Details for gene set CELLULAR_LIPID_METABOLIC

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in class	double_gel_8d
GeneSet	CELLULAR_LIPID_METABOLIC_PROCESS
Enrichment Score (ES)	0.52621645
Normalized Enrichment Score (NES)	1.9791853
Nominal p-value	0.0
FDR q-value	0.0066572633
FWER p-Value	0.207

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HAO2	HAO2 Entrez, Source	hydroxyacid oxidase 2 (long chain)	18	1.071	0.0445	Yes
2	CPT1A	CPT1A Entrez, Source	carnitine palmitoyltransferase 1A (liver)	84	0.686	0.0689	Yes
3	ACOX2	ACOX2 Entrez, Source	acyl-Coenzyme A oxidase 2, branched chain	97	0.667	0.0965	Yes
4	SOAT1	SOAT1 Entrez, Source	sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1	100	0.661	0.1247	Yes
5	LPL	LPL Entrez, Source	lipoprotein lipase	107	0.646	0.1519	Yes
6	PEMT	PEMT Entrez, Source	phosphatidylethanolamine N-methyltransferase	142	0.579	0.1741	Yes
7	ST8SIA3	ST8SIA3 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	163	0.542	0.1957	Yes
8	ABCG1	ABCG1 Entrez, Source	ATP-binding cassette, sub-family G (WHITE), member 1	179	0.519	0.2168	Yes
9	SMPD3	SMPD3 Entrez, Source	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	248	0.442	0.2306	Yes
10	IHPK2	IHPK2 Entrez, Source	inositol hexaphosphate kinase 2	313	0.388	0.2423	Yes
11	B4GALNT1	B4GALNT1 Entrez, Source	beta-1,4-N-acetyl-galactosaminyl transferase 1	325	0.377	0.2576	Yes
12	FADS1	FADS1 Entrez, Source	fatty acid desaturase 1	330	0.373	0.2733	Yes
13	ECHS1	ECHS1 Entrez, Source	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	346	0.367	0.2879	Yes
14	ECH1	ECH1 Entrez, Source	enoyl Coenzyme A hydratase 1, peroxisomal	350	0.365	0.3033	Yes
15	GLYAT	GLYAT Entrez, Source	glycine-N-acyltransferase	379	0.348	0.3160	Yes
16	PLCE1	PLCE1 Entrez, Source	phospholipase C, epsilon 1	396	0.339	0.3293	Yes
17	SCARB1	SCARB1 Entrez, Source	scavenger receptor class B, member 1	431	0.321	0.3404	Yes
18	PLA1A	PLA1A Entrez, Source	phospholipase A1 member A	435	0.317	0.3538	Yes
19	HACL1	HACL1 Entrez, Source	2-hydroxyacyl-CoA lyase 1	490	0.289	0.3621	Yes
20	HSD3B1	HSD3B1 Entrez, Source	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	501	0.286	0.3735	Yes
21	RARRES2	RARRES2 Entrez, Source	retinoic acid receptor responder (tazarotene induced) 2	544	0.271	0.3819	Yes
22	DHCR24	DHCR24 Entrez, Source	24-dehydrocholesterol reductase	561	0.267	0.3921	Yes
23	ALDH5A1	ALDH5A1 Entrez, Source	aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)	595	0.258	0.4007	Yes
24	BAAT	BAAT Entrez, Source	bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)	602	0.257	0.4112	Yes
25	NR1I2	NR1I2 Entrez, Source	nuclear receptor subfamily 1, group I, member 2	609	0.256	0.4217	Yes
26	CHPT1	CHPT1 Entrez, Source	choline phosphotransferase 1	644	0.246	0.4297	Yes
27	APOA1	APOA1 Entrez, Source	apolipoprotein A-I	646	0.246	0.4401	Yes
28	APOM	APOM Entrez, Source	apolipoprotein M	687	0.238	0.4472	Yes
29	ASAH1	ASAH1 Entrez, Source	N-acylsphingosine amidohydrolase (acid ceramidase) 1	722	0.231	0.4545	Yes
