Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classdouble_gel_72h
GeneSetV$HNF4_DR1_Q3
Enrichment Score (ES)0.43257305
Normalized Enrichment Score (NES)1.6754745
Nominal p-value0.0
FDR q-value0.043059494
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: V$HNF4_DR1_Q3   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FABP1FABP1
Entrez,  Source
fatty acid binding protein 1, liver21.1120.0903Yes
2PKLRPKLR
Entrez,  Source
pyruvate kinase, liver and RBC310.5610.1338Yes
3OTCOTC
Entrez,  Source
ornithine carbamoyltransferase440.5060.1740Yes
4LCATLCAT
Entrez,  Source
lecithin-cholesterol acyltransferase1420.3650.1964Yes
5GUCY2CGUCY2C
Entrez,  Source
guanylate cyclase 2C (heat stable enterotoxin receptor)1670.3410.2223Yes
6PRODH2PRODH2
Entrez,  Source
proline dehydrogenase (oxidase) 21690.3380.2497Yes
7PFKFB1PFKFB1
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 12300.2930.2690Yes
8FOXA3FOXA3
Entrez,  Source
forkhead box A33400.2520.2812Yes
9F10F10
Entrez,  Source
coagulation factor X3420.2510.3016Yes
10FKBP5FKBP5
Entrez,  Source
FK506 binding protein 54060.2290.3154Yes
11PEX16PEX16
Entrez,  Source
peroxisomal biogenesis factor 164210.2240.3326Yes
12POLD4POLD4
Entrez,  Source
polymerase (DNA-directed), delta 44670.2110.3464Yes
13NR1H3NR1H3
Entrez,  Source
nuclear receptor subfamily 1, group H, member 35830.1880.3529Yes
14ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)5880.1870.3679Yes
15DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)6860.1750.3748Yes
16MASP2MASP2
Entrez,  Source
mannan-binding lectin serine peptidase 27180.1710.3864Yes
17INSRINSR
Entrez,  Source
insulin receptor7350.1690.3989Yes
18HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase8190.1610.4057Yes
19SLC34A1SLC34A1
Entrez,  Source
solute carrier family 34 (sodium phosphate), member 18810.1550.4136Yes
20SHMT1SHMT1
Entrez,  Source
serine hydroxymethyltransferase 1 (soluble)9390.1500.4215Yes
21ZPBP2ZPBP2
Entrez,  Source
zona pellucida binding protein 29530.1490.4326Yes
22HIBADHHIBADH
Entrez,  Source
3-hydroxyisobutyrate dehydrogenase13840.1200.4098No
23FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)14500.1160.4143No
24F12F12
Entrez,  Source
coagulation factor XII (Hageman factor)18080.1010.3955No
25NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)18170.1010.4031No
26EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 121890.0880.3822No
27LRP1LRP1
Entrez,  Source
low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)22120.0880.3877No
28TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)22680.0860.3905No
29PDZK1PDZK1
Entrez,  Source
PDZ domain containing 124700.0810.3819No
30MRPL2MRPL2
Entrez,  Source
mitochondrial ribosomal protein L227380.0730.3676No
31GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 527430.0730.3732No
32HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)30200.0660.3577No
33SCN1ASCN1A
Entrez,  Source
sodium channel, voltage-gated, type I, alpha32190.0620.3478No
34CNTFRCNTFR
Entrez,  Source
ciliary neurotrophic factor receptor33400.0590.3435No
35KCNK10KCNK10
Entrez,  Source
potassium channel, subfamily K, member 1034060.0580.3433No
36LGI4LGI4
Entrez,  Source
leucine-rich repeat LGI family, member 435120.0560.3399No
37MRPL11MRPL11
Entrez,  Source
mitochondrial ribosomal protein L1135290.0550.3432No
38ENO3ENO3
Entrez,  Source
enolase 3 (beta, muscle)38490.0490.3231No
39TTRTTR
Entrez,  Source
transthyretin (prealbumin, amyloidosis type I)41170.0440.3065No
