Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$HNF4_01 |
| Enrichment Score (ES) | 0.38687497 |
| Normalized Enrichment Score (NES) | 1.5119243 |
| Nominal p-value | 0.0027777778 |
| FDR q-value | 0.11458507 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 31 | 0.561 | 0.0421 | Yes |
| 2 | APOM | APOM Entrez, Source | apolipoprotein M | 113 | 0.401 | 0.0677 | Yes |
| 3 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 129 | 0.383 | 0.0970 | Yes |
| 4 | SLC25A25 | SLC25A25 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 | 132 | 0.380 | 0.1270 | Yes |
| 5 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 214 | 0.304 | 0.1450 | Yes |
| 6 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 230 | 0.293 | 0.1671 | Yes |
| 7 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 243 | 0.289 | 0.1890 | Yes |
| 8 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 296 | 0.267 | 0.2063 | Yes |
| 9 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 320 | 0.260 | 0.2252 | Yes |
| 10 | F10 | F10 Entrez, Source | coagulation factor X | 342 | 0.251 | 0.2435 | Yes |
| 11 | INHBC | INHBC Entrez, Source | inhibin, beta C | 369 | 0.242 | 0.2607 | Yes |
| 12 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 406 | 0.229 | 0.2761 | Yes |
| 13 | PEX16 | PEX16 Entrez, Source | peroxisomal biogenesis factor 16 | 421 | 0.224 | 0.2928 | Yes |
| 14 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 583 | 0.188 | 0.2956 | Yes |
| 15 | ERBB3 | ERBB3 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 588 | 0.187 | 0.3101 | Yes |
| 16 | ETFDH | ETFDH Entrez, Source | electron-transferring-flavoprotein dehydrogenase | 603 | 0.186 | 0.3238 | Yes |
| 17 | ADRB2 | ADRB2 Entrez, Source | adrenergic, beta-2-, receptor, surface | 617 | 0.184 | 0.3374 | Yes |
| 18 | NIPSNAP1 | NIPSNAP1 Entrez, Source | nipsnap homolog 1 (C. elegans) | 620 | 0.184 | 0.3518 | Yes |
| 19 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 695 | 0.174 | 0.3600 | Yes |
| 20 | ARFGEF2 | ARFGEF2 Entrez, Source | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 702 | 0.173 | 0.3732 | Yes |
| 21 | INSR | INSR Entrez, Source | insulin receptor | 735 | 0.169 | 0.3842 | Yes |
| 22 | SLC34A1 | SLC34A1 Entrez, Source | solute carrier family 34 (sodium phosphate), member 1 | 881 | 0.155 | 0.3855 | Yes |
| 23 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 1014 | 0.144 | 0.3869 | Yes |
| 24 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 1252 | 0.127 | 0.3790 | No |
| 25 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 1817 | 0.101 | 0.3443 | No |
| 26 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 2212 | 0.088 | 0.3215 | No |
| 27 | CBX7 | CBX7 Entrez, Source | chromobox homolog 7 | 2229 | 0.087 | 0.3272 | No |
| 28 | TOMM70A | TOMM70A Entrez, Source | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) | 2268 | 0.086 | 0.3311 | No |
| 29 | TBX5 | TBX5 Entrez, Source | T-box 5 | 2299 | 0.085 | 0.3356 | No |
| 30 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 2335 | 0.084 | 0.3396 | No |
| 31 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2345 | 0.084 | 0.3456 | No |
| 32 | PDZK1 | PDZK1 Entrez, Source | PDZ domain containing 1 | 2470 | 0.081 | 0.3426 | No |
| 33 | PDE8A | PDE8A Entrez, Source | phosphodiesterase 8A | 2516 | 0.079 | 0.3455 | No |
| 34 | RNF103 | RNF103 Entrez, Source | ring finger protein 103 | 2728 | 0.073 | 0.3353 | No |
| 35 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 2800 | 0.071 | 0.3356 | No |
| 36 | EPHA3 | EPHA3 Entrez, Source | EPH receptor A3 | 2824 | 0.071 | 0.3395 | No |
| 37 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 2912 | 0.069 | 0.3384 | No |
| 38 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 2972 | 0.067 | 0.3392 | No |
| 39 | HSPE1 | HSPE1 Entrez, Source | heat shock 10kDa protein 1 (chaperonin 10) | 3020 | 0.066 | 0.3409 | No |
| 40 | SNCB | SNCB Entrez, Source | synuclein, beta | 3100 | 0.064 | 0.3400 | No |
| 41 | PTBP2 | PTBP2 Entrez, Source | polypyrimidine tract binding protein 2 | 3139 | 0.064 | 0.3422 | No |