30	MLYCD	MLYCD Entrez, Source	malonyl-CoA decarboxylase	817	0.210	0.4564	Yes
31	PECI	PECI Entrez, Source	peroxisomal D3,D2-enoyl-CoA isomerase	886	0.197	0.4597	Yes
32	SCP2	SCP2 Entrez, Source	sterol carrier protein 2	890	0.197	0.4679	Yes
33	FADS2	FADS2 Entrez, Source	fatty acid desaturase 2	934	0.190	0.4728	Yes
34	MVK	MVK Entrez, Source	mevalonate kinase (mevalonic aciduria)	998	0.183	0.4758	Yes
35	CLN8	CLN8 Entrez, Source	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	1037	0.178	0.4805	Yes
36	PPARGC1A	PPARGC1A Entrez, Source	peroxisome proliferative activated receptor, gamma, coactivator 1, alpha	1066	0.174	0.4859	Yes
37	DGAT1	DGAT1 Entrez, Source	diacylglycerol O-acyltransferase homolog 1 (mouse)	1067	0.174	0.4933	Yes
38	STS	STS Entrez, Source	steroid sulfatase (microsomal), arylsulfatase C, isozyme S	1105	0.170	0.4978	Yes
39	NSDHL	NSDHL Entrez, Source	NAD(P) dependent steroid dehydrogenase-like	1169	0.164	0.5000	Yes
40	RETSAT	RETSAT Entrez, Source	retinol saturase (all-trans-retinol 13,14-reductase)	1210	0.160	0.5038	Yes
41	FDPS	FDPS Entrez, Source	farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)	1211	0.160	0.5107	Yes
42	TSPO	TSPO Entrez, Source	translocator protein (18kDa)	1265	0.154	0.5133	Yes
43	PLA2G5	PLA2G5 Entrez, Source	phospholipase A2, group V	1299	0.151	0.5172	Yes
44	APOA5	APOA5 Entrez, Source	apolipoprotein A-V	1486	0.136	0.5089	Yes
45	ACADS	ACADS Entrez, Source	acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain	1544	0.132	0.5103	Yes
46	SMPD2	SMPD2 Entrez, Source	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)	1566	0.130	0.5142	Yes
47	HPGD	HPGD Entrez, Source	hydroxyprostaglandin dehydrogenase 15-(NAD)	1689	0.123	0.5103	Yes
48	PEX7	PEX7 Entrez, Source	peroxisomal biogenesis factor 7	1696	0.123	0.5151	Yes
49	ACADSB	ACADSB Entrez, Source	acyl-Coenzyme A dehydrogenase, short/branched chain	1715	0.122	0.5189	Yes
50	DHRS9	DHRS9 Entrez, Source	dehydrogenase/reductase (SDR family) member 9	1778	0.118	0.5193	Yes
51	IDI1	IDI1 Entrez, Source	isopentenyl-diphosphate delta isomerase 1	1830	0.115	0.5203	Yes
52	PLCD1	PLCD1 Entrez, Source	phospholipase C, delta 1	1867	0.113	0.5225	Yes
53	APOC3	APOC3 Entrez, Source	apolipoprotein C-III	1882	0.113	0.5262	Yes
54	ST6GALNAC6	ST6GALNAC6 Entrez, Source	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	2068	0.105	0.5167	No
55	AKR1D1	AKR1D1 Entrez, Source	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	2111	0.103	0.5179	No
56	DGAT2	DGAT2 Entrez, Source	diacylglycerol O-acyltransferase homolog 2 (mouse)	2209	0.099	0.5148	No
57	PSAP	PSAP Entrez, Source	prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)	2220	0.099	0.5182	No
58	PPAP2A	PPAP2A Entrez, Source	phosphatidic acid phosphatase type 2A	2313	0.095	0.5153	No
59	NR0B2	NR0B2 Entrez, Source	nuclear receptor subfamily 0, group B, member 2	2330	0.094	0.5181	No
60	PPT1	PPT1 Entrez, Source	palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)	2353	0.093	0.5205	No
