Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$SREBP1_01 |
| Enrichment Score (ES) | -0.5624287 |
| Normalized Enrichment Score (NES) | -1.8615783 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.028225629 |
| FWER p-Value | 0.768 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 445 | 0.217 | -0.0060 | No |
| 2 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 542 | 0.194 | 0.0113 | No |
| 3 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 1150 | 0.133 | -0.0175 | No |
| 4 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 2032 | 0.093 | -0.0721 | No |
| 5 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 2182 | 0.089 | -0.0721 | No |
| 6 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3058 | 0.065 | -0.1298 | No |
| 7 | CANX | CANX Entrez, Source | calnexin | 3355 | 0.059 | -0.1446 | No |
| 8 | HK2 | HK2 Entrez, Source | hexokinase 2 | 3553 | 0.055 | -0.1526 | No |
| 9 | RAB3A | RAB3A Entrez, Source | RAB3A, member RAS oncogene family | 3554 | 0.055 | -0.1456 | No |
| 10 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 3601 | 0.054 | -0.1423 | No |
| 11 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 4226 | 0.042 | -0.1839 | No |
| 12 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 4275 | 0.042 | -0.1823 | No |
| 13 | ATP6V0D1 | ATP6V0D1 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 4621 | 0.036 | -0.2037 | No |
| 14 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 5208 | 0.026 | -0.2446 | No |
| 15 | HOXA2 | HOXA2 Entrez, Source | homeobox A2 | 5318 | 0.024 | -0.2497 | No |
| 16 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5319 | 0.024 | -0.2466 | No |
| 17 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 5354 | 0.024 | -0.2462 | No |
| 18 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 5562 | 0.021 | -0.2591 | No |
| 19 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5676 | 0.019 | -0.2652 | No |
| 20 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 6037 | 0.014 | -0.2906 | No |
| 21 | ADCY2 | ADCY2 Entrez, Source | adenylate cyclase 2 (brain) | 6373 | 0.008 | -0.3148 | No |
| 22 | GGN | GGN Entrez, Source | gametogenetin | 6394 | 0.008 | -0.3153 | No |
| 23 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 7196 | -0.003 | -0.3753 | No |
| 24 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 7199 | -0.003 | -0.3751 | No |
| 25 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 7415 | -0.006 | -0.3905 | No |
| 26 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 7735 | -0.011 | -0.4131 | No |
| 27 | CUL5 | CUL5 Entrez, Source | cullin 5 | 7748 | -0.011 | -0.4126 | No |
| 28 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 7924 | -0.014 | -0.4240 | No |
| 29 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 8085 | -0.016 | -0.4341 | No |
| 30 | ACCN1 | ACCN1 Entrez, Source | amiloride-sensitive cation channel 1, neuronal (degenerin) | 8097 | -0.016 | -0.4328 | No |
| 31 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 8205 | -0.018 | -0.4386 | No |
| 32 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 8304 | -0.020 | -0.4435 | No |
| 33 | ZDHHC13 | ZDHHC13 Entrez, Source | zinc finger, DHHC-type containing 13 | 8436 | -0.022 | -0.4506 | No |
| 34 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 8550 | -0.024 | -0.4560 | No |
| 35 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 8615 | -0.025 | -0.4577 | No |
| 36 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 8687 | -0.026 | -0.4597 | No |
| 37 | SUPT6H | SUPT6H Entrez, Source | suppressor of Ty 6 homolog (S. cerevisiae) | 8801 | -0.028 | -0.4647 | No |
| 38 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 9118 | -0.034 | -0.4841 | No |
| 39 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 9179 | -0.035 | -0.4842 | No |
| 40 | DAZAP2 | DAZAP2 Entrez, Source | DAZ associated protein 2 | 9364 | -0.039 | -0.4931 | No |
| 41 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 9442 | -0.040 | -0.4938 | No |
| 42 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 9448 | -0.041 | -0.4891 | No |
| 43 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 9683 | -0.045 | -0.5010 | No |
| 44 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 9688 | -0.045 | -0.4955 | No |
| 45 | BAX | BAX Entrez, Source | BCL2-associated X protein | 9773 | -0.047 | -0.4959 | No |
| 46 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 10033 | -0.053 | -0.5087 | No |
| 47 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 10118 | -0.055 | -0.5081 | No |
| 48 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 10318 | -0.060 | -0.5155 | No |
| 49 | PDCD6IP | PDCD6IP Entrez, Source | programmed cell death 6 interacting protein | 10508 | -0.064 | -0.5216 | No |
| 50 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 10722 | -0.070 | -0.5287 | No |
| 51 | PIP5K1A | PIP5K1A Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 11170 | -0.084 | -0.5517 | Yes |
| 52 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 11219 | -0.087 | -0.5444 | Yes |
| 53 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 11249 | -0.088 | -0.5354 | Yes |
| 54 | SNX16 | SNX16 Entrez, Source | sorting nexin 16 | 11420 | -0.096 | -0.5361 | Yes |
| 55 | BLNK | BLNK Entrez, Source | B-cell linker | 11422 | -0.096 | -0.5240 | Yes |
| 56 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11474 | -0.098 | -0.5154 | Yes |
| 57 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 11499 | -0.099 | -0.5046 | Yes |
| 58 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11527 | -0.101 | -0.4939 | Yes |
| 59 | CAMK2D | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | 11618 | -0.105 | -0.4874 | Yes |
| 60 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 12016 | -0.126 | -0.5013 | Yes |
| 61 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12086 | -0.130 | -0.4900 | Yes |
| 62 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 12602 | -0.184 | -0.5054 | Yes |
| 63 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 12640 | -0.193 | -0.4838 | Yes |
| 64 | STX6 | STX6 Entrez, Source | syntaxin 6 | 12878 | -0.244 | -0.4707 | Yes |
| 65 | GRN | GRN Entrez, Source | granulin | 12966 | -0.278 | -0.4421 | Yes |
| 66 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 13090 | -0.347 | -0.4074 | Yes |
| 67 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13166 | -0.425 | -0.3592 | Yes |
| 68 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13183 | -0.443 | -0.3043 | Yes |
| 69 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13218 | -0.493 | -0.2444 | Yes |
| 70 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13242 | -0.532 | -0.1788 | Yes |
| 71 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 13291 | -0.715 | -0.0919 | Yes |
| 72 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | 0.0030 | Yes |
