Details for gene set CALCIUM_REGULATION_IN_CARDIAC

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in class	double_gel_8d
GeneSet	CALCIUM_REGULATION_IN_CARDIAC_CELLS
Enrichment Score (ES)	0.5662463
Normalized Enrichment Score (NES)	2.0508406
Nominal p-value	0.0
FDR q-value	0.0028363036
FWER p-Value	0.058

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RGS2	RGS2 Entrez, Source	regulator of G-protein signalling 2, 24kDa	50	0.810	0.0534	Yes
2	RGS1	RGS1 Entrez, Source	regulator of G-protein signalling 1	73	0.715	0.1022	Yes
3	RGS5	RGS5 Entrez, Source	regulator of G-protein signalling 5	125	0.616	0.1419	Yes
4	GJB5	GJB5 Entrez, Source	gap junction protein, beta 5 (connexin 31.1)	171	0.530	0.1759	Yes
5	GRK5	GRK5 Entrez, Source	G protein-coupled receptor kinase 5	188	0.507	0.2105	Yes
6	RGS16	RGS16 Entrez, Source	regulator of G-protein signalling 16	205	0.482	0.2434	Yes
7	GJB3	GJB3 Entrez, Source	gap junction protein, beta 3, 31kDa (connexin 31)	210	0.476	0.2767	Yes
8	PRKAR2B	PRKAR2B Entrez, Source	protein kinase, cAMP-dependent, regulatory, type II, beta	214	0.474	0.3100	Yes
9	RGS10	RGS10 Entrez, Source	regulator of G-protein signalling 10	247	0.443	0.3388	Yes
10	ITPR1	ITPR1 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 1	282	0.413	0.3654	Yes
11	RGS3	RGS3 Entrez, Source	regulator of G-protein signalling 3	301	0.402	0.3925	Yes
12	GJA1	GJA1 Entrez, Source	gap junction protein, alpha 1, 43kDa (connexin 43)	316	0.387	0.4187	Yes
13	PKIA	PKIA Entrez, Source	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	588	0.260	0.4166	Yes
14	PKIB	PKIB Entrez, Source	protein kinase (cAMP-dependent, catalytic) inhibitor beta	592	0.258	0.4346	Yes
15	GJB2	GJB2 Entrez, Source	gap junction protein, beta 2, 26kDa (connexin 26)	628	0.250	0.4496	Yes
16	RGS4	RGS4 Entrez, Source	regulator of G-protein signalling 4	639	0.247	0.4662	Yes
17	GJB1	GJB1 Entrez, Source	gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)	690	0.237	0.4792	Yes
18	FXYD2	FXYD2 Entrez, Source	FXYD domain containing ion transport regulator 2	960	0.187	0.4721	Yes
19	ATP1B1	ATP1B1 Entrez, Source	ATPase, Na+/K+ transporting, beta 1 polypeptide	973	0.186	0.4843	Yes
20	ADRB2	ADRB2 Entrez, Source	adrenergic, beta-2-, receptor, surface	987	0.184	0.4963	Yes
21	PLN	PLN Entrez, Source	phospholamban	994	0.183	0.5088	Yes
22	PRKAR1B	PRKAR1B Entrez, Source	protein kinase, cAMP-dependent, regulatory, type I, beta	1117	0.169	0.5115	Yes
23	PKIG	PKIG Entrez, Source	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	1121	0.169	0.5232	Yes
24	PRKCA	PRKCA Entrez, Source	protein kinase C, alpha	1423	0.141	0.5104	Yes
25	YWHAQ	YWHAQ Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	1447	0.139	0.5184	Yes
26	ADCY5	ADCY5 Entrez, Source	adenylate cyclase 5	1541	0.132	0.5207	Yes
27	ADRA1D	ADRA1D Entrez, Source	adrenergic, alpha-1D-, receptor	1559	0.131	0.5287	Yes
28	GNAI2	GNAI2 Entrez, Source	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	1585	0.129	0.5359	Yes