| 42 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3241 | 0.061 | 0.3394 | No |
| 43 | CNTFR | CNTFR Entrez, Source | ciliary neurotrophic factor receptor | 3340 | 0.059 | 0.3367 | No |
| 44 | AKT2 | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 3361 | 0.059 | 0.3399 | No |
| 45 | SLC25A5 | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 3418 | 0.058 | 0.3402 | No |
| 46 | TCF1 | TCF1 Entrez, Source | transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor | 3566 | 0.054 | 0.3334 | No |
| 47 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 3592 | 0.054 | 0.3358 | No |
| 48 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 3700 | 0.052 | 0.3318 | No |
| 49 | ARCN1 | ARCN1 Entrez, Source | archain 1 | 3727 | 0.051 | 0.3339 | No |
| 50 | UBE4A | UBE4A Entrez, Source | ubiquitination factor E4A (UFD2 homolog, yeast) | 3826 | 0.049 | 0.3304 | No |
| 51 | SLC22A18 | SLC22A18 Entrez, Source | solute carrier family 22 (organic cation transporter), member 18 | 3870 | 0.049 | 0.3310 | No |
| 52 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 4028 | 0.046 | 0.3228 | No |
| 53 | DAB2IP | DAB2IP Entrez, Source | DAB2 interacting protein | 4122 | 0.044 | 0.3193 | No |
| 54 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 4188 | 0.043 | 0.3178 | No |
| 55 | LRRN1 | LRRN1 Entrez, Source | leucine rich repeat neuronal 1 | 4337 | 0.040 | 0.3098 | No |
| 56 | PELO | PELO Entrez, Source | pelota homolog (Drosophila) | 4563 | 0.037 | 0.2957 | No |
| 57 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 5021 | 0.029 | 0.2634 | No |
| 58 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 5119 | 0.027 | 0.2582 | No |
| 59 | OBSCN | OBSCN Entrez, Source | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 5377 | 0.024 | 0.2406 | No |
| 60 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 5518 | 0.021 | 0.2318 | No |
| 61 | SNAP25 | SNAP25 Entrez, Source | synaptosomal-associated protein, 25kDa | 5580 | 0.021 | 0.2288 | No |
| 62 | CLCN2 | CLCN2 Entrez, Source | chloride channel 2 | 5793 | 0.017 | 0.2141 | No |
| 63 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 6026 | 0.014 | 0.1977 | No |
| 64 | DNAJA2 | DNAJA2 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 2 | 6068 | 0.013 | 0.1956 | No |
| 65 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 6072 | 0.013 | 0.1964 | No |
| 66 | TRPC5 | TRPC5 Entrez, Source | transient receptor potential cation channel, subfamily C, member 5 | 6154 | 0.012 | 0.1913 | No |
| 67 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6158 | 0.012 | 0.1920 | No |
| 68 | HSPD1 | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 6242 | 0.011 | 0.1866 | No |
| 69 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 6320 | 0.009 | 0.1815 | No |
| 70 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 6488 | 0.007 | 0.1693 | No |
| 71 | RBP2 | RBP2 Entrez, Source | retinol binding protein 2, cellular | 6542 | 0.006 | 0.1658 | No |
| 72 | NR2C2 | NR2C2 Entrez, Source | nuclear receptor subfamily 2, group C, member 2 | 6625 | 0.005 | 0.1600 | No |
| 73 | NEK6 | NEK6 Entrez, Source | NIMA (never in mitosis gene a)-related kinase 6 | 6778 | 0.003 | 0.1487 | No |
| 74 | CALB1 | CALB1 Entrez, Source | calbindin 1, 28kDa | 6894 | 0.001 | 0.1401 | No |
| 75 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 7196 | -0.003 | 0.1176 | No |
| 76 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7214 | -0.003 | 0.1166 | No |
| 77 | SLC26A3 | SLC26A3 Entrez, Source | solute carrier family 26, member 3 | 7421 | -0.006 | 0.1015 | No |
| 78 | PLEC1 | PLEC1 Entrez, Source | plectin 1, intermediate filament binding protein 500kDa | 7482 | -0.007 | 0.0975 | No |
| 79 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 7495 | -0.007 | 0.0972 | No |
| 80 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 7542 | -0.008 | 0.0944 | No |
| 81 | CACNB2 | CACNB2 Entrez, Source | calcium channel, voltage-dependent, beta 2 subunit | 8013 | -0.015 | 0.0600 | No |
