Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | BRCA_PROGNOSIS_NEG |
| Enrichment Score (ES) | -0.520242 |
| Normalized Enrichment Score (NES) | -1.6730826 |
| Nominal p-value | 0.004484305 |
| FDR q-value | 0.10803349 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 401 | 0.337 | 0.0342 | No |
| 2 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 835 | 0.207 | 0.0412 | No |
| 3 | MCCC1 | MCCC1 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 2454 | 0.090 | -0.0633 | No |
| 4 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 2756 | 0.078 | -0.0710 | No |
| 5 | NMU | NMU Entrez, Source | neuromedin U | 3179 | 0.066 | -0.0901 | No |
| 6 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 3581 | 0.055 | -0.1096 | No |
| 7 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 3758 | 0.051 | -0.1131 | No |
| 8 | ESM1 | ESM1 Entrez, Source | endothelial cell-specific molecule 1 | 4360 | 0.037 | -0.1513 | No |
| 9 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 4556 | 0.033 | -0.1597 | No |
| 10 | ASNS | ASNS Entrez, Source | asparagine synthetase | 5217 | 0.020 | -0.2055 | No |
| 11 | MGAT4A | MGAT4A Entrez, Source | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 5923 | 0.007 | -0.2572 | No |
| 12 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 6450 | -0.003 | -0.2963 | No |
| 13 | SPBC25 | SPBC25 Entrez, Source | spindle pole body component 25 homolog (S. cerevisiae) | 6642 | -0.006 | -0.3094 | No |
| 14 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 6801 | -0.009 | -0.3196 | No |
| 15 | MRPL13 | MRPL13 Entrez, Source | mitochondrial ribosomal protein L13 | 6839 | -0.009 | -0.3206 | No |
| 16 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 7190 | -0.016 | -0.3439 | No |
| 17 | CDC42BPA | CDC42BPA Entrez, Source | CDC42 binding protein kinase alpha (DMPK-like) | 8008 | -0.031 | -0.3993 | No |
| 18 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 8537 | -0.042 | -0.4310 | No |
| 19 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 8722 | -0.046 | -0.4360 | No |
| 20 | MTDH | MTDH Entrez, Source | metadherin | 9163 | -0.055 | -0.4586 | No |
| 21 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 9855 | -0.073 | -0.4967 | No |
| 22 | UCHL5 | UCHL5 Entrez, Source | ubiquitin carboxyl-terminal hydrolase L5 | 10092 | -0.079 | -0.4993 | No |
| 23 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 10239 | -0.083 | -0.4945 | No |
| 24 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 10293 | -0.084 | -0.4824 | No |
| 25 | PTDSS1 | PTDSS1 Entrez, Source | phosphatidylserine synthase 1 | 10797 | -0.101 | -0.5009 | Yes |
| 26 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 10956 | -0.107 | -0.4924 | Yes |
| 27 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 10987 | -0.108 | -0.4741 | Yes |
| 28 | ADM | ADM Entrez, Source | adrenomedullin | 11063 | -0.110 | -0.4586 | Yes |
| 29 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 11249 | -0.118 | -0.4499 | Yes |
| 30 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 11250 | -0.118 | -0.4274 | Yes |
| 31 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12163 | -0.169 | -0.4637 | Yes |
| 32 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 12194 | -0.171 | -0.4333 | Yes |
| 33 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 12221 | -0.173 | -0.4022 | Yes |
| 34 | AURKA | AURKA Entrez, Source | aurora kinase A | 12238 | -0.175 | -0.3701 | Yes |
| 35 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.3370 | Yes |
| 36 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12617 | -0.213 | -0.3242 | Yes |
| 37 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.2911 | Yes |
| 38 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 12796 | -0.240 | -0.2460 | Yes |
| 39 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13222 | -0.428 | -0.1962 | Yes |
| 40 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13268 | -0.519 | -0.1003 | Yes |
| 41 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | 0.0041 | Yes |
