Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | AGED_MOUSE_CEREBELLUM_DN |
| Enrichment Score (ES) | 0.6157486 |
| Normalized Enrichment Score (NES) | 1.791981 |
| Nominal p-value | 0.0035650623 |
| FDR q-value | 0.030411063 |
| FWER p-Value | 0.952 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 60 | 0.762 | 0.1538 | Yes |
| 2 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 158 | 0.552 | 0.2611 | Yes |
| 3 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 347 | 0.366 | 0.3231 | Yes |
| 4 | HSPA4 | HSPA4 Entrez, Source | heat shock 70kDa protein 4 | 361 | 0.358 | 0.3965 | Yes |
| 5 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 391 | 0.341 | 0.4652 | Yes |
| 6 | CNP | CNP Entrez, Source | 2',3'-cyclic nucleotide 3' phosphodiesterase | 706 | 0.233 | 0.4900 | Yes |
| 7 | PTPRD | PTPRD Entrez, Source | protein tyrosine phosphatase, receptor type, D | 731 | 0.229 | 0.5358 | Yes |
| 8 | MERTK | MERTK Entrez, Source | c-mer proto-oncogene tyrosine kinase | 1000 | 0.183 | 0.5536 | Yes |
| 9 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 1062 | 0.175 | 0.5853 | Yes |
| 10 | CD4 | CD4 Entrez, Source | CD4 molecule | 1315 | 0.149 | 0.5974 | Yes |
| 11 | SNCA | SNCA Entrez, Source | synuclein, alpha (non A4 component of amyloid precursor) | 1455 | 0.139 | 0.6157 | Yes |
| 12 | NAB2 | NAB2 Entrez, Source | NGFI-A binding protein 2 (EGR1 binding protein 2) | 2416 | 0.091 | 0.5625 | No |
| 13 | HGFAC | HGFAC Entrez, Source | HGF activator | 3198 | 0.066 | 0.5175 | No |
| 14 | CLIC3 | CLIC3 Entrez, Source | chloride intracellular channel 3 | 4055 | 0.043 | 0.4622 | No |
| 15 | CSF2 | CSF2 Entrez, Source | colony stimulating factor 2 (granulocyte-macrophage) | 4451 | 0.035 | 0.4398 | No |
| 16 | SLC4A1 | SLC4A1 Entrez, Source | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 4796 | 0.028 | 0.4197 | No |
| 17 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 4947 | 0.025 | 0.4137 | No |
| 18 | NPY1R | NPY1R Entrez, Source | neuropeptide Y receptor Y1 | 5663 | 0.012 | 0.3624 | No |
| 19 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 6136 | 0.003 | 0.3275 | No |
| 20 | LIN7B | LIN7B Entrez, Source | lin-7 homolog B (C. elegans) | 7534 | -0.022 | 0.2272 | No |
| 21 | CAMK2G | CAMK2G Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma | 7620 | -0.024 | 0.2258 | No |
| 22 | DOC2B | DOC2B Entrez, Source | double C2-like domains, beta | 7728 | -0.026 | 0.2231 | No |
| 23 | SMARCA4 | SMARCA4 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 8251 | -0.036 | 0.1914 | No |
| 24 | CACNG1 | CACNG1 Entrez, Source | calcium channel, voltage-dependent, gamma subunit 1 | 8508 | -0.042 | 0.1809 | No |
| 25 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 10664 | -0.096 | 0.0389 | No |
| 26 | TCEA2 | TCEA2 Entrez, Source | transcription elongation factor A (SII), 2 | 10733 | -0.098 | 0.0542 | No |
| 27 | ANXA7 | ANXA7 Entrez, Source | annexin A7 | 10981 | -0.108 | 0.0580 | No |
| 28 | GALK1 | GALK1 Entrez, Source | galactokinase 1 | 11136 | -0.114 | 0.0700 | No |
| 29 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 11388 | -0.124 | 0.0769 | No |
| 30 | FRAP1 | FRAP1 Entrez, Source | FK506 binding protein 12-rapamycin associated protein 1 | 11920 | -0.151 | 0.0685 | No |
| 31 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 12353 | -0.184 | 0.0743 | No |
