Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | BRCA_BRCA1_NEG |
| Enrichment Score (ES) | 0.54003775 |
| Normalized Enrichment Score (NES) | 1.8703095 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.016775306 |
| FWER p-Value | 0.686 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 11 | 1.276 | 0.1038 | Yes |
| 2 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 43 | 0.843 | 0.1706 | Yes |
| 3 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 97 | 0.667 | 0.2213 | Yes |
| 4 | BEXL1 | BEXL1 Entrez, Source | brain expressed X-linked-like 1 | 135 | 0.595 | 0.2673 | Yes |
| 5 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 164 | 0.541 | 0.3096 | Yes |
| 6 | HMGCS2 | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 173 | 0.525 | 0.3521 | Yes |
| 7 | DCI | DCI Entrez, Source | dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase) | 302 | 0.399 | 0.3752 | Yes |
| 8 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 316 | 0.387 | 0.4059 | Yes |
| 9 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 321 | 0.383 | 0.4370 | Yes |
| 10 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 480 | 0.292 | 0.4490 | Yes |
| 11 | GPC4 | GPC4 Entrez, Source | glypican 4 | 577 | 0.262 | 0.4633 | Yes |
| 12 | STXBP1 | STXBP1 Entrez, Source | syntaxin binding protein 1 | 862 | 0.201 | 0.4584 | Yes |
| 13 | KLF9 | KLF9 Entrez, Source | Kruppel-like factor 9 | 905 | 0.195 | 0.4712 | Yes |
| 14 | STARD10 | STARD10 Entrez, Source | START domain containing 10 | 953 | 0.188 | 0.4831 | Yes |
| 15 | HDGFRP3 | HDGFRP3 Entrez, Source | - | 1011 | 0.181 | 0.4936 | Yes |
| 16 | TSPAN8 | TSPAN8 Entrez, Source | tetraspanin 8 | 1016 | 0.180 | 0.5081 | Yes |
| 17 | TFPI | TFPI Entrez, Source | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 1052 | 0.177 | 0.5200 | Yes |
| 18 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 1195 | 0.161 | 0.5225 | Yes |
| 19 | RETSAT | RETSAT Entrez, Source | retinol saturase (all-trans-retinol 13,14-reductase) | 1210 | 0.160 | 0.5346 | Yes |
| 20 | INPP4B | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 1302 | 0.150 | 0.5400 | Yes |
| 21 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 1556 | 0.131 | 0.5317 | No |
| 22 | ENC1 | ENC1 Entrez, Source | ectodermal-neural cortex (with BTB-like domain) | 1856 | 0.114 | 0.5185 | No |
| 23 | CRYM | CRYM Entrez, Source | crystallin, mu | 1874 | 0.113 | 0.5265 | No |
| 24 | SLC40A1 | SLC40A1 Entrez, Source | solute carrier family 40 (iron-regulated transporter), member 1 | 2036 | 0.106 | 0.5230 | No |
| 25 | GOSR1 | GOSR1 Entrez, Source | golgi SNAP receptor complex member 1 | 2055 | 0.105 | 0.5303 | No |
| 26 | PALMD | PALMD Entrez, Source | palmdelphin | 2123 | 0.103 | 0.5336 | No |
| 27 | STK39 | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 2151 | 0.101 | 0.5399 | No |
| 28 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 2353 | 0.093 | 0.5324 | No |
| 29 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2361 | 0.093 | 0.5395 | No |
| 30 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 2490 | 0.088 | 0.5371 | No |
| 31 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 2894 | 0.074 | 0.5127 | No |
