Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | BETA_ALANINE_METABOLISM |
| Enrichment Score (ES) | 0.6795725 |
| Normalized Enrichment Score (NES) | 1.8479913 |
| Nominal p-value | 0.0019230769 |
| FDR q-value | 0.019101465 |
| FWER p-Value | 0.779 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 112 | 0.632 | 0.1221 | Yes |
| 2 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 185 | 0.510 | 0.2221 | Yes |
| 3 | UPB1 | UPB1 Entrez, Source | ureidopropionase, beta | 265 | 0.427 | 0.3044 | Yes |
| 4 | DPYS | DPYS Entrez, Source | dihydropyrimidinase | 287 | 0.410 | 0.3876 | Yes |
| 5 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 346 | 0.367 | 0.4591 | Yes |
| 6 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 375 | 0.349 | 0.5291 | Yes |
| 7 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 526 | 0.277 | 0.5750 | Yes |
| 8 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 817 | 0.210 | 0.5966 | Yes |
| 9 | SDS | SDS Entrez, Source | serine dehydratase | 1007 | 0.182 | 0.6200 | Yes |
| 10 | CNDP1 | CNDP1 Entrez, Source | carnosine dipeptidase 1 (metallopeptidase M20 family) | 1188 | 0.162 | 0.6399 | Yes |
| 11 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 1428 | 0.140 | 0.6510 | Yes |
| 12 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 1715 | 0.122 | 0.6547 | Yes |
| 13 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 1720 | 0.122 | 0.6796 | Yes |
| 14 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 2173 | 0.101 | 0.6664 | No |
| 15 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 2398 | 0.092 | 0.6686 | No |
| 16 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 2544 | 0.086 | 0.6754 | No |
| 17 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 2893 | 0.074 | 0.6647 | No |
| 18 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 3710 | 0.052 | 0.6141 | No |
| 19 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 3774 | 0.051 | 0.6198 | No |
| 20 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 3794 | 0.050 | 0.6288 | No |
| 21 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 4375 | 0.036 | 0.5927 | No |
| 22 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 5594 | 0.013 | 0.5039 | No |
| 23 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 9270 | -0.057 | 0.2398 | No |
| 24 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 11204 | -0.116 | 0.1187 | No |
| 25 | SMS | SMS Entrez, Source | spermine synthase | 12527 | -0.202 | 0.0612 | No |