| 82 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 8036 | -0.015 | 0.0596 | No |
| 83 | NET1 | NET1 Entrez, Source | neuroepithelial cell transforming gene 1 | 8186 | -0.018 | 0.0497 | No |
| 84 | PDE3B | PDE3B Entrez, Source | phosphodiesterase 3B, cGMP-inhibited | 8189 | -0.018 | 0.0510 | No |
| 85 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 8236 | -0.019 | 0.0490 | No |
| 86 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 8311 | -0.020 | 0.0450 | No |
| 87 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 8584 | -0.024 | 0.0263 | No |
| 88 | AP1B1 | AP1B1 Entrez, Source | adaptor-related protein complex 1, beta 1 subunit | 8657 | -0.026 | 0.0229 | No |
| 89 | LTB4R2 | LTB4R2 Entrez, Source | leukotriene B4 receptor 2 | 8981 | -0.032 | 0.0010 | No |
| 90 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 9043 | -0.033 | -0.0010 | No |
| 91 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 9100 | -0.034 | -0.0025 | No |
| 92 | CDX2 | CDX2 Entrez, Source | caudal type homeobox transcription factor 2 | 9221 | -0.036 | -0.0087 | No |
| 93 | FGF10 | FGF10 Entrez, Source | fibroblast growth factor 10 | 9238 | -0.037 | -0.0070 | No |
| 94 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 9431 | -0.040 | -0.0184 | No |
| 95 | SMOC1 | SMOC1 Entrez, Source | SPARC related modular calcium binding 1 | 9480 | -0.041 | -0.0187 | No |
| 96 | PIP5K2A | PIP5K2A Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type II, alpha | 9672 | -0.045 | -0.0296 | No |
| 97 | CDH6 | CDH6 Entrez, Source | cadherin 6, type 2, K-cadherin (fetal kidney) | 9721 | -0.046 | -0.0296 | No |
| 98 | SLC7A9 | SLC7A9 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | 9816 | -0.048 | -0.0328 | No |
| 99 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 10011 | -0.052 | -0.0434 | No |
| 100 | LGALS4 | LGALS4 Entrez, Source | lectin, galactoside-binding, soluble, 4 (galectin 4) | 10393 | -0.061 | -0.0673 | No |
| 101 | CHRDL1 | CHRDL1 Entrez, Source | chordin-like 1 | 10480 | -0.064 | -0.0688 | No |
| 102 | CREB3L2 | CREB3L2 Entrez, Source | cAMP responsive element binding protein 3-like 2 | 10974 | -0.078 | -0.0999 | No |
| 103 | LPL | LPL Entrez, Source | lipoprotein lipase | 10988 | -0.078 | -0.0947 | No |
| 104 | MUCDHL | MUCDHL Entrez, Source | mucin and cadherin-like | 11118 | -0.083 | -0.0979 | No |
| 105 | SS18 | SS18 Entrez, Source | synovial sarcoma translocation, chromosome 18 | 11166 | -0.084 | -0.0948 | No |
| 106 | PTMS | PTMS Entrez, Source | parathymosin | 11251 | -0.088 | -0.0941 | No |
| 107 | HR | HR Entrez, Source | hairless homolog (mouse) | 11415 | -0.095 | -0.0989 | No |
| 108 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 11508 | -0.100 | -0.0979 | No |
| 109 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 11663 | -0.108 | -0.1010 | No |
| 110 | TCF2 | TCF2 Entrez, Source | transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor | 11711 | -0.110 | -0.0959 | No |
| 111 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 12254 | -0.144 | -0.1255 | No |
| 112 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 12319 | -0.150 | -0.1184 | No |
| 113 | MARK2 | MARK2 Entrez, Source | MAP/microtubule affinity-regulating kinase 2 | 12371 | -0.155 | -0.1100 | No |
| 114 | SCT | SCT Entrez, Source | secretin | 12669 | -0.197 | -0.1168 | No |
| 115 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 12691 | -0.203 | -0.1023 | No |
| 116 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12710 | -0.207 | -0.0873 | No |
| 117 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 12812 | -0.228 | -0.0768 | No |
| 118 | TIMELESS | TIMELESS Entrez, Source | timeless homolog (Drosophila) | 12940 | -0.266 | -0.0653 | No |
| 119 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12969 | -0.279 | -0.0454 | No |
| 120 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 13173 | -0.431 | -0.0265 | No |
| 121 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 13219 | -0.495 | 0.0093 | No |