29	ADCY6	ADCY6 Entrez, Source	adenylate cyclase 6	1649	0.125	0.5400	Yes
30	ANXA6	ANXA6 Entrez, Source	annexin A6	1714	0.122	0.5437	Yes
31	GNAQ	GNAQ Entrez, Source	guanine nucleotide binding protein (G protein), q polypeptide	1722	0.122	0.5518	Yes
32	ATP2A3	ATP2A3 Entrez, Source	ATPase, Ca++ transporting, ubiquitous	1837	0.115	0.5513	Yes
33	CACNA1E	CACNA1E Entrez, Source	calcium channel, voltage-dependent, alpha 1E subunit	1843	0.115	0.5590	Yes
34	ATP1A4	ATP1A4 Entrez, Source	ATPase, Na+/K+ transporting, alpha 4 polypeptide	1959	0.109	0.5580	Yes
35	CALM3	CALM3 Entrez, Source	calmodulin 3 (phosphorylase kinase, delta)	1983	0.109	0.5639	Yes
36	ADRB3	ADRB3 Entrez, Source	adrenergic, beta-3-, receptor	2147	0.102	0.5588	Yes
37	ARRB1	ARRB1 Entrez, Source	arrestin, beta 1	2228	0.098	0.5597	Yes
38	RGS7	RGS7 Entrez, Source	regulator of G-protein signalling 7	2271	0.097	0.5633	Yes
39	GNB5	GNB5 Entrez, Source	guanine nucleotide binding protein (G protein), beta 5	2462	0.089	0.5552	Yes
40	PEA15	PEA15 Entrez, Source	phosphoprotein enriched in astrocytes 15	2496	0.088	0.5590	Yes
41	PRKCH	PRKCH Entrez, Source	protein kinase C, eta	2545	0.086	0.5614	Yes
42	ITPR3	ITPR3 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 3	2561	0.085	0.5662	Yes
43	GNB3	GNB3 Entrez, Source	guanine nucleotide binding protein (G protein), beta polypeptide 3	2846	0.076	0.5501	No
44	GNG3	GNG3 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 3	2978	0.072	0.5453	No
45	GNB4	GNB4 Entrez, Source	guanine nucleotide binding protein (G protein), beta polypeptide 4	3031	0.070	0.5463	No
46	PRKAR2A	PRKAR2A Entrez, Source	protein kinase, cAMP-dependent, regulatory, type II, alpha	3077	0.069	0.5478	No
47	ATP2B3	ATP2B3 Entrez, Source	ATPase, Ca++ transporting, plasma membrane 3	3129	0.068	0.5487	No
48	RGS6	RGS6 Entrez, Source	regulator of G-protein signalling 6	3368	0.061	0.5350	No
49	ATP1B2	ATP1B2 Entrez, Source	ATPase, Na+/K+ transporting, beta 2 polypeptide	3398	0.060	0.5371	No
50	SLC8A1	SLC8A1 Entrez, Source	solute carrier family 8 (sodium/calcium exchanger), member 1	3484	0.058	0.5347	No
51	PRKCZ	PRKCZ Entrez, Source	protein kinase C, zeta	3870	0.048	0.5090	No
52	CACNB3	CACNB3 Entrez, Source	calcium channel, voltage-dependent, beta 3 subunit	3904	0.047	0.5099	No
53	ARRB2	ARRB2 Entrez, Source	arrestin, beta 2	3976	0.045	0.5077	No
54	CHRM3	CHRM3 Entrez, Source	cholinergic receptor, muscarinic 3	4080	0.043	0.5029	No
55	CHRM2	CHRM2 Entrez, Source	cholinergic receptor, muscarinic 2	4127	0.042	0.5024	No
56	ADCY2	ADCY2 Entrez, Source	adenylate cyclase 2 (brain)	4158	0.041	0.5030	No
57	GNG7	GNG7 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 7	4166	0.041	0.5053	No
58	CAMK1	CAMK1 Entrez, Source	calcium/calmodulin-dependent protein kinase I	4262	0.038	0.5008	No
59	CAMK2A	CAMK2A Entrez, Source	calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha	4303	0.037	0.5005	No
60	KCNB1	KCNB1 Entrez, Source	potassium voltage-gated channel, Shab-related subfamily, member 1	4356	0.037	0.4991	No