| 32 | DUSP4 | DUSP4 Entrez, Source | dual specificity phosphatase 4 | 2916 | 0.074 | 0.5172 | No |
| 33 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 2946 | 0.073 | 0.5210 | No |
| 34 | NPTN | NPTN Entrez, Source | neuroplastin | 3133 | 0.068 | 0.5125 | No |
| 35 | SH3BP4 | SH3BP4 Entrez, Source | SH3-domain binding protein 4 | 3232 | 0.065 | 0.5104 | No |
| 36 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 3489 | 0.058 | 0.4958 | No |
| 37 | CTSF | CTSF Entrez, Source | cathepsin F | 3540 | 0.056 | 0.4966 | No |
| 38 | HAGH | HAGH Entrez, Source | hydroxyacylglutathione hydrolase | 3639 | 0.054 | 0.4937 | No |
| 39 | PDLIM3 | PDLIM3 Entrez, Source | PDZ and LIM domain 3 | 3680 | 0.053 | 0.4950 | No |
| 40 | GALNT7 | GALNT7 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) | 3717 | 0.052 | 0.4965 | No |
| 41 | SPON1 | SPON1 Entrez, Source | spondin 1, extracellular matrix protein | 3726 | 0.052 | 0.5001 | No |
| 42 | GREM1 | GREM1 Entrez, Source | gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) | 3749 | 0.051 | 0.5027 | No |
| 43 | GPC1 | GPC1 Entrez, Source | glypican 1 | 3928 | 0.046 | 0.4930 | No |
| 44 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 3983 | 0.045 | 0.4926 | No |
| 45 | RAB3B | RAB3B Entrez, Source | RAB3B, member RAS oncogene family | 3994 | 0.045 | 0.4955 | No |
| 46 | CPE | CPE Entrez, Source | carboxypeptidase E | 4222 | 0.039 | 0.4816 | No |
| 47 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 4357 | 0.037 | 0.4745 | No |
| 48 | PIB5PA | PIB5PA Entrez, Source | phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | 4628 | 0.031 | 0.4567 | No |
| 49 | SC5DL | SC5DL Entrez, Source | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like | 4644 | 0.031 | 0.4581 | No |
| 50 | TMEM98 | TMEM98 Entrez, Source | transmembrane protein 98 | 4855 | 0.027 | 0.4445 | No |
| 51 | ETFB | ETFB Entrez, Source | electron-transfer-flavoprotein, beta polypeptide | 4956 | 0.025 | 0.4390 | No |
| 52 | COL23A1 | COL23A1 Entrez, Source | collagen, type XXIII, alpha 1 | 5329 | 0.018 | 0.4124 | No |
| 53 | MID1IP1 | MID1IP1 Entrez, Source | MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish)) | 5440 | 0.016 | 0.4054 | No |
| 54 | SLC9A2 | SLC9A2 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 2 | 5583 | 0.013 | 0.3958 | No |
| 55 | PLA2G10 | PLA2G10 Entrez, Source | phospholipase A2, group X | 5609 | 0.013 | 0.3949 | No |
| 56 | WT1 | WT1 Entrez, Source | Wilms tumor 1 | 5809 | 0.009 | 0.3806 | No |
| 57 | CAMK2N1 | CAMK2N1 Entrez, Source | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 5852 | 0.008 | 0.3781 | No |
| 58 | SCAMP1 | SCAMP1 Entrez, Source | secretory carrier membrane protein 1 | 6004 | 0.005 | 0.3671 | No |
| 59 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 6151 | 0.002 | 0.3563 | No |
| 60 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 6163 | 0.002 | 0.3556 | No |
| 61 | PNMT | PNMT Entrez, Source | phenylethanolamine N-methyltransferase | 6269 | 0.000 | 0.3477 | No |
| 62 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 6351 | -0.001 | 0.3417 | No |
