Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$SRF_Q4 |
| Enrichment Score (ES) | -0.52497375 |
| Normalized Enrichment Score (NES) | -1.8728359 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.026320614 |
| FWER p-Value | 0.718 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.284 | 0.0704 | No |
| 2 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 180 | 0.328 | 0.0749 | No |
| 3 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 214 | 0.304 | 0.0890 | No |
| 4 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 329 | 0.257 | 0.0945 | No |
| 5 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 437 | 0.219 | 0.0984 | No |
| 6 | FGF17 | FGF17 Entrez, Source | fibroblast growth factor 17 | 538 | 0.195 | 0.1015 | No |
| 7 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 681 | 0.176 | 0.1004 | No |
| 8 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | 0.1097 | No |
| 9 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 829 | 0.160 | 0.1078 | No |
| 10 | IER2 | IER2 Entrez, Source | immediate early response 2 | 833 | 0.159 | 0.1163 | No |
| 11 | POU3F4 | POU3F4 Entrez, Source | POU domain, class 3, transcription factor 4 | 1182 | 0.131 | 0.0972 | No |
| 12 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 1487 | 0.114 | 0.0804 | No |
| 13 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 1733 | 0.104 | 0.0676 | No |
| 14 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 1814 | 0.101 | 0.0671 | No |
| 15 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 2225 | 0.087 | 0.0408 | No |
| 16 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 2231 | 0.087 | 0.0452 | No |
| 17 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 2291 | 0.085 | 0.0455 | No |
| 18 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 2370 | 0.083 | 0.0441 | No |
| 19 | TNMD | TNMD Entrez, Source | tenomodulin | 2726 | 0.073 | 0.0213 | No |
| 20 | COL23A1 | COL23A1 Entrez, Source | collagen, type XXIII, alpha 1 | 2873 | 0.070 | 0.0141 | No |
| 21 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 2927 | 0.068 | 0.0138 | No |
| 22 | EGR4 | EGR4 Entrez, Source | early growth response 4 | 3054 | 0.065 | 0.0079 | No |
| 23 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 3206 | 0.062 | -0.0002 | No |
| 24 | SND1 | SND1 Entrez, Source | - | 3230 | 0.062 | 0.0015 | No |
| 25 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 3478 | 0.056 | -0.0141 | No |
| 26 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 3592 | 0.054 | -0.0197 | No |
| 27 | SRP54 | SRP54 Entrez, Source | signal recognition particle 54kDa | 4189 | 0.043 | -0.0624 | No |
| 28 | JPH2 | JPH2 Entrez, Source | junctophilin 2 | 4515 | 0.038 | -0.0849 | No |
| 29 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 4806 | 0.032 | -0.1051 | No |
| 30 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 5030 | 0.029 | -0.1204 | No |
| 31 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 5059 | 0.028 | -0.1209 | No |
| 32 | SORT1 | SORT1 Entrez, Source | sortilin 1 | 5081 | 0.028 | -0.1210 | No |
| 33 | NLGN3 | NLGN3 Entrez, Source | neuroligin 3 | 5114 | 0.027 | -0.1219 | No |
| 34 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 5141 | 0.027 | -0.1224 | No |
| 35 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5275 | 0.025 | -0.1311 | No |
| 36 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5319 | 0.024 | -0.1330 | No |
| 37 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 5375 | 0.024 | -0.1359 | No |
| 38 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 5523 | 0.021 | -0.1458 | No |
| 39 | KCNJ13 | KCNJ13 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 13 | 5568 | 0.021 | -0.1480 | No |
| 40 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 6270 | 0.010 | -0.2004 | No |
| 41 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 6441 | 0.007 | -0.2129 | No |
| 42 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 6721 | 0.004 | -0.2338 | No |
| 43 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 6725 | 0.004 | -0.2338 | No |
| 44 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 6801 | 0.003 | -0.2393 | No |
| 45 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 6851 | 0.002 | -0.2429 | No |
| 46 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 7002 | -0.000 | -0.2543 | No |
| 47 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 7116 | -0.002 | -0.2627 | No |
| 48 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 7348 | -0.005 | -0.2799 | No |
| 49 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7382 | -0.006 | -0.2821 | No |
| 50 | IL17B | IL17B Entrez, Source | interleukin 17B | 7417 | -0.006 | -0.2843 | No |
| 51 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 7577 | -0.009 | -0.2958 | No |
| 52 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 7827 | -0.013 | -0.3140 | No |
| 53 | DGKG | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 7914 | -0.014 | -0.3197 | No |
| 54 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 7962 | -0.014 | -0.3225 | No |
| 55 | MYO1B | MYO1B Entrez, Source | myosin IB | 8141 | -0.017 | -0.3350 | No |
| 56 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 8175 | -0.018 | -0.3366 | No |
| 57 | CKM | CKM Entrez, Source | creatine kinase, muscle | 8557 | -0.024 | -0.3640 | No |
| 58 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 8587 | -0.025 | -0.3649 | No |
