Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$E2F_Q4 |
| Enrichment Score (ES) | -0.521668 |
| Normalized Enrichment Score (NES) | -1.790795 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.038889512 |
| FWER p-Value | 0.984 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 445 | 0.217 | -0.0117 | No |
| 2 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | -0.0122 | No |
| 3 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 854 | 0.157 | -0.0089 | No |
| 4 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 979 | 0.147 | -0.0035 | No |
| 5 | HTF9C | HTF9C Entrez, Source | - | 1256 | 0.127 | -0.0115 | No |
| 6 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 1277 | 0.125 | -0.0004 | No |
| 7 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1646 | 0.107 | -0.0174 | No |
| 8 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 1741 | 0.104 | -0.0141 | No |
| 9 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 2205 | 0.088 | -0.0402 | No |
| 10 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 2238 | 0.087 | -0.0338 | No |
| 11 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2243 | 0.086 | -0.0254 | No |
| 12 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 2453 | 0.081 | -0.0330 | No |
| 13 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2527 | 0.079 | -0.0306 | No |
| 14 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 2719 | 0.073 | -0.0377 | No |
| 15 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 2936 | 0.068 | -0.0471 | No |
| 16 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 3069 | 0.065 | -0.0505 | No |
| 17 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 3098 | 0.064 | -0.0462 | No |
| 18 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 3136 | 0.064 | -0.0425 | No |
| 19 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3161 | 0.063 | -0.0380 | No |
| 20 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 3680 | 0.052 | -0.0718 | No |
| 21 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 3701 | 0.052 | -0.0681 | No |
| 22 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 3728 | 0.051 | -0.0649 | No |
| 23 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 3750 | 0.051 | -0.0614 | No |
| 24 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 3763 | 0.051 | -0.0572 | No |
| 25 | XTP3TPA | XTP3TPA Entrez, Source | - | 4144 | 0.044 | -0.0814 | No |
| 26 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 4359 | 0.040 | -0.0936 | No |
| 27 | CORT | CORT Entrez, Source | cortistatin | 4395 | 0.040 | -0.0922 | No |
| 28 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5066 | 0.028 | -0.1399 | No |
| 29 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 5113 | 0.027 | -0.1406 | No |
| 30 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 5188 | 0.026 | -0.1436 | No |
| 31 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 5597 | 0.020 | -0.1723 | No |
| 32 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5968 | 0.015 | -0.1987 | No |
| 33 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5972 | 0.015 | -0.1975 | No |
| 34 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 6063 | 0.013 | -0.2030 | No |
| 35 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 6208 | 0.011 | -0.2127 | No |
| 36 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 6515 | 0.006 | -0.2352 | No |
| 37 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 6611 | 0.005 | -0.2418 | No |
| 38 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 6717 | 0.004 | -0.2494 | No |
| 39 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6821 | 0.002 | -0.2569 | No |
| 40 | NCL | NCL Entrez, Source | nucleolin | 6959 | 0.000 | -0.2672 | No |
| 41 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | -0.2677 | No |
| 42 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 7147 | -0.002 | -0.2810 | No |
| 43 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7214 | -0.003 | -0.2856 | No |
| 44 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 7338 | -0.005 | -0.2944 | No |
| 45 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 7648 | -0.010 | -0.3168 | No |
| 46 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 7860 | -0.013 | -0.3314 | No |
| 47 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 8004 | -0.015 | -0.3406 | No |
| 48 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 8206 | -0.018 | -0.3540 | No |
| 49 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 8221 | -0.018 | -0.3532 | No |
| 50 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8589 | -0.025 | -0.3784 | No |
| 51 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 8693 | -0.026 | -0.3835 | No |
| 52 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 8800 | -0.028 | -0.3887 | No |
| 53 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 8822 | -0.029 | -0.3874 | No |
| 54 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8874 | -0.029 | -0.3883 | No |
| 55 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8996 | -0.032 | -0.3942 | No |
| 56 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 9166 | -0.035 | -0.4034 | No |
| 57 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 9405 | -0.040 | -0.4174 | No |
| 58 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9430 | -0.040 | -0.4151 | No |
| 59 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 9770 | -0.047 | -0.4359 | No |
| 60 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9846 | -0.049 | -0.4367 | No |
| 61 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 9909 | -0.050 | -0.4363 | No |
| 62 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9930 | -0.051 | -0.4327 | No |
| 63 | FANCD2 | FANCD2 Entrez, Source | Fanconi anemia, complementation group D2 | 10129 | -0.055 | -0.4421 | No |
| 64 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 10199 | -0.057 | -0.4416 | No |
| 65 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 10233 | -0.058 | -0.4383 | No |
| 66 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 10624 | -0.068 | -0.4609 | No |
| 67 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 10772 | -0.072 | -0.4648 | No |
| 68 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11071 | -0.081 | -0.4791 | No |
| 69 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11390 | -0.094 | -0.4936 | No |
| 70 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11643 | -0.106 | -0.5020 | No |
| 71 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11689 | -0.109 | -0.4944 | No |
| 72 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 11893 | -0.118 | -0.4978 | No |
| 73 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 11981 | -0.124 | -0.4919 | No |
| 74 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 12376 | -0.156 | -0.5060 | Yes |
| 75 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12413 | -0.160 | -0.4926 | Yes |
| 76 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12432 | -0.162 | -0.4777 | Yes |
| 77 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12466 | -0.166 | -0.4635 | Yes |
| 78 | TMPO | TMPO Entrez, Source | thymopoietin | 12590 | -0.183 | -0.4543 | Yes |
| 79 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 12673 | -0.198 | -0.4406 | Yes |
| 80 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12929 | -0.262 | -0.4334 | Yes |
| 81 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 12932 | -0.263 | -0.4071 | Yes |
| 82 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12969 | -0.279 | -0.3817 | Yes |
| 83 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 12984 | -0.284 | -0.3542 | Yes |
| 84 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13048 | -0.319 | -0.3268 | Yes |
| 85 | ABI2 | ABI2 Entrez, Source | abl interactor 2 | 13159 | -0.411 | -0.2937 | Yes |
| 86 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.2496 | Yes |
| 87 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 13248 | -0.551 | -0.1974 | Yes |
| 88 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.1369 | Yes |
| 89 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13280 | -0.659 | -0.0714 | Yes |
| 90 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | 0.0030 | Yes |