61	LYPLA3	LYPLA3 Entrez, Source	lysophospholipase 3 (lysosomal phospholipase A2)	2431	0.090	0.5185	No
62	ACOT12	ACOT12 Entrez, Source	acyl-CoA thioesterase 12	2485	0.088	0.5183	No
63	AGPAT1	AGPAT1 Entrez, Source	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	2510	0.088	0.5202	No
64	CYP19A1	CYP19A1 Entrez, Source	cytochrome P450, family 19, subfamily A, polypeptide 1	2640	0.082	0.5139	No
65	DPM2	DPM2 Entrez, Source	dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit	2678	0.081	0.5146	No
66	GPX4	GPX4 Entrez, Source	glutathione peroxidase 4 (phospholipid hydroperoxidase)	2713	0.080	0.5154	No
67	LCAT	LCAT Entrez, Source	lecithin-cholesterol acyltransferase	2888	0.075	0.5054	No
68	PIGS	PIGS Entrez, Source	phosphatidylinositol glycan anchor biosynthesis, class S	2958	0.072	0.5033	No
69	ACADVL	ACADVL Entrez, Source	acyl-Coenzyme A dehydrogenase, very long chain	3002	0.071	0.5030	No
70	PIGK	PIGK Entrez, Source	phosphatidylinositol glycan anchor biosynthesis, class K	3013	0.071	0.5053	No
71	FAAH	FAAH Entrez, Source	fatty acid amide hydrolase	3091	0.069	0.5024	No
72	BMP6	BMP6 Entrez, Source	bone morphogenetic protein 6	3348	0.061	0.4856	No
73	ADIPOR1	ADIPOR1 Entrez, Source	adiponectin receptor 1	3394	0.060	0.4848	No
74	PCYT2	PCYT2 Entrez, Source	phosphate cytidylyltransferase 2, ethanolamine	3493	0.058	0.4798	No
75	LTA4H	LTA4H Entrez, Source	leukotriene A4 hydrolase	3505	0.057	0.4815	No
76	ST8SIA1	ST8SIA1 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	3554	0.056	0.4802	No
77	DEGS1	DEGS1 Entrez, Source	degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)	3581	0.055	0.4806	No
78	ACADM	ACADM Entrez, Source	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	3794	0.050	0.4667	No
79	IMPA1	IMPA1 Entrez, Source	inositol(myo)-1(or 4)-monophosphatase 1	3908	0.047	0.4601	No
80	HSD11B2	HSD11B2 Entrez, Source	hydroxysteroid (11-beta) dehydrogenase 2	4357	0.037	0.4277	No
81	GBA2	GBA2 Entrez, Source	glucosidase, beta (bile acid) 2	4489	0.034	0.4193	No
82	MBTPS2	MBTPS2 Entrez, Source	membrane-bound transcription factor peptidase, site 2	4585	0.032	0.4134	No
83	CYP11A1	CYP11A1 Entrez, Source	cytochrome P450, family 11, subfamily A, polypeptide 1	4649	0.031	0.4100	No
84	PLCB2	PLCB2 Entrez, Source	phospholipase C, beta 2	4867	0.027	0.3947	No
85	PRDX6	PRDX6 Entrez, Source	peroxiredoxin 6	4883	0.026	0.3947	No
86	NEU3	NEU3 Entrez, Source	sialidase 3 (membrane sialidase)	4899	0.026	0.3946	No
87	CEL	CEL Entrez, Source	carboxyl ester lipase (bile salt-stimulated lipase)	5047	0.023	0.3845	No
88	ACOT2	ACOT2 Entrez, Source	acyl-CoA thioesterase 2	5165	0.021	0.3765	No
89	SULT2A1	SULT2A1 Entrez, Source	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	5184	0.021	0.3760	No
90	ABCD2	ABCD2 Entrez, Source	ATP-binding cassette, sub-family D (ALD), member 2	5216	0.020	0.3745	No
91	ST8SIA5	ST8SIA5 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	5258	0.020	0.3723	No
92	CPT1B	CPT1B Entrez, Source	carnitine palmitoyltransferase 1B (muscle)	5265	0.019	0.3726	No
