Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$SRF_C |
| Enrichment Score (ES) | -0.6034323 |
| Normalized Enrichment Score (NES) | -2.1167142 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0012366308 |
| FWER p-Value | 0.017 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.284 | 0.0695 | No |
| 2 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 180 | 0.328 | 0.0737 | No |
| 3 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 437 | 0.219 | 0.0662 | No |
| 4 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 681 | 0.176 | 0.0574 | No |
| 5 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | 0.0665 | No |
| 6 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 829 | 0.160 | 0.0644 | No |
| 7 | IER2 | IER2 Entrez, Source | immediate early response 2 | 833 | 0.159 | 0.0728 | No |
| 8 | POU3F4 | POU3F4 Entrez, Source | POU domain, class 3, transcription factor 4 | 1182 | 0.131 | 0.0537 | No |
| 9 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 1487 | 0.114 | 0.0369 | No |
| 10 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 1733 | 0.104 | 0.0240 | No |
| 11 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 1814 | 0.101 | 0.0234 | No |
| 12 | RGS3 | RGS3 Entrez, Source | regulator of G-protein signalling 3 | 1991 | 0.094 | 0.0152 | No |
| 13 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 2225 | 0.087 | 0.0023 | No |
| 14 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 2231 | 0.087 | 0.0066 | No |
| 15 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 2291 | 0.085 | 0.0068 | No |
| 16 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 2370 | 0.083 | 0.0054 | No |
| 17 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 2854 | 0.070 | -0.0273 | No |
| 18 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 2897 | 0.069 | -0.0268 | No |
| 19 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 2929 | 0.068 | -0.0254 | No |
| 20 | EGR4 | EGR4 Entrez, Source | early growth response 4 | 3054 | 0.065 | -0.0312 | No |
| 21 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 4346 | 0.040 | -0.1266 | No |
| 22 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 4357 | 0.040 | -0.1252 | No |
| 23 | JPH2 | JPH2 Entrez, Source | junctophilin 2 | 4515 | 0.038 | -0.1350 | No |
| 24 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 4806 | 0.032 | -0.1552 | No |
| 25 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 5107 | 0.028 | -0.1764 | No |
| 26 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5275 | 0.025 | -0.1876 | No |
| 27 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5319 | 0.024 | -0.1896 | No |
| 28 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 5523 | 0.021 | -0.2037 | No |
| 29 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 5630 | 0.020 | -0.2107 | No |
| 30 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 6270 | 0.010 | -0.2584 | No |
| 31 | GGN | GGN Entrez, Source | gametogenetin | 6394 | 0.008 | -0.2673 | No |
| 32 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 6441 | 0.007 | -0.2704 | No |
| 33 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 6721 | 0.004 | -0.2912 | No |
| 34 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 6725 | 0.004 | -0.2913 | No |
| 35 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 6801 | 0.003 | -0.2968 | No |
| 36 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 6851 | 0.002 | -0.3004 | No |
| 37 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 7002 | -0.000 | -0.3117 | No |
| 38 | PNKP | PNKP Entrez, Source | polynucleotide kinase 3'-phosphatase | 7068 | -0.001 | -0.3166 | No |
| 39 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 7116 | -0.002 | -0.3200 | No |
| 40 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7214 | -0.003 | -0.3272 | No |
| 41 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 7348 | -0.005 | -0.3369 | No |
| 42 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7382 | -0.006 | -0.3391 | No |
| 43 | IL17B | IL17B Entrez, Source | interleukin 17B | 7417 | -0.006 | -0.3413 | No |
| 44 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 7577 | -0.009 | -0.3529 | No |
| 45 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 7793 | -0.012 | -0.3685 | No |
| 46 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 7827 | -0.013 | -0.3703 | No |
| 47 | GFPT2 | GFPT2 Entrez, Source | glutamine-fructose-6-phosphate transaminase 2 | 7852 | -0.013 | -0.3714 | No |
| 48 | PRKAB2 | PRKAB2 Entrez, Source | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 7945 | -0.014 | -0.3776 | No |
| 49 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 7948 | -0.014 | -0.3770 | No |
| 50 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 8051 | -0.016 | -0.3838 | No |
| 51 | MATR3 | MATR3 Entrez, Source | matrin 3 | 8066 | -0.016 | -0.3840 | No |
| 52 | MYO1B | MYO1B Entrez, Source | myosin IB | 8141 | -0.017 | -0.3887 | No |
| 53 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 8175 | -0.018 | -0.3903 | No |
