Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$GR_Q6_01 |
| Enrichment Score (ES) | -0.50651395 |
| Normalized Enrichment Score (NES) | -1.7679945 |
| Nominal p-value | 0.0015948963 |
| FDR q-value | 0.042276245 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | WNT4 | WNT4 Entrez, Source | wingless-type MMTV integration site family, member 4 | 59 | 0.482 | 0.0302 | No |
| 2 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 378 | 0.240 | 0.0235 | No |
| 3 | C6ORF66 | C6ORF66 Entrez, Source | chromosome 6 open reading frame 66 | 398 | 0.233 | 0.0388 | No |
| 4 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 800 | 0.163 | 0.0202 | No |
| 5 | SV2B | SV2B Entrez, Source | synaptic vesicle glycoprotein 2B | 814 | 0.161 | 0.0308 | No |
| 6 | FANK1 | FANK1 Entrez, Source | fibronectin type III and ankyrin repeat domains 1 | 815 | 0.161 | 0.0424 | No |
| 7 | AKAP5 | AKAP5 Entrez, Source | A kinase (PRKA) anchor protein 5 | 1167 | 0.132 | 0.0254 | No |
| 8 | PAX3 | PAX3 Entrez, Source | paired box gene 3 (Waardenburg syndrome 1) | 1312 | 0.123 | 0.0234 | No |
| 9 | PCDH8 | PCDH8 Entrez, Source | protocadherin 8 | 1627 | 0.107 | 0.0074 | No |
| 10 | OTX1 | OTX1 Entrez, Source | orthodenticle homolog 1 (Drosophila) | 1813 | 0.101 | 0.0007 | No |
| 11 | GMPR2 | GMPR2 Entrez, Source | guanosine monophosphate reductase 2 | 1823 | 0.101 | 0.0073 | No |
| 12 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 1923 | 0.097 | 0.0067 | No |
| 13 | SLC18A3 | SLC18A3 Entrez, Source | solute carrier family 18 (vesicular acetylcholine), member 3 | 2076 | 0.091 | 0.0018 | No |
| 14 | NOG | NOG Entrez, Source | noggin | 2077 | 0.091 | 0.0084 | No |
| 15 | MRPS18B | MRPS18B Entrez, Source | mitochondrial ribosomal protein S18B | 2118 | 0.090 | 0.0119 | No |
| 16 | FGD4 | FGD4 Entrez, Source | FYVE, RhoGEF and PH domain containing 4 | 2178 | 0.089 | 0.0138 | No |
| 17 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 2459 | 0.081 | -0.0015 | No |
| 18 | LRRN6A | LRRN6A Entrez, Source | leucine rich repeat neuronal 6A | 2533 | 0.079 | -0.0014 | No |
| 19 | OPN1SW | OPN1SW Entrez, Source | opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) | 2654 | 0.075 | -0.0050 | No |
| 20 | TNMD | TNMD Entrez, Source | tenomodulin | 2726 | 0.073 | -0.0051 | No |
| 21 | AKAP7 | AKAP7 Entrez, Source | A kinase (PRKA) anchor protein 7 | 2928 | 0.068 | -0.0154 | No |
| 22 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2940 | 0.068 | -0.0114 | No |
| 23 | ZP3 | ZP3 Entrez, Source | zona pellucida glycoprotein 3 (sperm receptor) | 2988 | 0.067 | -0.0101 | No |
| 24 | MPZ | MPZ Entrez, Source | myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) | 3019 | 0.066 | -0.0076 | No |
| 25 | DND1 | DND1 Entrez, Source | dead end homolog 1 (zebrafish) | 3106 | 0.064 | -0.0095 | No |
| 26 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 3378 | 0.058 | -0.0257 | No |
| 27 | EYA2 | EYA2 Entrez, Source | eyes absent homolog 2 (Drosophila) | 3402 | 0.058 | -0.0233 | No |
| 28 | KCNK10 | KCNK10 Entrez, Source | potassium channel, subfamily K, member 10 | 3406 | 0.058 | -0.0194 | No |
| 29 | AQP4 | AQP4 Entrez, Source | aquaporin 4 | 3431 | 0.057 | -0.0171 | No |
| 30 | CSNK1G1 | CSNK1G1 Entrez, Source | casein kinase 1, gamma 1 | 3501 | 0.056 | -0.0183 | No |
| 31 | PPP1R10 | PPP1R10 Entrez, Source | protein phosphatase 1, regulatory subunit 10 | 4035 | 0.046 | -0.0552 | No |
| 32 | TMEM24 | TMEM24 Entrez, Source | transmembrane protein 24 | 4242 | 0.042 | -0.0678 | No |
| 33 | EIF2B4 | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 4558 | 0.037 | -0.0889 | No |
