Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | AROMATIC_COMPOUND_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.7277755 |
| Normalized Enrichment Score (NES) | 1.8504773 |
| Nominal p-value | 0.0019230769 |
| FDR q-value | 0.01897377 |
| FWER p-Value | 0.768 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 46 | 0.834 | 0.1958 | Yes |
| 2 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 138 | 0.591 | 0.3302 | Yes |
| 3 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 232 | 0.457 | 0.4323 | Yes |
| 4 | SULT1B1 | SULT1B1 Entrez, Source | sulfotransferase family, cytosolic, 1B, member 1 | 238 | 0.454 | 0.5403 | Yes |
| 5 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.6318 | Yes |
| 6 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 595 | 0.258 | 0.6713 | Yes |
| 7 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.6934 | Yes |
| 8 | MOCS2 | MOCS2 Entrez, Source | molybdenum cofactor synthesis 2 | 1028 | 0.179 | 0.7278 | Yes |
| 9 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 1478 | 0.137 | 0.7267 | No |
| 10 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 5998 | 0.005 | 0.3888 | No |
| 11 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 6481 | -0.003 | 0.3534 | No |
| 12 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 7441 | -0.021 | 0.2864 | No |
| 13 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 9384 | -0.060 | 0.1550 | No |
| 14 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 9602 | -0.065 | 0.1543 | No |
| 15 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 10558 | -0.092 | 0.1045 | No |
| 16 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 11250 | -0.118 | 0.0809 | No |
| 17 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 11646 | -0.136 | 0.0836 | No |
| 18 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | 0.0753 | No |