61	CHRM4	CHRM4 Entrez, Source	cholinergic receptor, muscarinic 4	4648	0.031	0.4793	No
62	CAMK4	CAMK4 Entrez, Source	calcium/calmodulin-dependent protein kinase IV	4665	0.031	0.4803	No
63	RYR1	RYR1 Entrez, Source	ryanodine receptor 1 (skeletal)	4695	0.030	0.4802	No
64	ITPR2	ITPR2 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 2	4733	0.030	0.4795	No
65	CACNA1D	CACNA1D Entrez, Source	calcium channel, voltage-dependent, L type, alpha 1D subunit	4746	0.029	0.4806	No
66	PRKAR1A	PRKAR1A Entrez, Source	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	4750	0.029	0.4824	No
67	GJB6	GJB6 Entrez, Source	gap junction protein, beta 6 (connexin 30)	4849	0.027	0.4769	No
68	CHRM5	CHRM5 Entrez, Source	cholinergic receptor, muscarinic 5	4885	0.026	0.4762	No
69	RGS19	RGS19 Entrez, Source	regulator of G-protein signalling 19	5241	0.020	0.4507	No
70	CACNA1B	CACNA1B Entrez, Source	calcium channel, voltage-dependent, L type, alpha 1B subunit	5446	0.016	0.4364	No
71	GNAI3	GNAI3 Entrez, Source	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	5631	0.012	0.4233	No
72	PLCB3	PLCB3 Entrez, Source	phospholipase C, beta 3 (phosphatidylinositol-specific)	5675	0.011	0.4209	No
73	GJA4	GJA4 Entrez, Source	gap junction protein, alpha 4, 37kDa (connexin 37)	5689	0.011	0.4207	No
74	GNB2	GNB2 Entrez, Source	guanine nucleotide binding protein (G protein), beta polypeptide 2	5801	0.009	0.4130	No
75	RGS9	RGS9 Entrez, Source	regulator of G-protein signalling 9	5873	0.008	0.4081	No
76	CACNB1	CACNB1 Entrez, Source	calcium channel, voltage-dependent, beta 1 subunit	5959	0.006	0.4021	No
77	CAMK2D	CAMK2D Entrez, Source	calcium/calmodulin-dependent protein kinase (CaM kinase) II delta	5975	0.006	0.4014	No
78	GRK4	GRK4 Entrez, Source	G protein-coupled receptor kinase 4	5984	0.005	0.4012	No
79	GRK6	GRK6 Entrez, Source	G protein-coupled receptor kinase 6	6012	0.005	0.3995	No
80	PRKACA	PRKACA Entrez, Source	protein kinase, cAMP-dependent, catalytic, alpha	6017	0.005	0.3995	No
81	KCNJ3	KCNJ3 Entrez, Source	potassium inwardly-rectifying channel, subfamily J, member 3	6023	0.005	0.3995	No
82	YWHAB	YWHAB Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	6058	0.004	0.3972	No
83	KCNJ5	KCNJ5 Entrez, Source	potassium inwardly-rectifying channel, subfamily J, member 5	6397	-0.002	0.3717	No
84	GJB4	GJB4 Entrez, Source	gap junction protein, beta 4 (connexin 30.3)	6443	-0.002	0.3685	No
85	GNAO1	GNAO1 Entrez, Source	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	6475	-0.003	0.3664	No
86	CACNA1C	CACNA1C Entrez, Source	calcium channel, voltage-dependent, L type, alpha 1C subunit	6752	-0.008	0.3461	No
87	NME7	NME7 Entrez, Source	non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)	6771	-0.008	0.3453	No
88	ADRA1B	ADRA1B Entrez, Source	adrenergic, alpha-1B-, receptor	6830	-0.009	0.3416	No
89	CALM2	CALM2 Entrez, Source	calmodulin 2 (phosphorylase kinase, delta)	6851	-0.010	0.3407	No