40DAB2IPDAB2IP
Entrez,  Source
DAB2 interacting protein41220.0440.3098No
41TMEM24TMEM24
Entrez,  Source
transmembrane protein 2442420.0420.3042No
42LRRN1LRRN1
Entrez,  Source
leucine rich repeat neuronal 143370.0400.3004No
43KLK6KLK6
Entrez,  Source
kallikrein 6 (neurosin, zyme)45080.0380.2906No
44PELOPELO
Entrez,  Source
pelota homolog (Drosophila)45630.0370.2895No
45SCAMP3SCAMP3
Entrez,  Source
secretory carrier membrane protein 348090.0320.2736No
46FXYD1FXYD1
Entrez,  Source
FXYD domain containing ion transport regulator 1 (phospholemman)48640.0320.2721No
47HSD17B8HSD17B8
Entrez,  Source
hydroxysteroid (17-beta) dehydrogenase 850000.0290.2643No
48GATA4GATA4
Entrez,  Source
GATA binding protein 450210.0290.2651No
49MSX1MSX1
Entrez,  Source
msh homeobox homolog 1 (Drosophila)50590.0280.2646No
50ESRRAESRRA
Entrez,  Source
estrogen-related receptor alpha51410.0270.2606No
51GDNFGDNF
Entrez,  Source
glial cell derived neurotrophic factor52290.0260.2562No
52CSF2CSF2
Entrez,  Source
colony stimulating factor 2 (granulocyte-macrophage)52890.0250.2537No
53GALK1GALK1
Entrez,  Source
galactokinase 153390.0240.2520No
54ITGA1ITGA1
Entrez,  Source
integrin, alpha 155180.0210.2403No
55EXOSC7EXOSC7
Entrez,  Source
exosome component 755390.0210.2405No
56SNAP25SNAP25
Entrez,  Source
synaptosomal-associated protein, 25kDa55800.0210.2391No
57CLCN2CLCN2
Entrez,  Source
chloride channel 257930.0170.2245No
58DNAJA2DNAJA2
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 260680.0130.2049No
59PGFPGF
Entrez,  Source
placental growth factor, vascular endothelial growth factor-related protein60720.0130.2057No
60AGPSAGPS
Entrez,  Source
alkylglycerone phosphate synthase60790.0130.2063No
61TP53TP53
Entrez,  Source
tumor protein p53 (Li-Fraumeni syndrome)61580.0120.2014No
62HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)62420.0110.1960No
63PABPN1PABPN1
Entrez,  Source
poly(A) binding protein, nuclear 164880.0070.1780No
64ARHGEF12ARHGEF12
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 1266880.0040.1633No
65EGR3EGR3
Entrez,  Source
early growth response 368010.0030.1550No
66IHPK2IHPK2
Entrez,  Source
inositol hexaphosphate kinase 27190-0.0030.1259No
67USP52USP52
Entrez,  Source
ubiquitin specific peptidase 527214-0.0030.1244No
68ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide7404-0.0060.1106No
69GBLGBL
Entrez,  Source
-7427-0.0060.1095No
70ZBTB12ZBTB12
Entrez,  Source
zinc finger and BTB domain containing 127461-0.0070.1075No
71PLEC1PLEC1
Entrez,  Source
plectin 1, intermediate filament binding protein 500kDa7482-0.0070.1066No
72SENP2SENP2
Entrez,  Source
SUMO1/sentrin/SMT3 specific peptidase 27539-0.0080.1030No
73CRABP2CRABP2
Entrez,  Source
cellular retinoic acid binding protein 27542-0.0080.1035No
74TREX1TREX1
Entrez,  Source
three prime repair exonuclease 17643-0.0100.0968No
75NR4A3NR4A3
Entrez,  Source
nuclear receptor subfamily 4, group A, member 37647-0.0100.0973No
76RQCD1RQCD1
Entrez,  Source
RCD1 required for cell differentiation1 homolog (S. pombe)7860-0.0130.0824No
77SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7883-0.0130.0818No
78GTF3C2GTF3C2
Entrez,  Source
general transcription factor IIIC, polypeptide 2, beta 110kDa7917-0.0140.0804No
79PPARGC1APPARGC1A
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha8036-0.0150.0727No
80NET1NET1
Entrez,  Source
neuroepithelial cell transforming gene 18186-0.0180.0629No
81PCTK1PCTK1
Entrez,  Source
