Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$TATA_C |
| Enrichment Score (ES) | -0.5008177 |
| Normalized Enrichment Score (NES) | -1.8540528 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02785753 |
| FWER p-Value | 0.79 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 195 | 0.312 | 0.0023 | No |
| 2 | NR5A2 | NR5A2 Entrez, Source | nuclear receptor subfamily 5, group A, member 2 | 206 | 0.307 | 0.0183 | No |
| 3 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 243 | 0.289 | 0.0314 | No |
| 4 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 355 | 0.248 | 0.0365 | No |
| 5 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 414 | 0.227 | 0.0445 | No |
| 6 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 829 | 0.160 | 0.0219 | No |
| 7 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 852 | 0.158 | 0.0288 | No |
| 8 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 1007 | 0.144 | 0.0250 | No |
| 9 | SLC12A2 | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | 1216 | 0.129 | 0.0163 | No |
| 10 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1413 | 0.118 | 0.0079 | No |
| 11 | CDC26 | CDC26 Entrez, Source | cell division cycle 26 | 1478 | 0.114 | 0.0093 | No |
| 12 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 1619 | 0.108 | 0.0046 | No |
| 13 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 1748 | 0.103 | 0.0005 | No |
| 14 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 1767 | 0.102 | 0.0048 | No |
| 15 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 1910 | 0.097 | -0.0007 | No |
| 16 | ELMO3 | ELMO3 Entrez, Source | engulfment and cell motility 3 | 1956 | 0.095 | 0.0011 | No |
| 17 | TCTA | TCTA Entrez, Source | T-cell leukemia translocation altered gene | 2008 | 0.094 | 0.0023 | No |
| 18 | MRPS18B | MRPS18B Entrez, Source | mitochondrial ribosomal protein S18B | 2118 | 0.090 | -0.0010 | No |
| 19 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 2235 | 0.087 | -0.0050 | No |
| 20 | MAPK10 | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 2261 | 0.086 | -0.0022 | No |
| 21 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 2318 | 0.085 | -0.0018 | No |
| 22 | OTP | OTP Entrez, Source | orthopedia homolog (Drosophila) | 2326 | 0.084 | 0.0023 | No |
| 23 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 2628 | 0.076 | -0.0164 | No |
| 24 | AMY2A | AMY2A Entrez, Source | amylase, alpha 2A; pancreatic | 2658 | 0.075 | -0.0145 | No |
| 25 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 2743 | 0.073 | -0.0169 | No |
| 26 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 2936 | 0.068 | -0.0277 | No |
| 27 | MYH2 | MYH2 Entrez, Source | myosin, heavy chain 2, skeletal muscle, adult | 2937 | 0.068 | -0.0240 | No |
| 28 | WDR20 | WDR20 Entrez, Source | WD repeat domain 20 | 3021 | 0.066 | -0.0267 | No |
| 29 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 3206 | 0.062 | -0.0372 | No |
| 30 | PLUNC | PLUNC Entrez, Source | palate, lung and nasal epithelium carcinoma associated | 3336 | 0.059 | -0.0438 | No |
| 31 | HAMP | HAMP Entrez, Source | hepcidin antimicrobial peptide | 3451 | 0.057 | -0.0493 | No |
| 32 | MYL2 | MYL2 Entrez, Source | myosin, light chain 2, regulatory, cardiac, slow | 3684 | 0.052 | -0.0640 | No |
| 33 | SLIT3 | SLIT3 Entrez, Source | slit homolog 3 (Drosophila) | 4012 | 0.046 | -0.0863 | No |
| 34 | PPP1R10 | PPP1R10 Entrez, Source | protein phosphatase 1, regulatory subunit 10 | 4035 | 0.046 | -0.0854 | No |
| 35 | GRM2 | GRM2 Entrez, Source | glutamate receptor, metabotropic 2 | 4198 | 0.043 | -0.0954 | No |
| 36 | FIP1L1 | FIP1L1 Entrez, Source | FIP1 like 1 (S. cerevisiae) | 4482 | 0.038 | -0.1147 | No |
| 37 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 4553 | 0.037 | -0.1180 | No |
| 38 | FSHB | FSHB Entrez, Source | follicle stimulating hormone, beta polypeptide | 4631 | 0.035 | -0.1219 | No |
| 39 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 4666 | 0.035 | -0.1226 | No |
| 40 | CITED1 | CITED1 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 4671 | 0.035 | -0.1210 | No |
| 41 | PPARGC1B | PPARGC1B Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, beta | 4699 | 0.034 | -0.1211 | No |
| 42 | JUND | JUND Entrez, Source | jun D proto-oncogene | 4934 | 0.030 | -0.1372 | No |
| 43 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 5000 | 0.029 | -0.1406 | No |
| 44 | MYH1 | MYH1 Entrez, Source | myosin, heavy chain 1, skeletal muscle, adult | 5171 | 0.027 | -0.1520 | No |
| 45 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5319 | 0.024 | -0.1618 | No |
| 46 | PRPF4 | PRPF4 Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog (yeast) | 5385 | 0.023 | -0.1654 | No |
