Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | BLEO_MOUSE_LYMPH_HIGH_24HRS_DN |
| Enrichment Score (ES) | -0.5982419 |
| Normalized Enrichment Score (NES) | -1.7707899 |
| Nominal p-value | 0.012578616 |
| FDR q-value | 0.059840202 |
| FWER p-Value | 0.947 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IDH3A | IDH3A Entrez, Source | isocitrate dehydrogenase 3 (NAD+) alpha | 843 | 0.206 | 0.0067 | No |
| 2 | PSMD1 | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 3336 | 0.062 | -0.1595 | No |
| 3 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 3472 | 0.058 | -0.1498 | No |
| 4 | MARK2 | MARK2 Entrez, Source | MAP/microtubule affinity-regulating kinase 2 | 4871 | 0.027 | -0.2457 | No |
| 5 | PPP2CB | PPP2CB Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform | 5055 | 0.023 | -0.2516 | No |
| 6 | SEC61A1 | SEC61A1 Entrez, Source | Sec61 alpha 1 subunit (S. cerevisiae) | 6253 | 0.001 | -0.3413 | No |
| 7 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 6295 | -0.000 | -0.3444 | No |
| 8 | POLR2C | POLR2C Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 7347 | -0.019 | -0.4170 | No |
| 9 | PPM1G | PPM1G Entrez, Source | protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform | 8259 | -0.037 | -0.4729 | No |
| 10 | FKBP1A | FKBP1A Entrez, Source | FK506 binding protein 1A, 12kDa | 8597 | -0.043 | -0.4835 | No |
| 11 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 9390 | -0.060 | -0.5225 | No |
| 12 | RDX | RDX Entrez, Source | radixin | 10400 | -0.087 | -0.5685 | Yes |
| 13 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10524 | -0.091 | -0.5469 | Yes |
| 14 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10578 | -0.093 | -0.5194 | Yes |
| 15 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 10898 | -0.105 | -0.5077 | Yes |
| 16 | C1QBP | C1QBP Entrez, Source | complement component 1, q subcomponent binding protein | 10931 | -0.106 | -0.4741 | Yes |
| 17 | BCAP29 | BCAP29 Entrez, Source | B-cell receptor-associated protein 29 | 11156 | -0.115 | -0.4519 | Yes |
| 18 | RAB14 | RAB14 Entrez, Source | RAB14, member RAS oncogene family | 11280 | -0.119 | -0.4205 | Yes |
| 19 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 11364 | -0.123 | -0.3849 | Yes |
| 20 | HNRPC | HNRPC Entrez, Source | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 11772 | -0.143 | -0.3669 | Yes |
| 21 | ANP32B | ANP32B Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 12233 | -0.174 | -0.3422 | Yes |
| 22 | PRMT1 | PRMT1 Entrez, Source | protein arginine methyltransferase 1 | 12302 | -0.180 | -0.2862 | Yes |
| 23 | FBL | FBL Entrez, Source | fibrillarin | 12456 | -0.194 | -0.2318 | Yes |
| 24 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 12468 | -0.195 | -0.1662 | Yes |
| 25 | GCS1 | GCS1 Entrez, Source | - | 12516 | -0.201 | -0.1015 | Yes |
| 26 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.0367 | Yes |
| 27 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 12901 | -0.267 | 0.0331 | Yes |