PCTAIRE protein kinase 18584-0.0240.0349No
82AP1B1AP1B1
Entrez,  Source
adaptor-related protein complex 1, beta 1 subunit8657-0.0260.0315No
83SYMPKSYMPK
Entrez,  Source
symplekin8892-0.0300.0163No
84MOBPMOBP
Entrez,  Source
myelin-associated oligodendrocyte basic protein9009-0.0320.0101No
85MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 119043-0.0330.0103No
86EIF4EBP2EIF4EBP2
Entrez,  Source
eukaryotic translation initiation factor 4E binding protein 29250-0.037-0.0023No
87TREHTREH
Entrez,  Source
trehalase (brush-border membrane glycoprotein)9359-0.039-0.0073No
88SNAI1SNAI1
Entrez,  Source
snail homolog 1 (Drosophila)9442-0.040-0.0102No
89SMOC1SMOC1
Entrez,  Source
SPARC related modular calcium binding 19480-0.041-0.0096No
90LAMP2LAMP2
Entrez,  Source
lysosomal-associated membrane protein 29636-0.044-0.0178No
91LMO3LMO3
Entrez,  Source
LIM domain only 3 (rhombotin-like 2)9664-0.045-0.0162No
92BIN3BIN3
Entrez,  Source
bridging integrator 39830-0.048-0.0247No
93NR2F6NR2F6
Entrez,  Source
nuclear receptor subfamily 2, group F, member 69842-0.049-0.0216No
94HOXA5HOXA5
Entrez,  Source
homeobox A510111-0.055-0.0374No
95DCTN2DCTN2
Entrez,  Source
dynactin 2 (p50)10348-0.060-0.0504No
96GTF2IGTF2I
Entrez,  Source
general transcription factor II, i10410-0.062-0.0500No
97PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 110494-0.064-0.0510No
98STMN2STMN2
Entrez,  Source
stathmin-like 210679-0.069-0.0593No
99ZDHHC3ZDHHC3
Entrez,  Source
zinc finger, DHHC-type containing 310824-0.073-0.0643No
100ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein10891-0.075-0.0632No
101DCTN1DCTN1
Entrez,  Source
dynactin 1 (p150, glued homolog, Drosophila)10978-0.078-0.0634No
102SS18SS18
Entrez,  Source
synovial sarcoma translocation, chromosome 1811166-0.084-0.0706No
103USH1CUSH1C
Entrez,  Source
Usher syndrome 1C (autosomal recessive, severe)11196-0.086-0.0659No
104PTMSPTMS
Entrez,  Source
parathymosin11251-0.088-0.0628No
105JMJD1CJMJD1C
Entrez,  Source
jumonji domain containing 1C11508-0.100-0.0740No
106TCN2TCN2
Entrez,  Source
transcobalamin II; macrocytic anemia11593-0.104-0.0719No
107TNFRSF12ATNFRSF12A
Entrez,  Source
tumor necrosis factor receptor superfamily, member 12A11673-0.108-0.0692No
108PFN1PFN1
Entrez,  Source
profilin 111762-0.112-0.0667No
109ARHGEF7ARHGEF7
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 711790-0.113-0.0596No
110ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)12233-0.142-0.0814No
111FOXA1FOXA1
Entrez,  Source
forkhead box A112239-0.143-0.0702No
112PRKCDPRKCD
Entrez,  Source
protein kinase C, delta12254-0.144-0.0595No
113MARK2MARK2
Entrez,  Source
MAP/microtubule affinity-regulating kinase 212371-0.155-0.0557No
114PICALMPICALM
Entrez,  Source
phosphatidylinositol binding clathrin assembly protein12640-0.193-0.0603No
115RBMS1RBMS1
Entrez,  Source
RNA binding motif, single stranded interacting protein 112691-0.203-0.0476No
116SGKSGK
Entrez,  Source
serum/glucocorticoid regulated kinase12735-0.210-0.0337No
117TIMELESSTIMELESS
Entrez,  Source
timeless homolog (Drosophila)12940-0.266-0.0275No
118MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle12969-0.279-0.0069No
119PDLIM7PDLIM7
Entrez,  Source
PDZ and LIM domain 7 (enigma)13173-0.4310.0128No
Table: GSEA details [plain text format]



Fig 2: V$HNF4_DR1_Q3   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: V$HNF4_DR1_Q3: Random ES distribution   
Gene set null distribution of ES for V$HNF4_DR1_Q3