93	B4GALT4	B4GALT4 Entrez, Source	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	5335	0.018	0.3682	No
94	SERINC2	SERINC2 Entrez, Source	serine incorporator 2	5340	0.018	0.3686	No
95	UGCG	UGCG Entrez, Source	UDP-glucose ceramide glucosyltransferase	5384	0.017	0.3661	No
96	ADIPOR2	ADIPOR2 Entrez, Source	adiponectin receptor 2	5506	0.014	0.3576	No
97	PPARD	PPARD Entrez, Source	peroxisome proliferative activated receptor, delta	5532	0.014	0.3563	No
98	PTGS1	PTGS1 Entrez, Source	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	5556	0.014	0.3551	No
99	DHCR7	DHCR7 Entrez, Source	7-dehydrocholesterol reductase	5728	0.010	0.3426	No
100	SC4MOL	SC4MOL Entrez, Source	sterol-C4-methyl oxidase-like	5880	0.008	0.3315	No
101	PTGDS	PTGDS Entrez, Source	prostaglandin D2 synthase 21kDa (brain)	5900	0.007	0.3303	No
102	ASAH2	ASAH2 Entrez, Source	N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2	6047	0.004	0.3194	No
103	PCYT1B	PCYT1B Entrez, Source	phosphate cytidylyltransferase 1, choline, beta	6229	0.001	0.3057	No
104	PTGES	PTGES Entrez, Source	prostaglandin E synthase	6415	-0.002	0.2918	No
105	IHPK1	IHPK1 Entrez, Source	inositol hexaphosphate kinase 1	6458	-0.003	0.2887	No
106	PI4K2A			6643	-0.006	0.2750	No
107	CYP7B1	CYP7B1 Entrez, Source	cytochrome P450, family 7, subfamily B, polypeptide 1	7069	-0.014	0.2434	No
108	SPHK1	SPHK1 Entrez, Source	sphingosine kinase 1	7090	-0.014	0.2425	No
109	SOD1	SOD1 Entrez, Source	superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))	7093	-0.014	0.2429	No
110	FDXR	FDXR Entrez, Source	ferredoxin reductase	7183	-0.015	0.2368	No
111	STUB1	STUB1 Entrez, Source	STIP1 homology and U-box containing protein 1	7226	-0.016	0.2344	No
112	NPC2	NPC2 Entrez, Source	Niemann-Pick disease, type C2	7253	-0.017	0.2331	No
113	NR0B1	NR0B1 Entrez, Source	nuclear receptor subfamily 0, group B, member 1	7399	-0.020	0.2230	No
114	RDH11	RDH11 Entrez, Source	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	7495	-0.022	0.2167	No
115	YWHAH	YWHAH Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	7564	-0.023	0.2125	No
116	HADHB	HADHB Entrez, Source	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	7978	-0.031	0.1825	No
117	SERINC1	SERINC1 Entrez, Source	serine incorporator 1	8027	-0.032	0.1802	No
118	CD81	CD81 Entrez, Source	CD81 molecule	8032	-0.032	0.1813	No
119	SHH	SHH Entrez, Source	sonic hedgehog homolog (Drosophila)	8114	-0.034	0.1766	No
120	CYP4F2	CYP4F2 Entrez, Source	cytochrome P450, family 4, subfamily F, polypeptide 2	8129	-0.034	0.1770	No
121	TNFRSF1A	TNFRSF1A Entrez, Source	tumor necrosis factor receptor superfamily, member 1A	8306	-0.037	0.1652	No
122	HSD3B7	HSD3B7 Entrez, Source	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	8340	-0.038	0.1644	No
123	AKR1B10	AKR1B10 Entrez, Source	aldo-keto reductase family 1, member B10 (aldose reductase)	8361	-0.039	0.1645	No
124	SPTLC1	SPTLC1 Entrez, Source	serine palmitoyltransferase, long chain base subunit 1	8481	-0.041	0.1572	No