| 34 | PPM1B | PPM1B Entrez, Source | protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform | 4644 | 0.035 | -0.0928 | No |
| 35 | APBA1 | APBA1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) | 5106 | 0.028 | -0.1256 | No |
| 36 | HOXA2 | HOXA2 Entrez, Source | homeobox A2 | 5318 | 0.024 | -0.1398 | No |
| 37 | ZNF24 | ZNF24 Entrez, Source | zinc finger protein 24 | 5969 | 0.015 | -0.1879 | No |
| 38 | GRP | GRP Entrez, Source | gastrin-releasing peptide | 6132 | 0.012 | -0.1992 | No |
| 39 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 6538 | 0.006 | -0.2294 | No |
| 40 | ARG2 | ARG2 Entrez, Source | arginase, type II | 6580 | 0.006 | -0.2321 | No |
| 41 | EPHA7 | EPHA7 Entrez, Source | EPH receptor A7 | 6653 | 0.005 | -0.2372 | No |
| 42 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 6998 | -0.000 | -0.2632 | No |
| 43 | ST13 | ST13 Entrez, Source | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 7031 | -0.001 | -0.2656 | No |
| 44 | CPA3 | CPA3 Entrez, Source | carboxypeptidase A3 (mast cell) | 7058 | -0.001 | -0.2674 | No |
| 45 | LTBP3 | LTBP3 Entrez, Source | latent transforming growth factor beta binding protein 3 | 7258 | -0.004 | -0.2822 | No |
| 46 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 7574 | -0.009 | -0.3054 | No |
| 47 | SIX1 | SIX1 Entrez, Source | sine oculis homeobox homolog 1 (Drosophila) | 7671 | -0.010 | -0.3119 | No |
| 48 | PDYN | PDYN Entrez, Source | prodynorphin | 7765 | -0.011 | -0.3181 | No |
| 49 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 7948 | -0.014 | -0.3308 | No |
| 50 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 8004 | -0.015 | -0.3339 | No |
| 51 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 8105 | -0.016 | -0.3403 | No |
| 52 | RBX1 | RBX1 Entrez, Source | ring-box 1 | 8219 | -0.018 | -0.3475 | No |
| 53 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 8311 | -0.020 | -0.3529 | No |
| 54 | PDAP1 | PDAP1 Entrez, Source | PDGFA associated protein 1 | 8543 | -0.024 | -0.3687 | No |
| 55 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 8561 | -0.024 | -0.3682 | No |
| 56 | NEDD8 | NEDD8 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 8 | 8682 | -0.026 | -0.3754 | No |
| 57 | EIF4G2 | EIF4G2 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 2 | 8954 | -0.031 | -0.3936 | No |
| 58 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 9195 | -0.035 | -0.4092 | No |
| 59 | RTKN | RTKN Entrez, Source | rhotekin | 9437 | -0.040 | -0.4245 | No |
| 60 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 9534 | -0.042 | -0.4287 | No |
| 61 | SLC38A2 | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 9549 | -0.043 | -0.4267 | No |
| 62 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 9737 | -0.046 | -0.4375 | No |
| 63 | KLHL5 | KLHL5 Entrez, Source | kelch-like 5 (Drosophila) | 9873 | -0.049 | -0.4442 | No |
| 64 | NPEPPS | NPEPPS Entrez, Source | aminopeptidase puromycin sensitive | 9910 | -0.050 | -0.4433 | No |
| 65 | NCDN | NCDN Entrez, Source | neurochondrin | 10110 | -0.055 | -0.4544 | No |
| 66 | ABCG8 | ABCG8 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2) | 10112 | -0.055 | -0.4505 | No |
| 67 | RND1 | RND1 Entrez, Source | Rho family GTPase 1 | 10116 | -0.055 | -0.4468 | No |
| 68 | MYH4 | MYH4 Entrez, Source | myosin, heavy chain 4, skeletal muscle | 10619 | -0.067 | -0.4799 | No |
| 69 | MAGED1 | MAGED1 Entrez, Source | melanoma antigen family D, 1 | 10946 | -0.077 | -0.4990 | No |
| 70 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 11002 | -0.079 | -0.4975 | No |
