 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 8822 | -0.029 | -0.3691 | No |
| 55 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8874 | -0.029 | -0.3699 | No |
| 56 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8996 | -0.032 | -0.3757 | No |
| 57 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 9224 | -0.036 | -0.3891 | No |
| 58 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 9235 | -0.036 | -0.3861 | No |
| 59 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 9405 | -0.040 | -0.3948 | No |
| 60 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9644 | -0.044 | -0.4082 | No |
| 61 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9743 | -0.047 | -0.4108 | No |
| 62 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9846 | -0.049 | -0.4135 | No |
| 63 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9930 | -0.051 | -0.4145 | No |
| 64 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 10624 | -0.068 | -0.4598 | No |
| 65 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 10772 | -0.072 | -0.4635 | No |
| 66 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11071 | -0.081 | -0.4777 | No |
| 67 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 11163 | -0.084 | -0.4759 | No |
| 68 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 11325 | -0.092 | -0.4786 | No |
| 69 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11390 | -0.094 | -0.4737 | No |
| 70 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 11622 | -0.106 | -0.4802 | Yes |
| 71 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11643 | -0.106 | -0.4708 | Yes |
| 72 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11689 | -0.109 | -0.4630 | Yes |
| 73 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 11712 | -0.110 | -0.4534 | Yes |
| 74 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 11893 | -0.118 | -0.4548 | Yes |
| 75 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 12088 | -0.130 | -0.4560 | Yes |
| 76 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12107 | -0.132 | -0.4438 | Yes |
| 77 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 12376 | -0.156 | -0.4479 | Yes |
| 78 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12413 | -0.160 | -0.4342 | Yes |
| 79 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 12429 | -0.161 | -0.4187 | Yes |
| 80 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12466 | -0.166 | -0.4044 | Yes |
| 81 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12601 | -0.184 | -0.3955 | Yes |
| 82 | DHX40 | DHX40 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 12647 | -0.194 | -0.3789 | Yes |
| 83 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 12673 | -0.198 | -0.3603 | Yes |
| 84 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12889 | -0.247 | -0.3511 | Yes |
| 85 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12929 | -0.262 | -0.3271 | Yes |
| 86 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12957 | -0.275 | -0.3008 | Yes |
| 87 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13048 | -0.319 | -0.2747 | Yes |
| 88 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13127 | -0.379 | -0.2416 | Yes |
| 89 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.1988 | Yes |
| 90 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.1402 | Yes |
| 91 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13280 | -0.659 | -0.0732 | Yes |
| 92 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | 0.0030 | Yes |
