Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$E2F_Q6_01 |
| Enrichment Score (ES) | -0.54722416 |
| Normalized Enrichment Score (NES) | -1.8445854 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.028291136 |
| FWER p-Value | 0.841 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | -0.0322 | No |
| 2 | HTF9C | HTF9C Entrez, Source | - | 1256 | 0.127 | -0.0611 | No |
| 3 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 1313 | 0.123 | -0.0515 | No |
| 4 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1609 | 0.108 | -0.0617 | No |
| 5 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 1889 | 0.098 | -0.0719 | No |
| 6 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 2238 | 0.087 | -0.0884 | No |
| 7 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2243 | 0.086 | -0.0791 | No |
| 8 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 2263 | 0.086 | -0.0710 | No |
| 9 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 2477 | 0.080 | -0.0781 | No |
| 10 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2527 | 0.079 | -0.0730 | No |
| 11 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 2669 | 0.074 | -0.0753 | No |
| 12 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 2896 | 0.069 | -0.0847 | No |
| 13 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 2936 | 0.068 | -0.0800 | No |
| 14 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 3098 | 0.064 | -0.0850 | No |
| 15 | SNCB | SNCB Entrez, Source | synuclein, beta | 3100 | 0.064 | -0.0779 | No |
| 16 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3161 | 0.063 | -0.0754 | No |
| 17 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 3274 | 0.061 | -0.0771 | No |
| 18 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 3701 | 0.052 | -0.1035 | No |
| 19 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 3750 | 0.051 | -0.1014 | No |
| 20 | XTP3TPA | XTP3TPA Entrez, Source | - | 4144 | 0.044 | -0.1262 | No |
| 21 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4335 | 0.040 | -0.1360 | No |
| 22 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 4353 | 0.040 | -0.1328 | No |
| 23 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5066 | 0.028 | -0.1834 | No |
| 24 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 5597 | 0.020 | -0.2211 | No |
| 25 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5968 | 0.015 | -0.2474 | No |
| 26 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5972 | 0.015 | -0.2460 | No |
| 27 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 6036 | 0.014 | -0.2492 | No |
| 28 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 6063 | 0.013 | -0.2497 | No |
| 29 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 6476 | 0.007 | -0.2800 | No |
| 30 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 6623 | 0.005 | -0.2905 | No |
| 31 | NCL | NCL Entrez, Source | nucleolin | 6959 | 0.000 | -0.3157 | No |
| 32 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | -0.3162 | No |
| 33 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 7147 | -0.002 | -0.3294 | No |
| 34 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 7175 | -0.003 | -0.3312 | No |
| 35 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7214 | -0.003 | -0.3337 | No |
| 36 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 7575 | -0.009 | -0.3599 | No |
| 37 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 7648 | -0.010 | -0.3642 | No |
| 38 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 7987 | -0.015 | -0.3881 | No |
| 39 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 8004 | -0.015 | -0.3876 | No |
| 40 | ACIN1 | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 8021 | -0.015 | -0.3871 | No |
| 41 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 8170 | -0.017 | -0.3963 | No |
| 42 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 8222 | -0.018 | -0.3981 | No |
| 43 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8319 | -0.020 | -0.4031 | No |
| 44 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 8430 | -0.022 | -0.4090 | No |
| 45 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8480 | -0.023 | -0.4102 | No |
| 46 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 8587 | -0.025 | -0.4154 | No |
| 47 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8589 | -0.025 | -0.4128 | No |
| 48 | SIAHBP1 | SIAHBP1 Entrez, Source | - | 8756 | -0.027 | -0.4222 | No |
| 49 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 8822 | -0.029 | -0.4239 | No |
| 50 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8996 | -0.032 | -0.4334 | No |
| 51 | HTR2C | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C | 9219 | -0.036 | -0.4461 | No |
| 52 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 9224 | -0.036 | -0.4424 | No |
| 53 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 9405 | -0.040 | -0.4516 | No |
| 54 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 9519 | -0.042 | -0.4554 | No |
| 55 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9644 | -0.044 | -0.4598 | No |
| 56 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9743 | -0.047 | -0.4620 | No |
| 57 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 9778 | -0.047 | -0.4593 | No |
| 58 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9846 | -0.049 | -0.4589 | No |
| 59 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 9909 | -0.050 | -0.4580 | No |
| 60 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9930 | -0.051 | -0.4539 | No |
| 61 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 10624 | -0.068 | -0.4986 | No |
| 62 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11071 | -0.081 | -0.5232 | No |
| 63 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11390 | -0.094 | -0.5367 | Yes |
| 64 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 11512 | -0.100 | -0.5347 | Yes |
| 65 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 11631 | -0.106 | -0.5318 | Yes |
| 66 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 11676 | -0.108 | -0.5231 | Yes |
| 67 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11689 | -0.109 | -0.5119 | Yes |
| 68 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 11745 | -0.111 | -0.5037 | Yes |
| 69 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 12088 | -0.130 | -0.5149 | Yes |
| 70 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12107 | -0.132 | -0.5016 | Yes |
| 71 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 12198 | -0.139 | -0.4929 | Yes |
| 72 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12269 | -0.146 | -0.4819 | Yes |
| 73 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 12376 | -0.156 | -0.4726 | Yes |
| 74 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12413 | -0.160 | -0.4575 | Yes |
| 75 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 12429 | -0.161 | -0.4406 | Yes |
| 76 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12466 | -0.166 | -0.4249 | Yes |
| 77 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12601 | -0.184 | -0.4145 | Yes |
| 78 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12929 | -0.262 | -0.4099 | Yes |
| 79 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12957 | -0.275 | -0.3813 | Yes |
| 80 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13048 | -0.319 | -0.3526 | Yes |
| 81 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13127 | -0.379 | -0.3163 | Yes |
| 82 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.2695 | Yes |
| 83 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13211 | -0.481 | -0.2164 | Yes |
| 84 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.1521 | Yes |
| 85 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13280 | -0.659 | -0.0795 | Yes |
| 86 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | 0.0030 | Yes |
