Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | V$ZF5_01 |
| Enrichment Score (ES) | -0.5106865 |
| Normalized Enrichment Score (NES) | -1.8042285 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.036854453 |
| FWER p-Value | 0.959 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CRY1 | CRY1 Entrez, Source | cryptochrome 1 (photolyase-like) | 734 | 0.169 | -0.0385 | No |
| 2 | SMPD3 | SMPD3 Entrez, Source | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | 1232 | 0.128 | -0.0632 | No |
| 3 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 1487 | 0.114 | -0.0709 | No |
| 4 | FUT8 | FUT8 Entrez, Source | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 1701 | 0.105 | -0.0764 | No |
| 5 | ACCN2 | ACCN2 Entrez, Source | amiloride-sensitive cation channel 2, neuronal | 1849 | 0.099 | -0.0775 | No |
| 6 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1856 | 0.099 | -0.0680 | No |
| 7 | DDIT3 | DDIT3 Entrez, Source | DNA-damage-inducible transcript 3 | 1921 | 0.097 | -0.0631 | No |
| 8 | PHOX2A | PHOX2A Entrez, Source | paired-like (aristaless) homeobox 2a | 2111 | 0.091 | -0.0683 | No |
| 9 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 2235 | 0.087 | -0.0688 | No |
| 10 | GRIK3 | GRIK3 Entrez, Source | glutamate receptor, ionotropic, kainate 3 | 2416 | 0.082 | -0.0742 | No |
| 11 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 2560 | 0.078 | -0.0771 | No |
| 12 | SYT12 | SYT12 Entrez, Source | synaptotagmin XII | 2954 | 0.067 | -0.1000 | No |
| 13 | UBE2N | UBE2N Entrez, Source | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 2977 | 0.067 | -0.0950 | No |
| 14 | NGFR | NGFR Entrez, Source | nerve growth factor receptor (TNFR superfamily, member 16) | 3208 | 0.062 | -0.1061 | No |
| 15 | CACNA1A | CACNA1A Entrez, Source | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 3272 | 0.061 | -0.1047 | No |
| 16 | NTN1 | NTN1 Entrez, Source | netrin 1 | 3284 | 0.060 | -0.0995 | No |
| 17 | GFER | GFER Entrez, Source | growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae) | 3386 | 0.058 | -0.1013 | No |
| 18 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 3412 | 0.058 | -0.0973 | No |
| 19 | ITPKA | ITPKA Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase A | 3785 | 0.050 | -0.1204 | No |
| 20 | SYT7 | SYT7 Entrez, Source | synaptotagmin VII | 3798 | 0.050 | -0.1163 | No |
| 21 | ATP10A | ATP10A Entrez, Source | ATPase, Class V, type 10A | 3936 | 0.048 | -0.1218 | No |
| 22 | NXPH4 | NXPH4 Entrez, Source | neurexophilin 4 | 4099 | 0.045 | -0.1296 | No |
| 23 | POU4F1 | POU4F1 Entrez, Source | POU domain, class 4, transcription factor 1 | 4112 | 0.044 | -0.1260 | No |
| 24 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4335 | 0.040 | -0.1387 | No |
| 25 | BTRC | BTRC Entrez, Source | beta-transducin repeat containing | 4551 | 0.037 | -0.1512 | No |
| 26 | KCND3 | KCND3 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 3 | 4705 | 0.034 | -0.1594 | No |
| 27 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 4806 | 0.032 | -0.1637 | No |
| 28 | GJB6 | GJB6 Entrez, Source | gap junction protein, beta 6 (connexin 30) | 4808 | 0.032 | -0.1605 | No |
| 29 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 5090 | 0.028 | -0.1789 | No |
| 30 | HCN4 | HCN4 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 4 | 5127 | 0.027 | -0.1789 | No |
| 31 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 5523 | 0.021 | -0.2066 | No |
| 32 | KCNC1 | KCNC1 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 1 | 5723 | 0.018 | -0.2198 | No |