| 47 | GJA5 | GJA5 Entrez, Source | gap junction protein, alpha 5, 40kDa (connexin 40) | 5462 | 0.022 | -0.1700 | No |
| 48 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 5502 | 0.022 | -0.1717 | No |
| 49 | STK39 | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 5922 | 0.015 | -0.2026 | No |
| 50 | TCF4 | TCF4 Entrez, Source | transcription factor 4 | 5953 | 0.015 | -0.2041 | No |
| 51 | LMO2 | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 6039 | 0.014 | -0.2098 | No |
| 52 | CTDSP1 | CTDSP1 Entrez, Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 6119 | 0.013 | -0.2151 | No |
| 53 | NDNL2 | NDNL2 Entrez, Source | necdin-like 2 | 6451 | 0.007 | -0.2398 | No |
| 54 | DDX5 | DDX5 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 6462 | 0.007 | -0.2401 | No |
| 55 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 6476 | 0.007 | -0.2408 | No |
| 56 | RBP2 | RBP2 Entrez, Source | retinol binding protein 2, cellular | 6542 | 0.006 | -0.2454 | No |
| 57 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 6567 | 0.006 | -0.2469 | No |
| 58 | RAB15 | RAB15 Entrez, Source | RAB15, member RAS onocogene family | 6698 | 0.004 | -0.2565 | No |
| 59 | NKX6-1 | NKX6-1 Entrez, Source | NK6 transcription factor related, locus 1 (Drosophila) | 6704 | 0.004 | -0.2567 | No |
| 60 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 6721 | 0.004 | -0.2577 | No |
| 61 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 6725 | 0.004 | -0.2577 | No |
| 62 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 7147 | -0.002 | -0.2895 | No |
| 63 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 7159 | -0.002 | -0.2902 | No |
| 64 | EEF2 | EEF2 Entrez, Source | eukaryotic translation elongation factor 2 | 7448 | -0.007 | -0.3117 | No |
| 65 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 7492 | -0.007 | -0.3145 | No |
| 66 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 7542 | -0.008 | -0.3178 | No |
| 67 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 7605 | -0.009 | -0.3220 | No |
| 68 | PDYN | PDYN Entrez, Source | prodynorphin | 7765 | -0.011 | -0.3334 | No |
| 69 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 7875 | -0.013 | -0.3409 | No |
| 70 | WSB2 | WSB2 Entrez, Source | WD repeat and SOCS box-containing 2 | 7925 | -0.014 | -0.3439 | No |
| 71 | KCNK12 | KCNK12 Entrez, Source | potassium channel, subfamily K, member 12 | 8119 | -0.017 | -0.3576 | No |
| 72 | RASL11B | RASL11B Entrez, Source | RAS-like, family 11, member B | 8125 | -0.017 | -0.3571 | No |
| 73 | FGF23 | FGF23 Entrez, Source | fibroblast growth factor 23 | 8193 | -0.018 | -0.3612 | No |
| 74 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 8222 | -0.018 | -0.3623 | No |
| 75 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 8226 | -0.018 | -0.3615 | No |
| 76 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 8249 | -0.019 | -0.3621 | No |
| 77 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 8581 | -0.024 | -0.3859 | No |
| 78 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 8587 | -0.025 | -0.3849 | No |
| 79 | MYH3 | MYH3 Entrez, Source | myosin, heavy chain 3, skeletal muscle, embryonic | 8743 | -0.027 | -0.3952 | No |
| 80 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 8760 | -0.027 | -0.3949 | No |
| 81 | PHEX | PHEX Entrez, Source | phosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets) | 8792 | -0.028 | -0.3957 | No |
| 82 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 8798 | -0.028 | -0.3945 | No |
| 83 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 8953 | -0.031 | -0.4045 | No |
| 84 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 9100 | -0.034 | -0.4137 | No |
| 85 | PDGFRB | PDGFRB Entrez, Source | platelet-derived growth factor receptor, beta polypeptide | 9380 | -0.039 | -0.4327 | No |
| 86 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 9431 | -0.040 | -0.4343 | No |
| 87 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 9450 | -0.041 | -0.4334 | No |
| 88 | ESRRG | ESRRG Entrez, Source | estrogen-related receptor gamma | 9512 | -0.042 | -0.4357 | No |
| 89 | DUOX2 | DUOX2 Entrez, Source | dual oxidase 2 | 9524 | -0.042 | -0.4343 | No |
| 90 | DIO2 | DIO2 Entrez, Source | deiodinase, iodothyronine, type II | 9834 | -0.049 | -0.4550 | No |
| 91 | TWIST1 | TWIST1 Entrez, Source | twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila) | 9839 | -0.049 | -0.4527 | No |
| 92 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 9978 | -0.052 | -0.4603 | No |
| 93 | SHANK2 | SHANK2 Entrez, Source | SH3 and multiple ankyrin repeat domains 2 | 10101 | -0.054 | -0.4666 | No |
| 94 | SEMA3A | SEMA3A Entrez, Source | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 10163 | -0.056 | -0.4681 | No |