| 59 | GAB2 | GAB2 Entrez, Source | GRB2-associated binding protein 2 | 8676 | -0.026 | -0.3701 | No |
| 60 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 8754 | -0.027 | -0.3744 | No |
| 61 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 8798 | -0.028 | -0.3762 | No |
| 62 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 8973 | -0.032 | -0.3876 | No |
| 63 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 9010 | -0.032 | -0.3885 | No |
| 64 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9062 | -0.033 | -0.3906 | No |
| 65 | CRH | CRH Entrez, Source | corticotropin releasing hormone | 9147 | -0.035 | -0.3950 | No |
| 66 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 9244 | -0.037 | -0.4002 | No |
| 67 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 9252 | -0.037 | -0.3988 | No |
| 68 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 9406 | -0.040 | -0.4081 | No |
| 69 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 9531 | -0.042 | -0.4152 | No |
| 70 | TAF5L | TAF5L Entrez, Source | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 9912 | -0.050 | -0.4412 | No |
| 71 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 10111 | -0.055 | -0.4532 | No |
| 72 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 10336 | -0.060 | -0.4668 | No |
| 73 | RIMS1 | RIMS1 Entrez, Source | regulating synaptic membrane exocytosis 1 | 10964 | -0.077 | -0.5100 | No |
| 74 | IHPK1 | IHPK1 Entrez, Source | inositol hexaphosphate kinase 1 | 11145 | -0.083 | -0.5190 | No |
| 75 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 11225 | -0.087 | -0.5202 | Yes |
| 76 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 11274 | -0.089 | -0.5190 | Yes |
| 77 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 11325 | -0.092 | -0.5177 | Yes |
| 78 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11390 | -0.094 | -0.5174 | Yes |
| 79 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 11453 | -0.098 | -0.5167 | Yes |
| 80 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 11475 | -0.099 | -0.5129 | Yes |
| 81 | RERE | RERE Entrez, Source | arginine-glutamic acid dipeptide (RE) repeats | 11485 | -0.099 | -0.5082 | Yes |
| 82 | ACTB | ACTB Entrez, Source | actin, beta | 11552 | -0.102 | -0.5076 | Yes |
| 83 | RASD2 | RASD2 Entrez, Source | RASD family, member 2 | 11574 | -0.103 | -0.5035 | Yes |
| 84 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 11603 | -0.105 | -0.4999 | Yes |
| 85 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 11625 | -0.106 | -0.4957 | Yes |
| 86 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 11727 | -0.110 | -0.4973 | Yes |
| 87 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 11745 | -0.111 | -0.4925 | Yes |
| 88 | PFN1 | PFN1 Entrez, Source | profilin 1 | 11762 | -0.112 | -0.4875 | Yes |
| 89 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 11764 | -0.112 | -0.4815 | Yes |
| 90 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11886 | -0.118 | -0.4841 | Yes |
| 91 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11979 | -0.123 | -0.4843 | Yes |
| 92 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 12212 | -0.140 | -0.4942 | Yes |
| 93 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 12273 | -0.146 | -0.4907 | Yes |
| 94 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12313 | -0.149 | -0.4855 | Yes |
| 95 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 12319 | -0.150 | -0.4776 | Yes |
| 96 | TMOD1 | TMOD1 Entrez, Source | tropomodulin 1 | 12458 | -0.165 | -0.4790 | Yes |
| 97 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 12570 | -0.180 | -0.4775 | Yes |
| 98 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12629 | -0.189 | -0.4715 | Yes |
| 99 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 12657 | -0.196 | -0.4628 | Yes |
| 100 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12690 | -0.203 | -0.4541 | Yes |
| 101 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12710 | -0.207 | -0.4442 | Yes |
| 102 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12715 | -0.208 | -0.4331 | Yes |
| 103 | MYO1E | MYO1E Entrez, Source | myosin IE | 12726 | -0.209 | -0.4224 | Yes |
| 104 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12735 | -0.210 | -0.4115 | Yes |
| 105 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12779 | -0.218 | -0.4028 | Yes |
| 106 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.4040 | Yes |
| 107 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 13035 | -0.310 | -0.3887 | Yes |
| 108 | FST | FST Entrez, Source | follistatin | 13045 | -0.318 | -0.3720 | Yes |
| 109 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 13171 | -0.429 | -0.3579 | Yes |
| 110 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 13172 | -0.431 | -0.3343 | Yes |
| 111 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13211 | -0.481 | -0.3108 | Yes |
| 112 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13260 | -0.571 | -0.2831 | Yes |
| 113 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13279 | -0.655 | -0.2485 | Yes |
| 114 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 13290 | -0.708 | -0.2105 | Yes |
| 115 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13312 | -0.847 | -0.1656 | Yes |
| 116 | TAGLN | TAGLN Entrez, Source | transgelin | 13339 | -1.475 | -0.0868 | Yes |
| 117 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