| 33 | PPIE | PPIE Entrez, Source | peptidylprolyl isomerase E (cyclophilin E) | 5802 | 0.017 | -0.2239 | No |
| 34 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 6000 | 0.014 | -0.2374 | No |
| 35 | RPL41 | RPL41 Entrez, Source | ribosomal protein L41 | 6066 | 0.013 | -0.2409 | No |
| 36 | UBTF | UBTF Entrez, Source | upstream binding transcription factor, RNA polymerase I | 6260 | 0.010 | -0.2545 | No |
| 37 | DCAMKL1 | DCAMKL1 Entrez, Source | doublecortin and CaM kinase-like 1 | 6372 | 0.008 | -0.2620 | No |
| 38 | ABCC8 | ABCC8 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | 6576 | 0.006 | -0.2768 | No |
| 39 | GRIN2B | GRIN2B Entrez, Source | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 6579 | 0.006 | -0.2764 | No |
| 40 | ARHGEF12 | ARHGEF12 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 12 | 6688 | 0.004 | -0.2842 | No |
| 41 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 6779 | 0.003 | -0.2907 | No |
| 42 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 7148 | -0.002 | -0.3182 | No |
| 43 | EIF3S10 | EIF3S10 Entrez, Source | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 7170 | -0.003 | -0.3195 | No |
| 44 | KCNH5 | KCNH5 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 5 | 7342 | -0.005 | -0.3319 | No |
| 45 | UQCRH | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 7358 | -0.005 | -0.3325 | No |
| 46 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7382 | -0.006 | -0.3337 | No |
| 47 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 7648 | -0.010 | -0.3527 | No |
| 48 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 7831 | -0.013 | -0.3652 | No |
| 49 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 7871 | -0.013 | -0.3668 | No |
| 50 | DNM2 | DNM2 Entrez, Source | dynamin 2 | 7880 | -0.013 | -0.3661 | No |
| 51 | RGS7 | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 7991 | -0.015 | -0.3729 | No |
| 52 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 8221 | -0.018 | -0.3884 | No |
| 53 | SEP15 | SEP15 Entrez, Source | - | 8228 | -0.018 | -0.3870 | No |
| 54 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 8320 | -0.020 | -0.3918 | No |
| 55 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 8339 | -0.020 | -0.3911 | No |
| 56 | RNF10 | RNF10 Entrez, Source | ring finger protein 10 | 8565 | -0.024 | -0.4057 | No |
| 57 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 8587 | -0.025 | -0.4048 | No |
| 58 | RASGRF1 | RASGRF1 Entrez, Source | Ras protein-specific guanine nucleotide-releasing factor 1 | 8674 | -0.026 | -0.4087 | No |
| 59 | SENP3 | SENP3 Entrez, Source | SUMO1/sentrin/SMT3 specific peptidase 3 | 8784 | -0.028 | -0.4141 | No |
| 60 | NSF | NSF Entrez, Source | N-ethylmaleimide-sensitive factor | 8958 | -0.031 | -0.4240 | No |
| 61 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 9287 | -0.038 | -0.4450 | No |
| 62 | RHOG | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 9303 | -0.038 | -0.4423 | No |
| 63 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 9531 | -0.042 | -0.4552 | No |
| 64 | HPCA | HPCA Entrez, Source | hippocalcin | 9596 | -0.043 | -0.4557 | No |
| 65 | TMOD2 | TMOD2 Entrez, Source | tropomodulin 2 (neuronal) | 9605 | -0.044 | -0.4519 | No |
| 66 | TPP2 | TPP2 Entrez, Source | tripeptidyl peptidase II | 9613 | -0.044 | -0.4480 | No |
| 67 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 9778 | -0.047 | -0.4557 | No |