| 95 | CAPN6 | CAPN6 Entrez, Source | calpain 6 | 10215 | -0.057 | -0.4689 | No |
| 96 | NKX2-5 | NKX2-5 Entrez, Source | NK2 transcription factor related, locus 5 (Drosophila) | 10255 | -0.058 | -0.4687 | No |
| 97 | AGPAT4 | AGPAT4 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) | 10343 | -0.060 | -0.4720 | No |
| 98 | PKIA | PKIA Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 10441 | -0.063 | -0.4759 | No |
| 99 | GTF3C1 | GTF3C1 Entrez, Source | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 10574 | -0.066 | -0.4823 | No |
| 100 | MYH4 | MYH4 Entrez, Source | myosin, heavy chain 4, skeletal muscle | 10619 | -0.067 | -0.4819 | No |
| 101 | TSHB | TSHB Entrez, Source | thyroid stimulating hormone, beta | 10656 | -0.069 | -0.4809 | No |
| 102 | VIP | VIP Entrez, Source | vasoactive intestinal peptide | 10693 | -0.070 | -0.4798 | No |
| 103 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 10717 | -0.070 | -0.4777 | No |
| 104 | TRPC4 | TRPC4 Entrez, Source | transient receptor potential cation channel, subfamily C, member 4 | 10745 | -0.071 | -0.4759 | No |
| 105 | GPR50 | GPR50 Entrez, Source | G protein-coupled receptor 50 | 10758 | -0.071 | -0.4729 | No |
| 106 | KCNA3 | KCNA3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 3 | 10815 | -0.073 | -0.4732 | No |
| 107 | RHOH | RHOH Entrez, Source | ras homolog gene family, member H | 10818 | -0.073 | -0.4693 | No |
| 108 | LPL | LPL Entrez, Source | lipoprotein lipase | 10988 | -0.078 | -0.4779 | No |
| 109 | PACSIN3 | PACSIN3 Entrez, Source | protein kinase C and casein kinase substrate in neurons 3 | 11061 | -0.081 | -0.4789 | No |
| 110 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 11211 | -0.086 | -0.4855 | No |
| 111 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 11288 | -0.090 | -0.4863 | No |
| 112 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 11466 | -0.098 | -0.4944 | No |
| 113 | ACTB | ACTB Entrez, Source | actin, beta | 11552 | -0.102 | -0.4953 | Yes |
| 114 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 11603 | -0.105 | -0.4933 | Yes |
| 115 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 11663 | -0.108 | -0.4919 | Yes |
| 116 | OTX2 | OTX2 Entrez, Source | orthodenticle homolog 2 (Drosophila) | 11767 | -0.112 | -0.4936 | Yes |
| 117 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 11789 | -0.113 | -0.4890 | Yes |
| 118 | STC1 | STC1 Entrez, Source | stanniocalcin 1 | 11795 | -0.113 | -0.4832 | Yes |
| 119 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 11808 | -0.114 | -0.4779 | Yes |
| 120 | IL17F | IL17F Entrez, Source | interleukin 17F | 11826 | -0.115 | -0.4729 | Yes |
| 121 | CYB561D2 | CYB561D2 Entrez, Source | cytochrome b-561 domain containing 2 | 12022 | -0.127 | -0.4807 | Yes |
| 122 | KCNJ8 | KCNJ8 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 8 | 12077 | -0.130 | -0.4777 | Yes |
| 123 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 12109 | -0.132 | -0.4729 | Yes |
| 124 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12112 | -0.132 | -0.4658 | Yes |
| 125 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12269 | -0.146 | -0.4697 | Yes |
| 126 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12313 | -0.149 | -0.4647 | Yes |
| 127 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12397 | -0.157 | -0.4624 | Yes |
| 128 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 12657 | -0.196 | -0.4713 | Yes |
| 129 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 12812 | -0.228 | -0.4705 | Yes |
| 130 | CD96 | CD96 Entrez, Source | CD96 molecule | 12946 | -0.269 | -0.4659 | Yes |
| 131 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 12986 | -0.285 | -0.4533 | Yes |
| 132 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13042 | -0.314 | -0.4403 | Yes |
| 133 | CDC42EP2 | CDC42EP2 Entrez, Source | CDC42 effector protein (Rho GTPase binding) 2 | 13063 | -0.326 | -0.4240 | Yes |
| 134 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13210 | -0.480 | -0.4088 | Yes |
| 135 | KITLG | KITLG Entrez, Source | KIT ligand | 13215 | -0.492 | -0.3823 | Yes |
| 136 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13242 | -0.532 | -0.3552 | Yes |
| 137 | NPY | NPY Entrez, Source | neuropeptide Y | 13255 | -0.563 | -0.3253 | Yes |
| 138 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13300 | -0.747 | -0.2878 | Yes |
| 139 | LOX | LOX Entrez, Source | lysyl oxidase | 13315 | -0.896 | -0.2399 | Yes |
| 140 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | -0.1719 | Yes |
| 141 | TAGLN | TAGLN Entrez, Source | transgelin | 13339 | -1.475 | -0.0914 | Yes |
| 142 | CD24 | CD24 Entrez, Source | CD24 molecule | 13341 | -1.675 | 0.0001 | Yes |