| 63 | EMP2 | EMP2 Entrez, Source | epithelial membrane protein 2 | 6473 | -0.003 | 0.3328 | No |
| 64 | FMOD | FMOD Entrez, Source | fibromodulin | 6665 | -0.007 | 0.3189 | No |
| 65 | CHGA | CHGA Entrez, Source | chromogranin A (parathyroid secretory protein 1) | 6669 | -0.007 | 0.3192 | No |
| 66 | DNAJA4 | DNAJA4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 4 | 7050 | -0.013 | 0.2917 | No |
| 67 | CLEC11A | CLEC11A Entrez, Source | C-type lectin domain family 11, member A | 7186 | -0.016 | 0.2827 | No |
| 68 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 7282 | -0.018 | 0.2770 | No |
| 69 | UNC119 | UNC119 Entrez, Source | unc-119 homolog (C. elegans) | 7443 | -0.021 | 0.2666 | No |
| 70 | CDC42BPA | CDC42BPA Entrez, Source | CDC42 binding protein kinase alpha (DMPK-like) | 8008 | -0.031 | 0.2266 | No |
| 71 | NEO1 | NEO1 Entrez, Source | neogenin homolog 1 (chicken) | 8561 | -0.043 | 0.1885 | No |
| 72 | PARVA | PARVA Entrez, Source | parvin, alpha | 8673 | -0.045 | 0.1838 | No |
| 73 | GPRC5C | GPRC5C Entrez, Source | G protein-coupled receptor, family C, group 5, member C | 8812 | -0.048 | 0.1773 | No |
| 74 | GLI3 | GLI3 Entrez, Source | GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) | 8942 | -0.051 | 0.1717 | No |
| 75 | TEGT | TEGT Entrez, Source | testis enhanced gene transcript (BAX inhibitor 1) | 9169 | -0.055 | 0.1592 | No |
| 76 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 9332 | -0.059 | 0.1518 | No |
| 77 | TXNDC13 | TXNDC13 Entrez, Source | thioredoxin domain containing 13 | 9567 | -0.065 | 0.1394 | No |
| 78 | PDE8B | PDE8B Entrez, Source | phosphodiesterase 8B | 9690 | -0.068 | 0.1357 | No |
| 79 | HTRA1 | HTRA1 Entrez, Source | HtrA serine peptidase 1 | 9698 | -0.068 | 0.1408 | No |
| 80 | TSPYL4 | TSPYL4 Entrez, Source | TSPY-like 4 | 9720 | -0.069 | 0.1448 | No |
| 81 | HEY1 | HEY1 Entrez, Source | hairy/enhancer-of-split related with YRPW motif 1 | 9928 | -0.075 | 0.1353 | No |
| 82 | SYNJ2BP | SYNJ2BP Entrez, Source | synaptojanin 2 binding protein | 10138 | -0.080 | 0.1261 | No |
| 83 | DUSP13 | DUSP13 Entrez, Source | dual specificity phosphatase 13 | 10198 | -0.082 | 0.1283 | No |
| 84 | LRRC17 | LRRC17 Entrez, Source | leucine rich repeat containing 17 | 10475 | -0.090 | 0.1148 | No |
| 85 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 10759 | -0.099 | 0.1016 | No |
| 86 | SORD | SORD Entrez, Source | sorbitol dehydrogenase | 11093 | -0.112 | 0.0856 | No |
| 87 | PRKD1 | PRKD1 Entrez, Source | protein kinase D1 | 11159 | -0.115 | 0.0901 | No |
| 88 | MPDZ | MPDZ Entrez, Source | multiple PDZ domain protein | 11344 | -0.122 | 0.0863 | No |
| 89 | CSNK1A1 | CSNK1A1 Entrez, Source | casein kinase 1, alpha 1 | 11439 | -0.127 | 0.0896 | No |
| 90 | TAOK1 | TAOK1 Entrez, Source | TAO kinase 1 | 11735 | -0.140 | 0.0788 | No |
| 91 | BRD8 | BRD8 Entrez, Source | bromodomain containing 8 | 12049 | -0.161 | 0.0683 | No |
| 92 | BMPR2 | BMPR2 Entrez, Source | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 12122 | -0.166 | 0.0765 | No |
| 93 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 12410 | -0.189 | 0.0703 | No |