| 68 | SUMO2 | SUMO2 Entrez, Source | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 9828 | -0.048 | -0.4545 | No |
| 69 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9930 | -0.051 | -0.4570 | No |
| 70 | WNT11 | WNT11 Entrez, Source | wingless-type MMTV integration site family, member 11 | 10113 | -0.055 | -0.4653 | No |
| 71 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 10118 | -0.055 | -0.4601 | No |
| 72 | XYLT2 | XYLT2 Entrez, Source | xylosyltransferase II | 10280 | -0.059 | -0.4663 | No |
| 73 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 10358 | -0.060 | -0.4661 | No |
| 74 | USP48 | USP48 Entrez, Source | ubiquitin specific peptidase 48 | 10490 | -0.064 | -0.4695 | No |
| 75 | CALM1 | CALM1 Entrez, Source | calmodulin 1 (phosphorylase kinase, delta) | 10814 | -0.073 | -0.4866 | No |
| 76 | CDC42BPB | CDC42BPB Entrez, Source | CDC42 binding protein kinase beta (DMPK-like) | 10847 | -0.074 | -0.4816 | No |
| 77 | POU3F1 | POU3F1 Entrez, Source | POU domain, class 3, transcription factor 1 | 11131 | -0.083 | -0.4947 | No |
| 78 | MPZL1 | MPZL1 Entrez, Source | myelin protein zero-like 1 | 11172 | -0.085 | -0.4892 | No |
| 79 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 11219 | -0.087 | -0.4840 | No |
| 80 | SPRED1 | SPRED1 Entrez, Source | sprouty-related, EVH1 domain containing 1 | 11241 | -0.088 | -0.4767 | No |
| 81 | PHC2 | PHC2 Entrez, Source | polyhomeotic homolog 2 (Drosophila) | 11283 | -0.090 | -0.4708 | No |
| 82 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 11790 | -0.113 | -0.4977 | No |
| 83 | MAX | MAX Entrez, Source | MYC associated factor X | 11963 | -0.122 | -0.4984 | Yes |
| 84 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 12099 | -0.132 | -0.4953 | Yes |
| 85 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 12198 | -0.139 | -0.4887 | Yes |
| 86 | HS2ST1 | HS2ST1 Entrez, Source | heparan sulfate 2-O-sulfotransferase 1 | 12206 | -0.140 | -0.4752 | Yes |
| 87 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 12319 | -0.150 | -0.4686 | Yes |
| 88 | ILK | ILK Entrez, Source | integrin-linked kinase | 12453 | -0.164 | -0.4621 | Yes |
| 89 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 12528 | -0.175 | -0.4501 | Yes |
| 90 | JUB | JUB Entrez, Source | jub, ajuba homolog (Xenopus laevis) | 12625 | -0.189 | -0.4383 | Yes |
| 91 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 12640 | -0.193 | -0.4200 | Yes |
| 92 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 12812 | -0.228 | -0.4100 | Yes |
| 93 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12815 | -0.228 | -0.3872 | Yes |
| 94 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12826 | -0.231 | -0.3647 | Yes |
| 95 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 12828 | -0.232 | -0.3415 | Yes |
| 96 | GPRC5C | GPRC5C Entrez, Source | G protein-coupled receptor, family C, group 5, member C | 12872 | -0.243 | -0.3203 | Yes |
| 97 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.3009 | Yes |
| 98 | HOMER3 | HOMER3 Entrez, Source | homer homolog 3 (Drosophila) | 13031 | -0.307 | -0.2715 | Yes |
| 99 | DDAH1 | DDAH1 Entrez, Source | dimethylarginine dimethylaminohydrolase 1 | 13118 | -0.367 | -0.2410 | Yes |
| 100 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13187 | -0.451 | -0.2008 | Yes |
| 101 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13280 | -0.659 | -0.1415 | Yes |
| 102 | ADM | ADM Entrez, Source | adrenomedullin | 13287 | -0.697 | -0.0718 | Yes |
| 103 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | 0.0030 | Yes |