| 71 | PACSIN3 | PACSIN3 Entrez, Source | protein kinase C and casein kinase substrate in neurons 3 | 11061 | -0.081 | -0.4961 | No |
| 72 | BAT4 | BAT4 Entrez, Source | HLA-B associated transcript 4 | 11200 | -0.086 | -0.5003 | Yes |
| 73 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 11249 | -0.088 | -0.4976 | Yes |
| 74 | SNX17 | SNX17 Entrez, Source | sorting nexin 17 | 11257 | -0.088 | -0.4918 | Yes |
| 75 | LGI1 | LGI1 Entrez, Source | leucine-rich, glioma inactivated 1 | 11315 | -0.091 | -0.4895 | Yes |
| 76 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 11411 | -0.095 | -0.4899 | Yes |
| 77 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 11508 | -0.100 | -0.4899 | Yes |
| 78 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 11520 | -0.100 | -0.4835 | Yes |
| 79 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 11588 | -0.104 | -0.4811 | Yes |
| 80 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 11593 | -0.104 | -0.4740 | Yes |
| 81 | OTX2 | OTX2 Entrez, Source | orthodenticle homolog 2 (Drosophila) | 11767 | -0.112 | -0.4790 | Yes |
| 82 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11886 | -0.118 | -0.4794 | Yes |
| 83 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 11893 | -0.118 | -0.4713 | Yes |
| 84 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 12002 | -0.125 | -0.4705 | Yes |
| 85 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12184 | -0.138 | -0.4742 | Yes |
| 86 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 12204 | -0.140 | -0.4656 | Yes |
| 87 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 12239 | -0.143 | -0.4579 | Yes |
| 88 | CAMLG | CAMLG Entrez, Source | calcium modulating ligand | 12277 | -0.146 | -0.4502 | Yes |
| 89 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 12319 | -0.150 | -0.4425 | Yes |
| 90 | PLSCR3 | PLSCR3 Entrez, Source | phospholipid scramblase 3 | 12422 | -0.161 | -0.4386 | Yes |
| 91 | PROK2 | PROK2 Entrez, Source | prokineticin 2 | 12439 | -0.162 | -0.4281 | Yes |
| 92 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 12511 | -0.172 | -0.4211 | Yes |
| 93 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12629 | -0.189 | -0.4163 | Yes |
| 94 | DHX40 | DHX40 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 12647 | -0.194 | -0.4036 | Yes |
| 95 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12690 | -0.203 | -0.3922 | Yes |
| 96 | PXN | PXN Entrez, Source | paxillin | 12740 | -0.211 | -0.3807 | Yes |
| 97 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 12813 | -0.228 | -0.3697 | Yes |
| 98 | DOK1 | DOK1 Entrez, Source | docking protein 1, 62kDa (downstream of tyrosine kinase 1) | 12904 | -0.254 | -0.3582 | Yes |
| 99 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 12930 | -0.262 | -0.3412 | Yes |
| 100 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 12984 | -0.284 | -0.3248 | Yes |
| 101 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.3054 | Yes |
| 102 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 13180 | -0.438 | -0.2865 | Yes |
| 103 | GCNT3 | GCNT3 Entrez, Source | glucosaminyl (N-acetyl) transferase 3, mucin type | 13194 | -0.458 | -0.2545 | Yes |
| 104 | GPM6A | GPM6A Entrez, Source | glycoprotein M6A | 13245 | -0.543 | -0.2192 | Yes |
| 105 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13271 | -0.644 | -0.1747 | Yes |
| 106 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | -0.1226 | Yes |
| 107 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13312 | -0.847 | -0.0623 | Yes |
| 108 | LOX | LOX Entrez, Source | lysyl oxidase | 13315 | -0.896 | 0.0020 | Yes |
