Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$E2F_Q3_01 |
| Enrichment Score (ES) | -0.5053733 |
| Normalized Enrichment Score (NES) | -1.7301142 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.05261472 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 37 | 0.535 | 0.0507 | No |
| 2 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 436 | 0.220 | 0.0427 | No |
| 3 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | 0.0414 | No |
| 4 | HTF9C | HTF9C Entrez, Source | - | 1256 | 0.127 | 0.0112 | No |
| 5 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1609 | 0.108 | -0.0046 | No |
| 6 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1646 | 0.107 | 0.0034 | No |
| 7 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2243 | 0.086 | -0.0329 | No |
| 8 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 2263 | 0.086 | -0.0257 | No |
| 9 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 2318 | 0.085 | -0.0213 | No |
| 10 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2527 | 0.079 | -0.0291 | No |
| 11 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 2669 | 0.074 | -0.0323 | No |
| 12 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 2719 | 0.073 | -0.0287 | No |
| 13 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 2896 | 0.069 | -0.0351 | No |
| 14 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 2936 | 0.068 | -0.0312 | No |
| 15 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 3098 | 0.064 | -0.0369 | No |
| 16 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3161 | 0.063 | -0.0353 | No |
| 17 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 3680 | 0.052 | -0.0692 | No |
| 18 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 3701 | 0.052 | -0.0655 | No |
| 19 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 3750 | 0.051 | -0.0640 | No |
| 20 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 3790 | 0.050 | -0.0620 | No |
| 21 | CHGB | CHGB Entrez, Source | chromogranin B (secretogranin 1) | 3840 | 0.049 | -0.0607 | No |
| 22 | XTP3TPA | XTP3TPA Entrez, Source | - | 4144 | 0.044 | -0.0792 | No |
| 23 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4335 | 0.040 | -0.0895 | No |
| 24 | PELO | PELO Entrez, Source | pelota homolog (Drosophila) | 4563 | 0.037 | -0.1029 | No |
| 25 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5066 | 0.028 | -0.1380 | No |
| 26 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 5107 | 0.028 | -0.1383 | No |
| 27 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 5188 | 0.026 | -0.1417 | No |
| 28 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 5518 | 0.021 | -0.1643 | No |
| 29 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 5597 | 0.020 | -0.1682 | No |
| 30 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5968 | 0.015 | -0.1946 | No |
| 31 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5972 | 0.015 | -0.1934 | No |
| 32 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 6063 | 0.013 | -0.1989 | No |
| 33 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 6208 | 0.011 | -0.2086 | No |
| 34 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 6476 | 0.007 | -0.2281 | No |
| 35 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 6801 | 0.003 | -0.2523 | No |
| 36 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6821 | 0.002 | -0.2535 | No |
| 37 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 6857 | 0.002 | -0.2559 | No |
| 38 | NCL | NCL Entrez, Source | nucleolin | 6959 | 0.000 | -0.2635 | No |
| 39 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | -0.2640 | No |
| 40 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 7147 | -0.002 | -0.2773 | No |
| 41 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 7175 | -0.003 | -0.2791 | No |
| 42 | NUP155 | NUP155 Entrez, Source | nucleoporin 155kDa | 7188 | -0.003 | -0.2797 | No |
| 43 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7214 | -0.003 | -0.2812 | No |
| 44 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 7575 | -0.009 | -0.3076 | No |
| 45 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 7648 | -0.010 | -0.3120 | No |
| 46 | PELP1 | PELP1 Entrez, Source | proline, glutamic acid and leucine rich protein 1 | 7677 | -0.010 | -0.3131 | No |
| 47 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 8004 | -0.015 | -0.3362 | No |
| 48 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 8170 | -0.017 | -0.3469 | No |
| 49 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 8231 | -0.019 | -0.3496 | No |
| 50 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8480 | -0.023 | -0.3660 | No |
| 51 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8589 | -0.025 | -0.3717 | No |
| 52 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 8693 | -0.026 | -0.3769 | No |
| 53 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 8771 | -0.028 | -0.3799 | No |
| 54 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 8822 | -0.029 | -0.3808 | No |
| 55 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8874 | -0.029 | -0.3817 | No |
| 56 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8996 | -0.032 | -0.3877 | No |
| 57 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 9224 | -0.036 | -0.4012 | No |
| 58 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 9235 | -0.036 | -0.3983 | No |
| 59 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 9405 | -0.040 | -0.4070 | No |
| 60 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9644 | -0.044 | -0.4206 | No |
| 61 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9743 | -0.047 | -0.4233 | No |
| 62 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9846 | -0.049 | -0.4261 | No |
| 63 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9930 | -0.051 | -0.4273 | No |
| 64 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 10624 | -0.068 | -0.4728 | No |
| 65 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 10772 | -0.072 | -0.4768 | No |
| 66 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11071 | -0.081 | -0.4912 | No |
| 67 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 11163 | -0.084 | -0.4896 | No |
| 68 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 11325 | -0.092 | -0.4926 | No |
| 69 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11390 | -0.094 | -0.4879 | No |
| 70 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 11622 | -0.106 | -0.4948 | Yes |
| 71 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11643 | -0.106 | -0.4857 | Yes |
| 72 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11689 | -0.109 | -0.4782 | Yes |
| 73 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 11712 | -0.110 | -0.4689 | Yes |
| 74 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 11893 | -0.118 | -0.4707 | Yes |
| 75 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 12088 | -0.130 | -0.4722 | Yes |
| 76 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12107 | -0.132 | -0.4604 | Yes |
| 77 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 12376 | -0.156 | -0.4650 | Yes |
| 78 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12413 | -0.160 | -0.4518 | Yes |
| 79 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12466 | -0.166 | -0.4392 | Yes |
| 80 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12601 | -0.184 | -0.4308 | Yes |
| 81 | DHX40 | DHX40 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 12647 | -0.194 | -0.4148 | Yes |
| 82 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 12673 | -0.198 | -0.3968 | Yes |
| 83 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12889 | -0.247 | -0.3883 | Yes |
| 84 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12929 | -0.262 | -0.3650 | Yes |
| 85 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12957 | -0.275 | -0.3395 | Yes |
| 86 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13048 | -0.319 | -0.3144 | Yes |
| 87 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13127 | -0.379 | -0.2824 | Yes |
| 88 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.2410 | Yes |
| 89 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13211 | -0.481 | -0.1933 | Yes |
| 90 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.1360 | Yes |
| 91 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13280 | -0.659 | -0.0710 | Yes |
| 92 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | 0.0030 | Yes |
