Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | VANTVEER_BREAST_OUTCOME_GOOD_VS_POOR_DN |
| Enrichment Score (ES) | -0.6219716 |
| Normalized Enrichment Score (NES) | -1.844172 |
| Nominal p-value | 0.003508772 |
| FDR q-value | 0.028054517 |
| FWER p-Value | 0.842 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MCCC1 | MCCC1 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 556 | 0.192 | -0.0057 | No |
| 2 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 608 | 0.185 | 0.0253 | No |
| 3 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 901 | 0.153 | 0.0321 | No |
| 4 | TMEFF1 | TMEFF1 Entrez, Source | transmembrane protein with EGF-like and two follistatin-like domains 1 | 1224 | 0.128 | 0.0320 | No |
| 5 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 1308 | 0.124 | 0.0491 | No |
| 6 | ESM1 | ESM1 Entrez, Source | endothelial cell-specific molecule 1 | 2274 | 0.086 | -0.0073 | No |
| 7 | CP | CP Entrez, Source | ceruloplasmin (ferroxidase) | 3349 | 0.059 | -0.0769 | No |
| 8 | MGAT4A | MGAT4A Entrez, Source | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 3423 | 0.058 | -0.0715 | No |
| 9 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 3595 | 0.054 | -0.0743 | No |
| 10 | NMU | NMU Entrez, Source | neuromedin U | 3853 | 0.049 | -0.0843 | No |
| 11 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 3861 | 0.049 | -0.0757 | No |
| 12 | STX1A | STX1A Entrez, Source | syntaxin 1A (brain) | 3958 | 0.047 | -0.0740 | No |
| 13 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4057 | 0.045 | -0.0728 | No |
| 14 | ST7 | ST7 Entrez, Source | suppression of tumorigenicity 7 | 4100 | 0.045 | -0.0676 | No |
| 15 | ASNS | ASNS Entrez, Source | asparagine synthetase | 4245 | 0.042 | -0.0705 | No |
| 16 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 4260 | 0.042 | -0.0636 | No |
| 17 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 5119 | 0.027 | -0.1230 | No |
| 18 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | -0.2617 | No |
| 19 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 7152 | -0.002 | -0.2751 | No |
| 20 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 7411 | -0.006 | -0.2933 | No |
| 21 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 7605 | -0.009 | -0.3061 | No |
| 22 | PTDSS1 | PTDSS1 Entrez, Source | phosphatidylserine synthase 1 | 7804 | -0.012 | -0.3187 | No |
| 23 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 7875 | -0.013 | -0.3215 | No |
| 24 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8545 | -0.024 | -0.3673 | No |
| 25 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 8584 | -0.024 | -0.3656 | No |
| 26 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 9831 | -0.048 | -0.4501 | No |
| 27 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 11568 | -0.103 | -0.5612 | No |
| 28 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 12377 | -0.156 | -0.5927 | Yes |
| 29 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12437 | -0.162 | -0.5666 | Yes |
| 30 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 12656 | -0.196 | -0.5461 | Yes |
| 31 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12851 | -0.238 | -0.5159 | Yes |
| 32 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12949 | -0.272 | -0.4719 | Yes |
| 33 | AKAP2 | AKAP2 Entrez, Source | A kinase (PRKA) anchor protein 2 | 13107 | -0.362 | -0.4156 | Yes |
| 34 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13129 | -0.381 | -0.3454 | Yes |
| 35 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13266 | -0.607 | -0.2413 | Yes |
| 36 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.1257 | Yes |
| 37 | ADM | ADM Entrez, Source | adrenomedullin | 13287 | -0.697 | 0.0041 | Yes |
