Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CARBON_CARBON_LYASE_ACTIVITY |
| Enrichment Score (ES) | 0.70140946 |
| Normalized Enrichment Score (NES) | 1.7818385 |
| Nominal p-value | 0.0018416207 |
| FDR q-value | 0.031803943 |
| FWER p-Value | 0.974 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 127 | 0.610 | 0.1833 | Yes |
| 2 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 258 | 0.431 | 0.3100 | Yes |
| 3 | ACMSD | ACMSD Entrez, Source | aminocarboxymuconate semialdehyde decarboxylase | 328 | 0.374 | 0.4230 | Yes |
| 4 | HACL1 | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 490 | 0.289 | 0.5024 | Yes |
| 5 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 563 | 0.266 | 0.5811 | Yes |
| 6 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 817 | 0.210 | 0.6286 | Yes |
| 7 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 906 | 0.195 | 0.6837 | Yes |
| 8 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 1998 | 0.108 | 0.6359 | Yes |
| 9 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 2152 | 0.101 | 0.6565 | Yes |
| 10 | HDC | HDC Entrez, Source | histidine decarboxylase | 2155 | 0.101 | 0.6884 | Yes |
| 11 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 2507 | 0.088 | 0.6897 | Yes |
| 12 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 2692 | 0.081 | 0.7014 | Yes |
| 13 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 3477 | 0.058 | 0.6610 | No |
| 14 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 5039 | 0.023 | 0.5512 | No |
| 15 | UROD | UROD Entrez, Source | uroporphyrinogen decarboxylase | 6930 | -0.011 | 0.4128 | No |
| 16 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 9270 | -0.057 | 0.2555 | No |
| 17 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 9665 | -0.067 | 0.2471 | No |
| 18 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 10528 | -0.091 | 0.2112 | No |