90	GNAZ	GNAZ Entrez, Source	guanine nucleotide binding protein (G protein), alpha z polypeptide	7190	-0.016	0.3163	No
91	GNG5	GNG5 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 5	7340	-0.018	0.3063	No
92	YWHAH	YWHAH Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	7564	-0.023	0.2911	No
93	CAMK2G	CAMK2G Entrez, Source	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma	7620	-0.024	0.2886	No
94	GJA5	GJA5 Entrez, Source	gap junction protein, alpha 5, 40kDa (connexin 40)	7650	-0.025	0.2881	No
95	PRKCD	PRKCD Entrez, Source	protein kinase C, delta	7739	-0.026	0.2833	No
96	PRKCQ	PRKCQ Entrez, Source	protein kinase C, theta	7952	-0.030	0.2694	No
97	CACNA1A	CACNA1A Entrez, Source	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	8022	-0.032	0.2664	No
98	RGS14	RGS14 Entrez, Source	regulator of G-protein signalling 14	8231	-0.036	0.2533	No
99	RYR2	RYR2 Entrez, Source	ryanodine receptor 2 (cardiac)	8394	-0.039	0.2438	No
100	CAMK2B	CAMK2B Entrez, Source	calcium/calmodulin-dependent protein kinase (CaM kinase) II beta	8471	-0.041	0.2409	No
101	ADCY3	ADCY3 Entrez, Source	adenylate cyclase 3	8509	-0.042	0.2411	No
102	ATP2A2	ATP2A2 Entrez, Source	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	8616	-0.044	0.2361	No
103	CACNA1S	CACNA1S Entrez, Source	calcium channel, voltage-dependent, L type, alpha 1S subunit	8978	-0.051	0.2125	No
104	CHRM1	CHRM1 Entrez, Source	cholinergic receptor, muscarinic 1	9204	-0.056	0.1994	No
105	CASQ2	CASQ2 Entrez, Source	calsequestrin 2 (cardiac muscle)	9360	-0.060	0.1919	No
106	GNA11	GNA11 Entrez, Source	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	9547	-0.064	0.1823	No
107	GNG12	GNG12 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 12	9591	-0.065	0.1837	No
108	SLC8A3	SLC8A3 Entrez, Source	solute carrier family 8 (sodium-calcium exchanger), member 3	9596	-0.065	0.1880	No
109	ATP2B1	ATP2B1 Entrez, Source	ATPase, Ca++ transporting, plasma membrane 1	9817	-0.071	0.1764	No
110	ADCY8	ADCY8 Entrez, Source	adenylate cyclase 8 (brain)	9950	-0.075	0.1717	No
111	ATP2B2	ATP2B2 Entrez, Source	ATPase, Ca++ transporting, plasma membrane 2	9983	-0.076	0.1746	No
112	ADRA1A	ADRA1A Entrez, Source	adrenergic, alpha-1A-, receptor	10025	-0.077	0.1770	No
113	ADRB1	ADRB1 Entrez, Source	adrenergic, beta-1-, receptor	10250	-0.083	0.1659	No
114	PRKCE	PRKCE Entrez, Source	protein kinase C, epsilon	10468	-0.089	0.1558	No
115	ADCY4	ADCY4 Entrez, Source	adenylate cyclase 4	10641	-0.095	0.1495	No
116	CALM1	CALM1 Entrez, Source	calmodulin 1 (phosphorylase kinase, delta)	10674	-0.096	0.1539	No
117	PRKD1	PRKD1 Entrez, Source	protein kinase D1	11159	-0.115	0.1254	No
118	CALR	CALR Entrez, Source	calreticulin	11620	-0.135	0.1001	No
119	PRKCB1	PRKCB1 Entrez, Source	protein kinase C, beta 1	11650	-0.136	0.1075	No
120	ATP1B3	ATP1B3 Entrez, Source	ATPase, Na+/K+ transporting, beta 3 polypeptide	11707	-0.138	0.1130	No
121	GNB1	GNB1 Entrez, Source	guanine nucleotide binding protein (G protein), beta polypeptide 1	11879	-0.149	0.1106	No