125	ST3GAL6	ST3GAL6 Entrez, Source	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	8557	-0.043	0.1534	No
126	PNLIPRP2	PNLIPRP2 Entrez, Source	pancreatic lipase-related protein 2	8921	-0.050	0.1280	No
127	HDLBP	HDLBP Entrez, Source	high density lipoprotein binding protein (vigilin)	9423	-0.061	0.0926	No
128	PLA2G6	PLA2G6 Entrez, Source	phospholipase A2, group VI (cytosolic, calcium-independent)	9476	-0.062	0.0914	No
129	PIP5K1A	PIP5K1A Entrez, Source	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	9484	-0.063	0.0935	No
130	AGPAT6	AGPAT6 Entrez, Source	1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)	9694	-0.068	0.0805	No
131	PLA2G2D	PLA2G2D Entrez, Source	phospholipase A2, group IID	9730	-0.069	0.0808	No
132	NR1H4	NR1H4 Entrez, Source	nuclear receptor subfamily 1, group H, member 4	9939	-0.075	0.0683	No
133	PIGC	PIGC Entrez, Source	phosphatidylinositol glycan anchor biosynthesis, class C	10365	-0.086	0.0397	No
134	SERINC5	SERINC5 Entrez, Source	serine incorporator 5	10779	-0.100	0.0127	No
135	ACOX3	ACOX3 Entrez, Source	acyl-Coenzyme A oxidase 3, pristanoyl	10884	-0.104	0.0093	No
136	ADM	ADM Entrez, Source	adrenomedullin	11063	-0.110	0.0005	No
137	BRCA1	BRCA1 Entrez, Source	breast cancer 1, early onset	11096	-0.112	0.0029	No
138	PIK3R1	PIK3R1 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)	11304	-0.121	-0.0077	No
139	CNBP	CNBP Entrez, Source	CCHC-type zinc finger, nucleic acid binding protein	11520	-0.130	-0.0184	No
140	GNPAT	GNPAT Entrez, Source	glyceronephosphate O-acyltransferase	11617	-0.134	-0.0199	No
141	IL4	IL4 Entrez, Source	interleukin 4	11640	-0.135	-0.0158	No
142	PLAA	PLAA Entrez, Source	phospholipase A2-activating protein	11873	-0.149	-0.0270	No
143	CLN3	CLN3 Entrez, Source	ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)	11907	-0.150	-0.0231	No
144	PTEN	PTEN Entrez, Source	phosphatase and tensin homolog (mutated in multiple advanced cancers 1)	11925	-0.152	-0.0179	No
145	CROT	CROT Entrez, Source	carnitine O-octanoyltransferase	11938	-0.152	-0.0123	No
146	ST6GALNAC4	ST6GALNAC4 Entrez, Source	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	11980	-0.156	-0.0087	No
147	MIF	MIF Entrez, Source	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	12291	-0.179	-0.0246	No
148	PPARA	PPARA Entrez, Source	peroxisome proliferative activated receptor, alpha	12405	-0.189	-0.0251	No
149	DHRS3	DHRS3 Entrez, Source	dehydrogenase/reductase (SDR family) member 3	12528	-0.202	-0.0257	No
150	PIGV	PIGV Entrez, Source	phosphatidylinositol glycan anchor biosynthesis, class V	12538	-0.203	-0.0177	No
151	AGPS	AGPS Entrez, Source	alkylglycerone phosphate synthase	13056	-0.309	-0.0437	No
152	SGPL1	SGPL1 Entrez, Source	sphingosine-1-phosphate lyase 1	13181	-0.384	-0.0366	No
153	SLC27A5	SLC27A5 Entrez, Source	solute carrier family 27 (fatty acid transporter), member 5	13261	-0.509	-0.0208	No
154	CD74	CD74 Entrez, Source	CD74 molecule, major histocompatibility complex, class II invariant chain	13307	-0.629	0.0027	No