Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | CASPASEPATHWAY |
| Enrichment Score (ES) | -0.5130238 |
| Normalized Enrichment Score (NES) | -1.4197612 |
| Nominal p-value | 0.062370062 |
| FDR q-value | 0.27547362 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 1025 | 0.179 | 0.0109 | No |
| 2 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2541 | 0.086 | -0.0607 | No |
| 3 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 3164 | 0.067 | -0.0747 | No |
| 4 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3256 | 0.064 | -0.0502 | No |
| 5 | PRF1 | PRF1 Entrez, Source | perforin 1 (pore forming protein) | 3708 | 0.052 | -0.0586 | No |
| 6 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 4606 | 0.032 | -0.1103 | No |
| 7 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 4947 | 0.025 | -0.1236 | No |
| 8 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 5002 | 0.024 | -0.1158 | No |
| 9 | DFFA | DFFA Entrez, Source | DNA fragmentation factor, 45kDa, alpha polypeptide | 5035 | 0.023 | -0.1068 | No |
| 10 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 6929 | -0.011 | -0.2435 | No |
| 11 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 7532 | -0.022 | -0.2778 | No |
| 12 | BIRC2 | BIRC2 Entrez, Source | baculoviral IAP repeat-containing 2 | 7883 | -0.029 | -0.2899 | No |
| 13 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 8068 | -0.033 | -0.2877 | No |
| 14 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 9437 | -0.061 | -0.3603 | No |
| 15 | GZMB | GZMB Entrez, Source | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 9634 | -0.066 | -0.3426 | No |
| 16 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10524 | -0.091 | -0.3648 | No |
| 17 | LMNA | LMNA Entrez, Source | lamin A/C | 12500 | -0.199 | -0.4154 | Yes |
| 18 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 12574 | -0.208 | -0.3191 | Yes |
| 19 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13151 | -0.360 | -0.1858 | Yes |
| 20 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 13204 | -0.408 | 0.0104 | Yes |
