Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | CELL_CYCLE_CHECKPOINT |
| Enrichment Score (ES) | -0.5893479 |
| Normalized Enrichment Score (NES) | -1.4963692 |
| Nominal p-value | 0.057086613 |
| FDR q-value | 0.22835484 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 1377 | 0.144 | -0.0444 | No |
| 2 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 1445 | 0.139 | 0.0073 | No |
| 3 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 2183 | 0.100 | -0.0072 | No |
| 4 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 6622 | -0.006 | -0.3377 | No |
| 5 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 6873 | -0.010 | -0.3524 | No |
| 6 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 8016 | -0.032 | -0.4252 | No |
| 7 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 10205 | -0.082 | -0.5560 | Yes |
| 8 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 10530 | -0.091 | -0.5432 | Yes |
| 9 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 11096 | -0.112 | -0.5399 | Yes |
| 10 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11266 | -0.119 | -0.5040 | Yes |
| 11 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12006 | -0.158 | -0.4950 | Yes |
| 12 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 12556 | -0.205 | -0.4524 | Yes |
| 13 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.3595 | Yes |
| 14 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13163 | -0.372 | -0.2125 | Yes |
| 15 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | 0.0041 | Yes |