| 54 | CKM | CKM Entrez, Source | creatine kinase, muscle | 8557 | -0.024 | -0.4178 | No |
| 55 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 8587 | -0.025 | -0.4186 | No |
| 56 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 8754 | -0.027 | -0.4297 | No |
| 57 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 8798 | -0.028 | -0.4314 | No |
| 58 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 9010 | -0.032 | -0.4456 | No |
| 59 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9062 | -0.033 | -0.4477 | No |
| 60 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9430 | -0.040 | -0.4732 | No |
| 61 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 9531 | -0.042 | -0.4785 | No |
| 62 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 9794 | -0.048 | -0.4957 | No |
| 63 | TITF1 | TITF1 Entrez, Source | thyroid transcription factor 1 | 10088 | -0.054 | -0.5149 | No |
| 64 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 10111 | -0.055 | -0.5136 | No |
| 65 | DAPK3 | DAPK3 Entrez, Source | death-associated protein kinase 3 | 10672 | -0.069 | -0.5522 | No |
| 66 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 11274 | -0.089 | -0.5928 | No |
| 67 | RNF39 | RNF39 Entrez, Source | ring finger protein 39 | 11416 | -0.095 | -0.5983 | Yes |
| 68 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 11453 | -0.098 | -0.5957 | Yes |
| 69 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 11475 | -0.099 | -0.5920 | Yes |
| 70 | ACTB | ACTB Entrez, Source | actin, beta | 11552 | -0.102 | -0.5922 | Yes |
| 71 | RASD2 | RASD2 Entrez, Source | RASD family, member 2 | 11574 | -0.103 | -0.5882 | Yes |
| 72 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 11625 | -0.106 | -0.5863 | Yes |
| 73 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 11708 | -0.110 | -0.5866 | Yes |
| 74 | TCF2 | TCF2 Entrez, Source | transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor | 11711 | -0.110 | -0.5808 | Yes |
| 75 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 11724 | -0.110 | -0.5757 | Yes |
| 76 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 11745 | -0.111 | -0.5712 | Yes |
| 77 | PFN1 | PFN1 Entrez, Source | profilin 1 | 11762 | -0.112 | -0.5664 | Yes |
| 78 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 11764 | -0.112 | -0.5604 | Yes |
| 79 | MCAM | MCAM Entrez, Source | melanoma cell adhesion molecule | 11953 | -0.122 | -0.5680 | Yes |
| 80 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11979 | -0.123 | -0.5632 | Yes |
| 81 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 12015 | -0.126 | -0.5590 | Yes |
| 82 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 12212 | -0.140 | -0.5662 | Yes |
| 83 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12269 | -0.146 | -0.5626 | Yes |
| 84 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 12273 | -0.146 | -0.5549 | Yes |
| 85 | SSH3 | SSH3 Entrez, Source | slingshot homolog 3 (Drosophila) | 12401 | -0.158 | -0.5560 | Yes |
| 86 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 12641 | -0.193 | -0.5636 | Yes |
| 87 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 12657 | -0.196 | -0.5542 | Yes |
| 88 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12690 | -0.203 | -0.5456 | Yes |
| 89 | PLN | PLN Entrez, Source | phospholamban | 12709 | -0.206 | -0.5358 | Yes |
| 90 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12710 | -0.207 | -0.5246 | Yes |
| 91 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12715 | -0.208 | -0.5136 | Yes |
| 92 | MYO1E | MYO1E Entrez, Source | myosin IE | 12726 | -0.209 | -0.5031 | Yes |
| 93 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12779 | -0.218 | -0.4952 | Yes |
| 94 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12826 | -0.231 | -0.4862 | Yes |
| 95 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 12828 | -0.232 | -0.4737 | Yes |
| 96 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 13035 | -0.310 | -0.4725 | Yes |
| 97 | DNAJB4 | DNAJB4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 4 | 13141 | -0.392 | -0.4592 | Yes |
| 98 | POPDC2 | POPDC2 Entrez, Source | popeye domain containing 2 | 13157 | -0.411 | -0.4381 | Yes |
| 99 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13166 | -0.425 | -0.4157 | Yes |
| 100 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 13171 | -0.429 | -0.3928 | Yes |
| 101 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 13173 | -0.431 | -0.3696 | Yes |
| 102 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 13229 | -0.509 | -0.3462 | Yes |
| 103 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13279 | -0.655 | -0.3145 | Yes |
| 104 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13300 | -0.747 | -0.2756 | Yes |
| 105 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13312 | -0.847 | -0.2306 | Yes |
| 106 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13334 | -1.240 | -0.1651 | Yes |
| 107 | TAGLN | TAGLN Entrez, Source | transgelin | 13339 | -1.475 | -0.0856 | Yes |
| 108 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
