Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$E2F_Q4_01 |
| Enrichment Score (ES) | -0.5090267 |
| Normalized Enrichment Score (NES) | -1.7315468 |
| Nominal p-value | 0.0047244094 |
| FDR q-value | 0.05236587 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 37 | 0.535 | 0.0502 | No |
| 2 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 436 | 0.220 | 0.0419 | No |
| 3 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | 0.0405 | No |
| 4 | HTF9C | HTF9C Entrez, Source | - | 1256 | 0.127 | 0.0101 | No |
| 5 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1609 | 0.108 | -0.0057 | No |
| 6 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 1889 | 0.098 | -0.0171 | No |
| 7 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2243 | 0.086 | -0.0352 | No |
| 8 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 2263 | 0.086 | -0.0281 | No |
| 9 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 2318 | 0.085 | -0.0238 | No |
| 10 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 2477 | 0.080 | -0.0277 | No |
| 11 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2527 | 0.079 | -0.0236 | No |
| 12 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 2669 | 0.074 | -0.0269 | No |
| 13 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 2719 | 0.073 | -0.0233 | No |
| 14 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 2896 | 0.069 | -0.0298 | No |
| 15 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 2936 | 0.068 | -0.0260 | No |
| 16 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 3098 | 0.064 | -0.0318 | No |
| 17 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3161 | 0.063 | -0.0302 | No |
| 18 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 3274 | 0.061 | -0.0326 | No |
| 19 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 3680 | 0.052 | -0.0580 | No |
| 20 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 3701 | 0.052 | -0.0544 | No |
| 21 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 3750 | 0.051 | -0.0530 | No |
| 22 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 3898 | 0.048 | -0.0593 | No |
| 23 | XTP3TPA | XTP3TPA Entrez, Source | - | 4144 | 0.044 | -0.0734 | No |
| 24 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4335 | 0.040 | -0.0837 | No |
| 25 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 4353 | 0.040 | -0.0810 | No |
| 26 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5066 | 0.028 | -0.1319 | No |
| 27 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 5107 | 0.028 | -0.1322 | No |
| 28 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 5188 | 0.026 | -0.1356 | No |
| 29 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 5597 | 0.020 | -0.1644 | No |
| 30 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5968 | 0.015 | -0.1909 | No |
| 31 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5972 | 0.015 | -0.1897 | No |
| 32 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 6036 | 0.014 | -0.1931 | No |
| 33 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 6063 | 0.013 | -0.1937 | No |
| 34 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 6476 | 0.007 | -0.2241 | No |
| 35 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 6623 | 0.005 | -0.2346 | No |
| 36 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 6857 | 0.002 | -0.2520 | No |
| 37 | NCL | NCL Entrez, Source | nucleolin | 6959 | 0.000 | -0.2596 | No |
| 38 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | -0.2601 | No |
| 39 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 7147 | -0.002 | -0.2734 | No |
| 40 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 7175 | -0.003 | -0.2751 | No |
| 41 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7214 | -0.003 | -0.2777 | No |
| 42 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 7575 | -0.009 | -0.3040 | No |
| 43 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 7648 | -0.010 | -0.3085 | No |
| 44 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 8004 | -0.015 | -0.3337 | No |
| 45 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 8170 | -0.017 | -0.3445 | No |
| 46 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 8231 | -0.019 | -0.3471 | No |
| 47 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 8430 | -0.022 | -0.3599 | No |
| 48 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8480 | -0.023 | -0.3614 | No |
| 49 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8589 | -0.025 | -0.3671 | No |
| 50 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 8771 | -0.028 | -0.3780 | No |
| 51 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 8822 | -0.029 | -0.3789 | No |
| 52 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 8937 | -0.031 | -0.3845 | No |
| 53 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8996 | -0.032 | -0.3857 | No |
| 54 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 9235 | -0.036 | -0.4000 | No |
| 55 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 9405 | -0.040 | -0.4088 | No |
| 56 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 9519 | -0.042 | -0.4132 | No |
| 57 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9644 | -0.044 | -0.4182 | No |
| 58 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9743 | -0.047 | -0.4209 | No |
| 59 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 9778 | -0.047 | -0.4188 | No |
| 60 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9846 | -0.049 | -0.4190 | No |
| 61 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9930 | -0.051 | -0.4203 | No |
| 62 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 10624 | -0.068 | -0.4659 | No |
| 63 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11071 | -0.081 | -0.4915 | No |
| 64 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 11163 | -0.084 | -0.4900 | No |
| 65 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 11325 | -0.092 | -0.4931 | No |
| 66 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11390 | -0.094 | -0.4886 | No |
| 67 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 11622 | -0.106 | -0.4955 | No |
| 68 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 11676 | -0.108 | -0.4889 | No |
| 69 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11689 | -0.109 | -0.4790 | No |
| 70 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 12088 | -0.130 | -0.4961 | Yes |
| 71 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12107 | -0.132 | -0.4844 | Yes |
| 72 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 12376 | -0.156 | -0.4892 | Yes |
| 73 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12413 | -0.160 | -0.4761 | Yes |
| 74 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 12429 | -0.161 | -0.4613 | Yes |
| 75 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12466 | -0.166 | -0.4476 | Yes |
| 76 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12601 | -0.184 | -0.4394 | Yes |
| 77 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 12673 | -0.198 | -0.4252 | Yes |
| 78 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12929 | -0.262 | -0.4185 | Yes |
| 79 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12957 | -0.275 | -0.3933 | Yes |
| 80 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13048 | -0.319 | -0.3685 | Yes |
| 81 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13127 | -0.379 | -0.3368 | Yes |
| 82 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.2959 | Yes |
| 83 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13211 | -0.481 | -0.2487 | Yes |
| 84 | DIO3 | DIO3 Entrez, Source | deiodinase, iodothyronine, type III | 13263 | -0.580 | -0.1951 | Yes |
| 85 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.1345 | Yes |
| 86 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13280 | -0.659 | -0.0702 | Yes |
| 87 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | 0.0030 | Yes |
